半月板囊肿的关节镜下手术治疗临床分析

目的探讨关节镜下半月板囊肿手术治疗的方法及其疗效。方法对21例半月板囊肿患者采取关节镜下囊肿切除,同时根据半月板损伤情况行半月板缝合或部分切除,并采用Lysholm评分在术前、术后对膝关节肿痛及活动受限等症状进行分析比较。结果全部患者均获随访,随访时间6~36个月,未见囊肿复发及明显术后并发症。Lysholm评分术前平均(71.3±5.6)分,术后显著增高到(94.8±3.2)分,术后膝关节评分较术前有明显增幅(P0.05)。结论通过关节镜下手术治疗膝关节半月板囊肿,不仅对膝关节肿痛及活动受限等症状有明显的改善,并且保留了创伤小、恢复快的微创手术优势。     

关节镜下关节内减压术治疗半月板周围型囊肿

目的：探讨关节镜下联合囊肿关节内减压术及半月板部分切除或缝合治疗半月板周围型囊肿（parameniscal cysts,PC）的疗效。方法：2009年1月至2011年12月,对22例PC患者采用关节镜下联合囊肿关节内减压术及半月板部分切除或缝合治疗。男性14例,女性8例;年龄22～51岁,平均32.7岁;左膝12例,右膝10例。18例有明确外伤史,其余患者均无明显诱因。病程3～12个月,平均5.2个月。术前Lysholm评分为（60.03±4.89）分,国际膝关节文献委员会（International Knee Documentation Committee,ＩＫＤＣ）分为（64.25±4.22）分。关节镜下见其中外侧半月板18例,内侧半月板4例,按具体部位分前角7例,体部14例,后角1例;所有囊肿均为单发,其中5例为多房。结果：术后切口均Ⅰ期愈合,无伤口感染、神经、血管损伤等早期并发症发生。术后22例均获随访,随访时间12～24个月,平均 14.5个月。患者术前症状消失或明显减轻,关节活动度恢复正常。术后12个月Lysholm评分为（87.20±4.65）分,IKDC评分为（90.86±3.58）分,与术前比较差异均有统计学意义（P<0.05）。采用Glasgow评定标准进行疗效评定,获优16例,良5例,中1例,优良率达95.45%。随访期间囊肿均无复发。结论：膝关节镜下联合囊肿关节内减压术及半月板部分切除或缝合治疗PC创伤小、康复快,可获得确切的临床疗效。     

Fast-Fix半月板缝合器治疗半月板损伤61例临床分析

目的 探讨关节镜下使用Fast-Fix半月板缝合器治疗半月板损伤的疗效.方法 回顾分析2008年9月～2010年9月采用关节镜下Fast-Fix半月板缝合器治疗半月板损伤共61例.采用Lysholm评分系统比较术前及术后膝关节功能.结果 术后随访时间8～30个月,平均18个月,术后无血管、神经损伤及切口感染等并发症.Lysholm评分:术前(47.7±15.9)分,术后(83.7±12.4)分(P＜0.001),优良率90.2％.结论 关节镜下使用Fast-Fix半月板缝合器治疗半月板损伤创伤小、恢复快,是一种操作简便、安全有效的治疗方式.     

关节镜下治疗半月板囊肿

目的：探讨关节镜下半月板囊肿手术治疗的疗效及临床应用价值。方法：应用关节镜技术对患者开展半月板囊肿手术治疗,并将手术前和手术后患者的状况进行比较。结果：手术前患者的膝关节功能（Lysholm）评分为（39．24±8．35）分,手术后提高至（89．26±8．96）分。结论：关节镜下半月板囊肿的手术治疗能够保留半月板的组织功能、减少膝关节骨性关节炎的发生概率,是治疗半月板囊肿的有效方法。     

关节镜下手术治疗膝关节半月板损伤39例临床观察

目的观察关节镜下手术治疗膝关节半月板损伤的临床治疗效果。方法对39例膝关节半月板损伤患者(观察组)应用关节镜下手术治疗,根据半月板损伤的类型分别进行处理,术后随访观察;并与40例半月板全切除术患者(对照组)进行比较,采用Lysholm膝关节功能评分评价手术治疗效果。结果所有患者均获得随访,平均随访时间(13.5±3.6)个月(2～32个月);观察组Lysholm-Ⅱ评分术前平均(45.1±2.1)分,术后平均(90.7±12.5)分,对照组术前评分平均(45.0±2.3)分,术后平均(75.3±11.8)分,两组治疗效果具有统计学意义(P0.01)。结论关节镜下手术治疗膝关节半月板损伤能最大限度地保留半月板,创伤小,恢复快,疗效佳,有利于早期功能锻炼。     

