F30066对家兔肝肾功能的影响

F 30066,化学名称β-(5-硝基-2-呋喃)丙烯酰异丙胺,是治疗日本血吸虫病的新药.由于多数药物由肝脏解毒,肾脏排出,用F30066治疗动物血吸虫病的过程中也发现药物对小白鼠、家兔及犬的肝、肾组织产生不同程度的病变;因此进一步观察了F30066对家兔肝、肾功能的影响,以供临床参考.同时也观察了正常家兔的几项常用肝、肾功能指标正常值的分布情况.     

胰腺假性囊肿经皮肤引流

本文报告在超声控制下经皮肤通过腹膜针刺吸引治疗9例10处胰腺假性囊肿。材料与方法:共7例男性及2例女性患者,平均年龄47岁(24～70岁),病程24小时～3个月。胰腺假性囊肿系以超声检查诊断。局麻下用22号Chiba穿刺针垂直向下刺至超声确定的深度和部位,尽量将囊肿抽空。偶因囊内液体粘稠而须用18号穿刺针。结果:共作34次抽吸,无并发症。患者疼痛均感缓解。4例假性囊肿经一次抽引治疗,3例痊愈。     

F30066对家兔肝肾功能的影响

F30066, N-(isopropyl)-β-(5-nitro-2-furyl)-acrylamide, is a new oral drug for Schis- tosomiasis japonica. The present work studied the effect of F30066 on the liver and kidney functions of uninfected and infected rabbits six weeks after the cercarial infection of Schistosoma japonicum. The experimental results indicate that the drug causes some damages to the liver and the kidney, but the damages are reversible. The authors also observed the normal-value distributions of several useful tests for liver and kidney func- tions in about 200 animal-times of rabbits.