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排序方式: 共有188条查询结果,搜索用时 15 毫秒
1.
Pregnancy by Assisted Reproductive Technology Is Associated with Shorter Telomere Length in Neonates
Toshiko Minamoto Kentaro Nakayama Tomoka Ishibashi Masako Ishikawa Kohei Nakamura Hitomi Yamashita Kamrunnahar Shanta Hossain Mohammad Mahmud Sultana Razia Kouji Iida Gyosuke Sakashita Tsukasa Nakamura Hideyuki Kanda Satoru Kyo 《International journal of molecular sciences》2020,21(24)
Telomere length (TL) influences the development of lifestyle-related diseases, and neonatal TL may influence their prevalence. Various factors have been reported to affect neonatal TL. Although the fetus is exposed to multiple conditions in utero, the main factors affecting the shortening of neonatal TL are still not known. In this study, we sought to identify factors that influence fetal TL. A total of 578 mother-newborn pairs were included for TL analysis. TL was measured in genomic DNA extracted from cord blood samples using quantitative PCR. The clinical factors examined at enrollment included the following intrauterine environmental factors: maternal age, assisted reproductive technology (ART) used, body mass index (BMI), gestational diabetes mellitus (GDM), maternal stress, smoking, alcohol consumption, preterm delivery, small-for-gestational-age, neonatal sex, and placental weight. Univariate and multivariate regression analyses were used to verify the relationship between neonatal TL and these clinical factors. The median neonatal TL to single-copy gene ratio was 1.0. Pregnancy with ART was among the 11 factors associated with shorter neonatal TL. From multiple regression analysis, we determined that neonatal TL was significantly shorter for pregnancies in the ART group than in the other groups. We conclude that pregnancy with ART is associated with shorter neonatal TL. 相似文献
2.
Chingszu Lin Zhifeng Huang Masako Kanai-Pak Jukai Maeda Yasuko Kitajima Mitsuhiro Nakamura 《Advanced Robotics》2019,33(6):278-292
With the number of hospital stays increasing, nurses require more training to handle a variety of patients. However, time for training in nursing schools is limited, and students lack the opportunity to practice on a diverse variety of patients. Using a robot to simulate actual patients, this study observes the learning transfer effect of practice on practice-similar and practice-dissimilar skills from one patient to another, and investigates which types of practice suit which kinds of training. An experiment was conducted by administering a pre-test, practice, a post-test, and a transfer test to two groups (N?=?8), each with different practice-related skills. The evaluation used a checklist covering required skills that were either similar or dissimilar across groups, depending on their practice. The effect of practice can be observed through a comparison of skills similar to one group but dissimilar to the other. The results show that practice facilitates learning transfer on similar skills but not, or to a lesser degree, on dissimilar skills. Furthermore, if skills needed to handle given symptoms are unfamiliar or inaccessible to students, practice related to those symptoms should be emphasized through simulated training with robots. 相似文献
3.
Theories of the biaxial tensile properties, the uniaxial tensile properties, and the shear-deformation properties of plain-weave fabrics are presented in a general form, a simplified stereo-model of the structure of plain-weave fabrics being used throughout these theories. In the first part of this series, the biaxial tensile-deformation theory is presented with the aid of the model, and the forces required to stretch the fabric along the warp and weft directions at the same time are theoretically calculated from the properties of yarns and from the structure of the fabrics. In this biaxial theory, both warp and weft yarns are assumed to be perfectly flexible, and the forces caused by yarn-bending are ignored. The compressibility of the yarn under the action of a lateral compressive force is also introduced into the theory, and it is shown that the compressive properties of yarns have a great influence on the tensile properties of the fabrics. 相似文献
4.
Wool fibres are subjected to severe mechanical actions during the worsted-spinning process, especially on a high-speed system. The loss of crimp and crimp recovery of single wool fibres are examined by measuring the crimp shrinkage of single fibres and the bulkiness of fibre bundles sampled at various stages in a commonly used worsted-spinning system. It is found that the crimp and crimp recovery of single fibres gradually decrease with progress through the spinning system, the reduction being particularly noticeable during carding. Fibre bundles with a high crimp level showed greater bulkiness. 相似文献
5.