关节镜手术在陈旧性半月板损伤治疗中的应用

目的探讨关节镜手术治疗陈旧性半月板损伤的临床疗效。方法选择我院2010年3月-2011年1月间收治的40例陈旧性半月板损伤患者,术前患者膝关节Lysholm评分为（48.51±2.71）分,均在连续硬膜外麻醉下行关节镜手术,比较患者治疗前后膝关节Lysholm评分。结果术后所有患者均获得随访,术后患者膝关节Lysholm评分为（71.25±2.81）分,较治疗前明显提高,比较具有统计学差异,（P〈0.01）。结论在陈旧性半月板损伤中应用关节镜手术,具有损伤小、确诊率高等优点,术后患者膝关节明显缓解,病变关节功能得到有效缓解,值得临床推广。     

关节镜治疗色素沉着绒毛结节性滑膜炎的临床疗效分析

目的探讨关节镜治疗色素沉着绒毛结节性滑膜炎(PVS)的临床疗效.方法选取我院于2009年1月-2010年12月关节镜下行滑膜全切术的PVS患者19例,术前均行X线及MRI检查.结果术后随访1年,无手术并发症发生.术后IKDC膝关节功能主观评分为(83.58±3.53)分,Lysholm膝关节评分(82.75±2.74)分.而术前IKDC膝关节功能主观评分为(52.86±3.02)分,Lysholm膝关节评分(51.20±2.89)分,二者相比差异均具有统计学意义(均<0.05).结论 PVS患者于关节镜下行滑膜全切术疗效确切,创伤较小,术后膝关节功能恢复良好.     

关节镜下外内缝合法和全内缝合法治疗膝关节外侧盘状半月板损伤对术后疼痛及关节功能的影响

目的探讨关节镜下外内缝合法和全内缝合法治疗膝关节外侧盘状半月板损伤对术后疼痛和关节功能的影响。方法随机抽选2019年1月至2020年12月郑州市骨科医院接收的80例膝关节外侧盘状半月板损伤患者,按照随机数字表法分为对照组与观察组各40例,分别实施关节镜下外内缝合法与关节镜下全内缝合法,对两组膝关节功能、手术相关指标、视觉模拟评分法(VAS)评分和Lysholm评分进行对比分析。结果对照组膝关节功能治疗优良率为90.00%,观察组为95.00%,两组比较差异无统计学意义(P0.05);对照组手术时间为(45.78±9.25) min,观察组为(36.32±8.47) min,观察组短于对照组(P0.05);两组术中出血量差异无统计学意义(P0.05);两组术前VAS评分和Lysholm评分差异无统计学意义(P0.05);术后,对照组分别为(3.15±0.79)分和(72.56±2.31)分,观察组分别为(2.32±0.47)分和(76.05±1.74)分,观察组均优于对照组(P0.05)。结论膝关节外侧盘状半月板损伤治疗过程中,关节镜下外内缝合法与关节镜下全内缝合法均具有显著效果,但是全内缝合法操作更加简单,其可以减少手术时间,减轻治疗疼痛程度,及早恢复膝关节功能,值得临床进一步采纳与推广。     

膝关节盘状半月板损伤关节镜下手术治疗的临床分析

目的：评价膝关节盘状半月板损伤关节镜下手术治疗的临床疗效。方法：采用关节镜微创手术对96例膝关节盘状半月板损伤的患者进行治疗,应用Lysholm膝关节功能评分系统对手术效果及术后关节功能恢复情况进行评定及结果讨论。结果：术前关节功能平均96分（39-72分）,随访时关节功能平均91.6分（77-100分）。结论：膝关节盘状半月板损伤关节镜下手术治疗安全有效。     

微创关节镜手术治疗膝关节半月板损伤的疗效分析

目的 探讨微创关节镜手术治疗膝关节半月板损伤的疗效.方法 整群选择2014年5月—2016年5月期间该院收治的膝关节半月板损伤患者116例,以随机数字表法将其均分为两组,即研究组与对照组各58例.对照组采取开放性半月板切除手术,研究组采取微创关节镜手术.采用Lysholm膝关节评分标准对比两组患者术前与术后6个月时膝关节功能的变化,并观察两组术后并发症情况.结果 研究组术前Lysholm膝关节评分为(44.5±1.5)分、术后为(91.5±10.5)分,对照组术前Lysholm膝关节评分为(44.8±1.3)分、术后为(74.5±10.3)分.两组术后Lysholm膝关节评分均高于术前(P<0.05),且术后研究组Lysholm膝关节评分高于对照组,差异有统计学意义(P<0.05).研究组术后并发症发生率1.72%高于对照组13.79%,差异有统计学意义(P<0.05).结论 微创关节镜手术治疗膝关节半月板损伤具有显著的临床疗效,可以有效改善患者的膝关节功能,安全可靠,适于临床推广.     

