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1.
Food Science and Biotechnology - The process of cellular senescence is rapidly emerging as a modulator of organismal aging and disease. Targeting the development and removal of senescent cells is... 相似文献
2.
Farida khan Naeem A Israf Ud Din T. Saeed Mshari A. Alotaibi Abdulrahman I. Alharthi Asad Habib Tabassum Malik 《Ceramics International》2021,47(4):4749-4757
In the present study, hexagonal boron nitride (h-BN) was synthesized from boric acid and melamine by thermal annealing method in a nitrogen atmosphere. The pure h-BN was used as an efficient sorbent for the uptake of Cd2+ ions from the solution phase. The kinetics and sorption studies of metal ions onto the h-BN were carried out in batch adsorption experiments at different temperature, time, pH, sorbent dosage, and concentration of metal ions. The optimum pH for the removal of the Cd2+ ions was found to be pH 7. The effect of temperature showed that the process of Cd2+ sorption remained endothermic in the range of 298 K–328 K. The Lagergren's first and Ho's second kinetic models were tested to interpret the adsorption kinetic data, however the present data was explained well by Ho's model for kinetics. The thermodynamic perameters ΔG, ΔS and ΔH were determined using the available adsorption data at different temperatures. The physicochemical properties of the synthesized product were also characterized before and after adsorption by different analytical techniques like FT-IR, TGA, XRD and Point of Zero Charge (PZC). The morphology of the surface was analyzed with the help of Scanning Electron Microscopy. The h-BN proved to be an efficient adsorbent for the uptake of the Cd2+ ions from aqueous media. 相似文献
3.
Nirupaplava Metta Rohit Ramachandran Marianthi Ierapetritou 《American Institute of Chemical Engineers》2021,67(2):e17095
Identification of feasible region of operations in multivariate processes is a problem of interest in several fields. This is particularly challenging when the process model is black-box in nature and/or is computationally expensive, as analytical solutions are not available and the number of possible model evaluations is limited. An efficient methodology is required to identify samples where the model is evaluated for developing a computationally efficient surrogate model. In this work, an artificial neural network based surrogate model is proposed which is integrated with a statistical-based approach (Jack-knifing) to estimate the variance of the surrogate model prediction. This allows implementation of an adaptive sampling approach where new samples are identified close to the feasible region boundary or in regions of high prediction uncertainty. The proposed approach performs better than a previously published kriging based method for different dimensionality case studies. 相似文献
4.
The introduction of multiple heterogeneous interfaces in a ceramic is an efficient way to increase its thermal resistance. Novel porous SiC–SiO2–Al2O3–TiO2 (SSAT) ceramics were fabricated to achieve multiple heterogeneous interfaces by sintering equal volumes of SiC, SiO2, Al2O3, and TiO2 compacted powders with polysiloxane as a bonding phase and carbon as a template at 600 °C in air. The porosity could be controlled between 66% and 74% by adjusting the amounts of polysiloxane and the carbon template. The lowest thermal conductivity (0.059 W/(m·K) at 74% porosity) obtained in this study is an order of magnitude lower than those (0.2–1.3 W/(m·K)) of porous monolithic SiC, SiO2, Al2O3, and TiO2 ceramics at an equivalent porosity. The typical specific compressive strength value of the porous SSAT ceramics at 74% porosity was 3.2 MPa cm3/g. 相似文献
5.
Mandeep Singh Ramdev Rohit Bajaj Ruchika Gupta 《New Review of Information Networking》2020,25(1):71-82
ABSTRACT Wireless Interoperability for Multiple Access (WiMAX) is one of the emerging fields of high-speed wireless communication that has enormous capabilities due to its range and the connection speed. Like wireless local area networks (LANs), WiMAX networks implement multiple quality of service (QoS) frameworks at the Media Access Control (MAC) level for assured data, voice, and video services. The question of ensuring QoS is basically how to distribute available resources to users in order to satisfy QoS parameters such as latency, jitter and throughput requirements. IEEE 802.16 standard does not have any particular guidelines on scheduling of incoming and outgoing data. This has caught the attention of researchers working on WiMAX. This article discusses the various issues in WiMAX along with a classification of various scheduling approaches based upon the type of scheduler for the sake of better understanding the scheduling problem and analyzing various available theories. 相似文献
6.