A mechanical model of the 2/2-twill weave is presented in order to investigate the tensile properties of this weave under biaxial extension. The theory predicts that the compressional deformations of the warp and the weft at their cross-over point produce a superior effect on the tensile properties of the weave, especially in the relatively small-extension state. Experimental investigation to examine the accuracy of this theory is also reported, and good agreement between the theory and the experimental result is demonstrated. 相似文献
6.
Kazumitsu Nawata Masako Ii Aya Ishiguro Koichi Kawabuchi 《Mathematics and computers in simulation》2009
We analyze the length of hospital stays of patients hospitalized for cataract and related diseases (Diagnosis Related Groups (DRG) 2041) in Japan, utilizing the data pertaining to 3436 patients on whom one-eye lens operations are performed. We use the discrete-type proportional hazard model to analyze variables that may affect the length of stay. 相似文献
7.
The purpose of the study was to investigate what kind of factors determine the degree of difficulty for chimpanzees (Pan troglodytes) when they imitate actions. Five adult chimpanzees were instructed to perform 48 arbitrary manipulatory actions consisting of different bodily motor patterns and object directionality. Results showed that actions in which an object is directed toward another external location (another object and one's own body) were easier to perform than those that involved manipulating a single object alone. Actions involving unfamiliar motor patterns were more difficult to perform than those involving familiar motor patterns that were already present in the subject's repertoire. Error responses were characterized as perseverative repetition of previously instructed actions. These findings suggest that chimpanzees find the directionality of manipulated objects a more salient cue than details of the demonstrator's body movements performing the manipulation. (PsycINFO Database Record (c) 2010 APA, all rights reserved) 相似文献
8.
9.
Zebrowitz Leslie A.; Kikuchi Masako; Fellous Jean-Marc 《Canadian Metallurgical Quarterly》2010,98(2):175
The authors used connectionist modeling to extend previous research on emotion overgeneralization effects. Study 1 demonstrated that neutral expression male faces objectively resemble angry expressions more than female faces do, female faces objectively resemble surprise expressions more than male faces do, White faces objectively resemble angry expressions more than Black or Korean faces do, and Black faces objectively resemble happy and surprise expressions more than White faces do. Study 2 demonstrated that objective resemblance to emotion expressions influences trait impressions even when statistically controlling possible confounding influences of attractiveness and babyfaceness. It further demonstrated that emotion overgeneralization is moderated by face race and that racial differences in emotion resemblance contribute to White perceivers’ stereotypes of Blacks and Asians. These results suggest that intergroup relations may be strained not only by cultural stereotypes but also by adaptive responses to emotion expressions that are overgeneralized to groups whose faces subtly resemble particular emotions. (PsycINFO Database Record (c) 2010 APA, all rights reserved) 相似文献
10.
Kiyoshi Kawai Setsuko Takato Masako Ueda Nao Ohnishi Chotika Viriyarattanasak Kazuhito Kajiwara 《International Journal of Food Properties》2017,20(7):1500-1510
The effects of fatty acid, monoacylglycerol, and polyglycerol fatty acid ester with varying chain length in their acyl chains on the extent of complex formation (complex index) and in vitro enzymatic digestibility of gelatinized potato starch were investigated. The complex index increased with increase in the concentration of the ligands (fatty acid, monoacylglycerol, and polyglycerol fatty acid ester), with the plateau in the complex index value depending on the type of ligands. In comparison of complex index among fatty acid-samples, the complex index maximum increased as the chain length increased up to octanoic acid and then decreased. In comparison of complex index among fatty acid-, monoacylglycerol-, and polyglycerol fatty acid ester-samples at each acyl chain, the complex index maximum followed the order polyglycerol fatty acid ester > monoacylglycerol > fatty acid. Fatty acid, monoacylglycerol, and polyglycerol fatty acid ester with long acyl chains greatly reduced the enzymatic hydrolysis of starch. Polyglycerol fatty acid ester with palmitic acid chains was the strongest inhibitor of starch hydrolysis, suggesting that further complex formation may occur during the hydrolysis of gelatinized starch (enzyme-annealing). 相似文献