Value of D-Dimers in patients with acute aortic dissection

Objective: To evaluatel the value of D-dimers in patients with acute aortic dissection (AAD). Methods: This study consisted of 16 patients with AAD and 27 non-AAD patients. Serum D-dimets were measured by Sta-Liatest D-DI immunoturbidimetric assay. Results: D-dimer level was higher (P ＜ 0.001) in patients with AAD(7.91 ± 5.52 μg/ml) than that in non- AAD group(1.57±1.24 μg/ml). D-dimer was positive (＞0.4 μg/ml) in all patients with AAD and in 10 control group patients (37%). Among patients with acute AAD, D-dimers tended to be higher in Stanford A than in Stanford B (8.67 ± 4.31 μg/ml vs. 3.24±1.27 μg/ml, P ＜0.01). D-dimer values tended to be higher in more extended disease(3.84 ± 1.65 μg/ml, 8.57 ± 3.58 μg/ml and 11.87 ± 5.69 μg/ml in thoracic aorta, thoracic and abdominal aorta, thoracic and abdominal aorta and iliacal arteries, respectively, P ＜ 0.05 for both 8.57 ± 3.58 and 11.87 ± 5.69 vs. 3.84 ± 1.65 ). Including the control group into the analysis, we found a sensitivity of 100%, a negative predictive value of 100%, and a specificity of 66% and a positive predictive value of 64% for D-dimer in diagnosis of AAD in our patients with suspected AAD. Conclusion: D-dimer was elevated in patients with AAD. A negative D-dimer test result could be useful in excluding AAD.     

Research of combined liver-kidney transplantation model in rats

Objective： To set up a simple and reliable rat model of combined liver-kidney transplantation. Methods： SD rats served as both donors and recipients. 4℃ sodium lactate Ringer＇s was infused from portal veins to donated livers,and from abdominal aorta to donated kidneys, respectively. Anastomosis of the portal vein and the inferior vena cava （IVC） inferior to the right kidney between the graft and the recipient was performed by a double cuff method, then the superior hepatic vena cava with suture. A patch of donated renal artery was anastomosed to the recipient abdominal aorta. The urethra and bile duct were reconstructed with a simple inside bracket. Results： Among 65 cases of combined liver-kidney transplantation, the success rate in the late 40 cases was 77.5%. The function of the grafted liver and kidney remained normal. Conclusion： This rat model of combined liver-kidney transplantation can be established in common laboratory conditions with high success rate and meet the needs of renal transplantation experiment.     

APPLICATION OF LORNOXICAM TO PATIENT-CONTROLLED ANALGESIA IN PATIENTS UNDERGOING ABDOMINAL SURGERIES

FOR anesthesiologis s ,treatingpostoperativepainhas alwaysbeen a problem.Althoughopioidshave been provedtobe effective,theirsideeffectscouldnotbeignored.With thedevelopmentofscienceand pharmacology,many drugs with aspectsof satisfactoryanalgesicefficacyand couldbe welltoleratedby patientshave been developed.And lornoxicamisone of them, which isa non-steroidalanti-inflammatorydrug (NSAID ), with analgesic, anti-infl-ammatory,andantipyreticproperties.Itseliminationhalf-time(3 to 5 hours) isle…     

BLOOD PRESSURE CHANGE WITH AGE IN SALT-SENSITIVE TEENAGERS

Objective To observe blood pressure change with age in salt-sensitive teenagers whose salt sensitivity were determined by repeated testing.Methods Salt sensitivity was determined through intravenous infusion of normal saline combined with volume-depletion by oral diuretic furosemide in 55 teenagers. After five years, salt sensitivity was re-examined and subject blood pressure was followed up. Blood pressure changes in salt-sensitive teenagers were compared to that of non-salt sensitive teenagers over five years.Results After 5 years, the repetition rate of salt sensitivity determined by intravenous saline loading is 92.7%. In teenagers with salt sensitivity on the baseline, both the systolic blood pressure increments and increment rates were much higher than non-salt sensitive teenagers (12.7±12.1 mmHg vs. 2.8±5.2 mmHg, P＜ 0.01; 12.2%± 12.0% vs. 2.5% ±4.4%, P＜ 0.001,respectively). There was a similar trend for diastolic blood pressure (8.4 ± 6.4 mmHg vs. 3.7 ± 6.4 mmHg, P = 0.052; 13.2% ±10.6 % vs. 6.8%± 10.1%, P = 0.053, respectively).Conclusions Salt sensitivity determined by intravenous saline loading showed good reproducibility. Blood pressure increments with age were much higher in salt-sensitive teenagers than non-salt sensitive teenagers, especially in terms of systolic blood pressure.     

