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To determine 17 elements in lung carcinomatous and pericarcinomatous tissues by inductively coupled plasma mass sepctrometry (ICP-MS), samples were digested using HNO3 and HClO4. Rhodium was used as an internal standard element. Reference materials of GBW(E)080193 Bovine Hepar and GBW09101 Human Hair were analyzed by the described method. The analytic values of two reference materials are accorded with the reference values. The recovery rates are 90%-110%. The precisions of the method are most below 10%. The concentrations of seventeen elements in lung carcinomatous and pericarcinomatous tissues are remarkable different. Seventeen elements in human lung tissue can be determined rapidly, simply, accurately by ICP-MS. 相似文献
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“Elementomics” is proposed here since all the lives are constructed by the elements listed in the Periodic Table. 55 elements in lung cancerous and pericancerous tissues were determined and statistically analyzed. Some regularities, such as specific storage and specific correlation, have been found in both tissues. These results in the elementomes could be explained with the aid of those existed in the genomes, proteomes, metabollomes and metalomes. 相似文献
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中国成年男子全血及器官组织中稀土元素分布模式 总被引:1,自引:0,他引:1
在我国四个不同膳食类型地区(河北省、山西省、江苏省和四川省)采集16例急死正常成年男子尸体的心脏血、肝脏、脾脏、睾丸、肋骨5种器官组织样品。采用湿法消解,用ICP-MS法测定其15种稀土元素分量,它在器官组织中的蓄积浓度分别为肝(318.8ng/g)>肋骨(107.9ng/g)>睾丸(30.2ng/g)>脾脏(24.6 ng/g)>血(3.3 ng/mL);除血和肋骨中的La、Ce外,其余13种稀土元素在上述组织器官的分布模式均符合奥多-哈尔金斯定律;经球粒陨石归一化处理稀土元素在组织器官中的分布模式均存在轻稀土富集重稀土亏损(LaN/SmN>1和GdN/YbN>1)。 相似文献
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为了全面分析人体内稀土元素通过膳食摄取、血液蓄积、尿粪排出之间的关系,应用等离子体质谱法测定成人全血、膳食、尿样及粪便中轻稀土元素含量,比较4个不同膳食类型的城市人体摄取轻稀土元素的差异,并对相同个体的膳食、全血、尿样及粪便中的轻稀土元素进行相关性分析。分别在天津、成都、镇江、太原4个城市采集30名健康成年男性的全血、72 h 膳食、72 h尿样和72 h粪便,膳食、尿样和粪便做冷冻干燥处理后经湿法消解,并采用电感耦合等离子体质谱法测定轻稀土元素含量。4城市采样人体中的稀土含量由高至低依次为粪便、膳食、血液,尿液,但上述样品在4城市人群之间没有显著性差异;同体血、膳食和粪便中轻稀土元素的分布特征符合自然分布特征规律,但尿样中的Sm存在正异常。 相似文献