Multimedia Tools and Applications - In this paper, we propose a novel interpolation and a new reversible data hiding scheme for upscaling the original image and hiding secret data into the... 相似文献
7.
Pattern Analysis and Applications - This paper presents a reliable and real-time method to detect pedestrians in image scenes that can vary greatly in appearance. To achieve greater reliability in... 相似文献
8.
Chensen Ding Xiangyang Cui Rohit R. Deokar Guangyao Li 《Numerical Heat Transfer, Part A: Applications》2018,73(10):667-684
This article develops an isogeometric independent coefficients (IGA-IC) reduced order method for transient nonlinear heat conduction analysis. Herein, we first exactly represent the geometric model via isogeometric analysis (IGA), and therein provide an accurate solution for the semi-discretized equations. Next, our proposed GSSSS-1 time-stepping framework is employed to solve the transient nonlinear temperature in space and time domains. We advance our independent coefficients (IC) reduced order method to efficiently solve IGA-based transient nonlinear heat conduction problems. We extend the IC method to significantly reduce the original full IGA-discretized formulations and calculate the reduced equilibrium formulations in each Newton–Raphson iteration. Thereby, hugely improving the efficiency and guaranteeing the accuracy simultaneously. Illustrative numerical examples validate this proposed IGA-IC method is reliable, accurate, and efficient; especially, the larger the scale of the problem, the more advantages the proposed IGA-IC will inherit. 相似文献
9.
Md. Abdur Rahim Shamim Mahbub Md. Kamrul Islam Sk. Md. Ali Ahsan Shahed Rana Malik Abdul Rub Anish Khan Md. Anamul Hoque 《Journal of surfactants and detergents》2020,23(2):457-470
Conductometric and cloud point (CP) measurement studies have been performed to investigate the interaction of tetradecyltrimethylammonium bromide (TTAB) and Triton® X-100 (TX-100) with ciprofloxacin hydrochloride (CFH) in different solvents over the temperature range of 295.15–315.15 K. CFH is used for the treatment of various bacterial infections. The observed critical micelle concentration (CMC) values of TTAB were found to be reduced in the presence of electrolytes (Na2SO4/Na3PO4), and this reduction proceeds with the elevation of salt concentration. The order of the CMC of TTAB follows the trend: > >. The observed CMC values of TTAB were found to increase with increasing temperature and decrease with increasing concentration of CFH in aqueous medium. The values of Gibbs free energy of micellization () for the TTAB/TTAB + CFH mixture were found to be negative, implying spontaneous micellization. The estimated CP of TX-100 decreases with increasing concentration of TX-100 in aqueous medium. The CP values first decrease with increasing concentration of CFH and then increase at higher concentration of CFH almost in all cases investigated. The values of free energy of clouding were found to be positive in all cases studied implying that phase separation of TX-100 was nonspontaneous. The other thermodynamic parameters associated with the micellization of TTAB and the phase separation of TX-100 were estimated and explained. 相似文献
10.
Pradum Pundlikrao Ige Rohit Ravindra Badgujar Pankaj Padmakar Nerkar Hitendra Shaligram Mahajan Raju Onkar Sonawane Sanjay Javarilal Surana 《Particulate Science and Technology》2018,36(5):583-591
Drug which shows extensive first pass effect is difficult task that, needs to be solved by formulators in the pharmaceutical science. The low oral bioavailability (49%) of flutamide may be due to poor wettability, low aqueous solubility and extensive first pass effect. The aim of present investigation was to prepare flutamide loaded microspheres and incorporate it into suppositories for rectal delivery to avoid first pass effect and enhance residence time. Flutamide loaded mucoadhesive microspheres of Ocimum Basilicum mucilage (OBM) were prepared using spray drying and characterized by percent production yield, encapsulation efficiency, particle size, zeta potential, polydispersity index, DSC, SEM, XRPD, in vitro drug release and stability studies. Moreover, ex vivo mucoadhesion was investigated using falling liquid film technique to determine the adhesion of microspheres to sheep rectal mucosa. The microspheres had nearly spherical shape and size about 2.53?μm. The encapsulation efficiency and mucoadhesion of optimized formulation MBF10 were found to be 69.6?±?2.3% and 89.01?±?2.18%, respectively. Percent CDR of optimized flutamide loaded mucoadhesive microspheres was found to be 88.7?±?1.3 at 7?h. In conclusion, OBM microparticles based suppository could be used to deliver drug through rectal delivery. 相似文献