Acupuncture Combined with Spinal Tui Na for Treatment of Primary Dysmenorrhea in 30 Cases

Objective: To observe the therapeutic effects in acupunture treatment of primary dysmenorrhea combined with spinal Tui Na, and study its mechanism. Methods: Thirty cases of the treatment group were treated by acupuncture combined with spinal Tui Na, and thirty cases in the control group were treated by routine acupuncture. Results: The total effective rate was 93.3% in the treatment group, and 73.3% in the control group, with a significant difference between the two groups (P<0.05). Conclusions: Acupuncture combined with spinal Tui Na has good prospects for treatment of primary dysmenorrhea.     

Luo Lingjie's Experience in Treating Chronic Nephropathy

In treating chronic nephropathy,Luo Lingjie,a chief physician,pays attention to regulating the balance between yin and yang,treating infection if present,and removing pathogenic factors.He prescribes gentle drugs and uses carefully strongly warming-tonifying ones,emphasizes the importance of persuading the patient to persist in treatment with medication and nurse one's health for recuperation,and is good at combined use of TCM and western medicine therapy and brings the merits of various therapies into full play,with obvious theraoeutic effects.     

Dr.Zhang Ren's Experience in the Acupuncture Treatment of Different Diseases with the Same Therapeutic Principle

Dr.Zhang Ren,the chief physician,is the chairman of Shanghai Acupuncture and Moxibustion Association.Having been engaged in medicine for about 40 years,he is experienced in treating various intractable diseases.In his long years of clinical practice,he advocates taking the TCM differentiation as the basis to seek for the acupuncture method for treatment of modern intractable diseases.The author of this essay had the fortune to follow Dr.Zhang in study.The following is a summary of Dr.Zhang's experience in the acupuncture treatment for different intractable diseases with the same therapeutic principle.     

安心颗粒对急诊经皮冠状动脉介入术后生活质量影响的研究

目的：评价使用安心颗粒对急诊经皮冠状动脉介入术（PPCI）术后生活质量的影响.方法：将160例接受PPCI的急性ST段抬高型心肌梗死患者随机分为安心颗粒组（术前顿服安心颗粒8.8g,术后安心颗粒4.4 g/次,每日2次）和对照组（仅接受基础药物治疗）.所有患者均服用阿司匹林、氯吡格雷和阿托伐他汀.分别在入院时、出院前1d、出院后180 d时,应用心肌梗死多维度量表（MIDAS）、中文版SF-36评价量表对患者生活质量评分.并观察术后30 d以内的出血并发症、血小板减少症发生情况.结果：入院时和出院前1d,两组患者的心肌梗死MIDAS、SF-36量表评分比较无差异（P＞0.05）;出院后180 d时,与对照组比较,安心颗粒组MIDAS、SF-36评分明显减低（P＜0.05）;组内与入院时比较,两组出院前1d、出院后180 d时,MIDAS、SF-36评分均降低（P＜0.05）.两组患者在随访期间均无大量出血、少量出血、重度和极重度血小板减少症发生,安心颗粒组有4例、对照组有7例发生不明显出血（P＞0.05）.两组发生轻度血小板减少症的患者数比较无差异（P＞0.05）.结论：PPCI使用安心颗粒,能改善急性ST段抬高型心肌梗死患者的生活质量,且不增加出血风险.     

The comparative studies of the influences of Urapidil and Nicardipine on sino-atrial node function, atrio-ventricular node function and hemodynamics

Objective:To investigate the influences of urapidil and nicardipine on rabbit sinus function,atrio-ventricular node function and hemodynamics.Methods:Thirty-two Angora's rabbits were selected and randomly divided into four groups.U1 group:urapidil 0.25 mg/kg;U2 group:urapidil 0.5 mg/kg;N1 group:nicardipine 10 μg/kg;N2 group:nicardipine 20 μg/kg.All these medicine were administrated within 30 seconds.Measurements were taken before and after the administration of urapidil or nicardipine for the following data:mean blood pressure(MAP),heart rate(HR),sino-atrial conduction time(SACT),maximal sinoatrial recovery time(SNRTmax)corrected sinus node recovery time(CSNRT),index of sinus node recovery time(SNRTI),Wenckebach A-V conduction frequency (WB),and P-R interval.Results:Significant MAP and HR changes were identified in all of the four groups before and after administration of both urapidil and nicardipine.No significant changes could be found in the rest of the parameters.Intergroup analysis showed that SACT and CSNRT of N1 and N2 groups were shorter than those of the U2 group(P＜0.01);the MAP decreased(P＜0.01)and the HR increased drastically(P＜0.01).Conclusions:Neither urapidil(0.25 mg/kg,0.5 mg/kg)nor nicardipine(10μg/kg,20μg/kg)has any significant influence on rabbit sinus function or rabbit atrio-ventricular node function.Nicardipine could be a better choice than urapidil for parafunctional sinus node patients.