| F30066对家兔肝肾功能的影响 |
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| 引用本文： | 席裕瑞,张应民,王翠英.F30066对家兔肝肾功能的影响[J].药学学报,1965,12(12):821-823. |
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| 作者姓名： | 席裕瑞 张应民 王翠英 |
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| 作者单位： | 中国医学科学院寄生虫病研究所,上海 |
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| 摘 要： | F30066, N-(isopropyl)-β-(5-nitro-2-furyl)-acrylamide, is a new oral drug for Schis- tosomiasis japonica. The present work studied the effect of F30066 on the liver and kidney functions of uninfected and infected rabbits six weeks after the cercarial infection of Schistosoma japonicum. The experimental results indicate that the drug causes some damages to the liver and the kidney, but the damages are reversible. The authors also observed the normal-value distributions of several useful tests for liver and kidney func- tions in about 200 animal-times of rabbits.
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| 收稿时间： | 1964-12-14 |
THE EFFECT OF F30066 ON THE LIVER AND KIDNEY FUNCTIONS OF RABBITS |
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| XI YU-RUI CHANG YING-MIN WANG CUI-YING.THE EFFECT OF F30066 ON THE LIVER AND KIDNEY FUNCTIONS OF RABBITS[J].Acta Pharmaceutica Sinica,1965,12(12):821-823. |
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| Authors: | XI YU-RUI CHANG YING-MIN WANG CUI-YING |
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| Abstract: | F30066, N-(isopropyl)-β-(5-nitro-2-furyl)-acrylamide, is a new oral drug for Schis- tosomiasis japonica. The present work studied the effect of F30066 on the liver and kidney functions of uninfected and infected rabbits six weeks after the cercarial infection of Schistosoma japonicum. The experimental results indicate that the drug causes some damages to the liver and the kidney, but the damages are reversible. The authors also observed the normal-value distributions of several useful tests for liver and kidney func- tions in about 200 animal-times of rabbits. |
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