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排序方式: 共有386条查询结果,搜索用时 31 毫秒
1.
Raquel Cano Jos L. Prez Liss Angarita Dvila ngel Ortega Yosselin Gmez Nereida Josefina Valero-Cedeo Heliana Parra Alexander Manzano Teresa Isabel Vliz Castro María P. Díaz Albornoz Gabriel Cano Joselyn Rojas-Quintero Maricarmen Chacín Valmore Bermúdez 《International journal of molecular sciences》2021,22(9)
Non-alcoholic fatty liver disease (NAFLD) is considered the most common liver disorder, affecting around 25% of the population worldwide. It is a complex disease spectrum, closely linked with other conditions such as obesity, insulin resistance, type 2 diabetes mellitus, and metabolic syndrome, which may increase liver-related mortality. In light of this, numerous efforts have been carried out in recent years in order to clarify its pathogenesis and create new prevention strategies. Currently, the essential role of environmental pollutants in NAFLD development is recognized. Particularly, endocrine-disrupting chemicals (EDCs) have a notable influence. EDCs can be classified as natural (phytoestrogens, genistein, and coumestrol) or synthetic, and the latter ones can be further subdivided into industrial (dioxins, polychlorinated biphenyls, and alkylphenols), agricultural (pesticides, insecticides, herbicides, and fungicides), residential (phthalates, polybrominated biphenyls, and bisphenol A), and pharmaceutical (parabens). Several experimental models have proposed a mechanism involving this group of substances with the disruption of hepatic metabolism, which promotes NAFLD. These include an imbalance between lipid influx/efflux in the liver, mitochondrial dysfunction, liver inflammation, and epigenetic reprogramming. It can be concluded that exposure to EDCs might play a crucial role in NAFLD initiation and evolution. However, further investigations supporting these effects in humans are required. 相似文献
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Increased global competition and resource scarcity drives industrial companies to cut costs. Energy can be a significant component of such cuts, particularly for energy-intensive companies. Improving energy efficiency in industry is complex, as it pertains to various energy-using processes that are heavily intertwined. One such process is the compressed air system (CAS), which is used in most industrial companies worldwide. Since energy efficiency improvement measures for various types of energy-using processes differ, technology-specific measures might encounter different barriers to and drivers for energy efficiency. The same applies to the non-energy benefits (NEBs) related to energy efficiency improvement measures; since measures vary between various energy-using processes, the perceived NEBs might be different as well. The aim of this paper is to study the barriers to, drivers for and NEBs of CAS energy efficiency improvement measures from the perspectives of three actors. Carried out as an interview study combined with a questionnaire, the paper merges the perspectives of users, audit experts and suppliers of CASs. The results showed that the major barriers are related to the investment, or are of an organisational character, and that organisational and economic factors seemed to be important for making positive decisions on energy efficiency investments and measures in CASs. Major NEBs for CASs include productivity gains and the avoidance of capital expenditures. The results of this study also address the importance of having a comprehensive approach to recognise additional effects of energy efficiency improvements in CASs. 相似文献
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R. Parra A. Covelo R. J. Ramírez A. Tejeda A. Ortega 《Journal of Adhesion Science and Technology》2018,32(12):1341-1358
Preservation of archaeological artefacts after their removal from saline media is a difficult task due to the chloride content of the oxide layers which are unstable in atmospheric conditions, especially if the relative humidity exceeds 85%. For this reason, removal of chlorides from rust layers is one of the priorities of conservationists or restorers of historical artefacts. However, removal of chloride ions is not an easy procedure because of the many considerations involved in the process. In this research, artificially pre-rusted iron samples and an actual historical cannonball were subject to a dechlorination process in a potassium hydroxide solution to measure constant chloride release in a bulk solution. After the chloride removal process, a commercial protective layer was applied to the rust for stabilization purposes. It was calculated that the kinetics of the dechlorination process is driven by diffusion behaviour following Fick’s second law. When this diffusion process prevails, the dechlorination extraction affects the integrity of rust layers as is demonstrated with scanning electron microscopy and X-ray diffraction analyses. It was proven that the chloride removal procedure causes the studied iron layers to stiffen, provoking superficial modification and, in some cases, fractures of the rust. By means of electrochemical impedance spectroscopy it was calculated that the magnitude of the positive effect of the dechlorinated samples depends on the protective features of the rust. Therefore, this research reveals that an efficient chloride removal procedure depends on the electrochemical properties of the dechlorination process and the initial morphology of the iron rust. 相似文献
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Neural Computing and Applications - In electric vehicles (EVs) with multiple motors, torque vectoring (TV) control can effectively enhance the cornering response and safety. Moreover, TV systems... 相似文献
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Bezene Detection: Deep Cavitand Self‐Assembled on Au NPs‐MWCNT as Highly Sensitive Benzene Sensing Interface (Adv. Funct. Mater. 26/2015) 下载免费PDF全文
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Javier Marcos Íigo de la Parra Miguel García Luis Marroyo 《Progress in Photovoltaics: Research and Applications》2016,24(5):680-691
A model to simulate the fluctuations generated by a fleet of dispersed photovoltaic (PV) plants solely based on irradiance data measured at one single location is proposed. This simple model has been satisfactorily tested to quantify the power variability of a generic PV fleet, simply by defining two parameters: mean PV plant size and the number of plants in the PV fleet. Specifically, the model provides series of simulated power outputs that may be used in the grid operator simulation programmes, reproducing critical parameters, such as daily maximum fluctuation or the reserves required to offset these fluctuations. The model is created and validated against experimental 1‐s data collected throughout 2013 at six PV plants in Spain dispersed over 1100 km2, totaling 17 MWp. Likewise, the model has been succesfully tested against another irradiance dataset, four sites across the state of Colorado, USA, and spread over 2400 km2. Copyright © 2015 John Wiley & Sons, Ltd. 相似文献
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