鼻咽癌颈转移淋巴结的多普勒血流信号特征

目的研究鼻咽癌颈转移淋巴结的彩色多普勒血流信号特征.材料与方法鼻咽癌伴颈淋巴结转移患者52例共134枚颈转移淋巴结,在接受治疗前行彩色多普勒血流检查,分析其血流信号特征和血供强度与淋巴结大小、部位的关系.结果鼻咽癌颈转移淋巴结的动脉血管多分布在淋巴结的周边,血流阻抗(RI)高;淋巴结血流强度的分布因淋巴结部位、大小的变化而不同,大淋巴结较小淋巴结血供丰富;中、下颈淋巴结较上颈淋巴结血供丰富.结论鼻咽癌颈转移淋巴结以周边型高阻血流信号为主.血供强度与淋巴结大小、部位有关.     

Usefulness of 201Tl SPECT in the predication of mediastinal lymph nodes metastasis in patients with non small cell lung carcinoma (NSCLC)

Predictivity of mediastinal lymph nodes metastasis of 201Tl SPECT were examined before operation in 113 patients with non-small cell lung cancer (69 adenocarcinoma, 31 squamous cell carcinoma, 10 large cell carcinoma, 2 bronchiolo-alveolar carcinoma, 1 neuroendocrine cell carcinoma). Patients were classified into two groups, with or without lymph nodes metastasis according to the pathological diagnosis. We calculated parameters of 201Tl SPECT early ratio, delayed ratio, retention index (RI) and maximal diameters. In addition, we calculated optimal cut-off value of RI to estimate the mediastinal lymph nodes metastasis. Mediastinal lymph nodes metastasis was confirmed pathologically in 62 patients. ER and DR did not show any statistical significance between two groups. Maximal diameters of primary tumor were also comparable between two groups. RI was significantly higher in mediastinal lymph node metastasis positive group compared to that in mediastinal lymph node metastasis negative group. The sensitivity (Sen), specificity (Spe), positive predictive value (PPV), negative predictive value (NPV) and accuracy (Acc) of 201Tl SPECT were 82.2%, 82.3%, 85.0%, 79.2% and 82.3%. These parameters were similar of higher than 72.6%, 82.4%, 83.3%, 71.2% and 77.0% of chest CT. The RI of 201Tl SPECT was useful tool for predicting lymph nodes metastasis in non-small cell lung cancer. The optimum cut-off value of RI in the prediction of mediastinal lymph nodes metastasis was 35%. We should take into account of upstaging in cases with higher RI (>35%).     

血管内皮生长因子在贲门癌中的表达和临床意义

目的　探讨贲门癌血管内皮生长因子 (VEGF)、血管生成与贲门癌临床病理特点的关系。方法　采用免疫组织化学技术 ,检测 35例贲门癌组织VEGF蛋白表达和微血管密度 (MVD)。分析VEGF和MVD的关系及其与贲门癌组织学分型、浸润深度、淋巴结转移和预后的关系。结果　VEGF阳性者MVD值显著高于阴性者 ,VEGF及MVD与贲门癌浸润深度 ,淋巴结转移密切相关 ,与组织学分型也有明显相关性。结论　VEGF与贲门癌的血管生成密切相关 ,对其生长和浸润转移起促进作用 ,VEGF可作为贲门癌生物学行为的指标之一。     

SPECT/CT在cN0期甲状腺乳头状癌前哨淋巴结定位中的应用价值

目的 评价SPECT/CT淋巴显像检测cN0期甲状腺乳头状癌（PTC）患者前哨淋巴结（SLN）的价值。 方法 选取2017年4月至11月在山西医科大学第一医院住院的16例淋巴结阴性（cN0）期PTC患者,其中男性2例、女性14例,年龄（47.0±8.4）岁,于手术前行99Tcm-硫体胶（99Tcm-SC）平面显像和SPECT/CT显像检测SLN。手术中使用γ探测仪探测放射性“热点”。将手术切除的SLN及颈部清扫标本进行病理学检查。 结果 16例患者术前 99Tcm-SC平面显像检出SLN 14例,检出率为87.50% （14/16）。术前99Tcm-SC平面显像、SPECT/CT显像分别检出31枚和35枚SLN。术中γ探测仪探测到SLN 13例,共计37枚,检出率为81.25% （13/16）。γ探测仪探测SLN数目与SPECT/CT淋巴显像数目有4例不一致,12例一致,两种方法的一致率为75% （12/16）。病理结果显示,15例患者有淋巴结转移,占93.75% （15/16）。SPECT/CT检测SLN的灵敏度为86.67% （13/15）、准确率为81.25% （13/16）、假阴性率为13.33% （2/15）。 结论 术前SPECT/CT淋巴显像能有效探测cN0期PTC患者的SLN,准确预测颈部淋巴结的转移情况。     

甲状腺乳头状癌淋巴结转移诊疗现状研究

甲状腺乳头状癌（PTC）是甲状腺癌最常见的组织病理学类型,其淋巴结转移影响患者的预后。目前PTC的淋巴结转移机制尚不明确,其诊断方法包括超声、细针穿刺活检、CT、MRI、SPECT/CT、PET/CT等,但特异度及灵敏度均不高,联合使用可以提高检出率。PTC淋巴结转移首选的治疗方式是手术。目前PTC淋巴结转移早期综合诊断及有效治疗是改善和提高PTC患者生活质量的难点。笔者就PTC淋巴结转移的诊疗现状及研究进展进行综述。     

131I SPECT/CT在分化型甲状腺癌术后淋巴结转移中应用价值的研究进展

分化型甲状腺癌（DTC）是最常见的内分泌系统恶性肿瘤,早期易发生淋巴结转移。131I全身显像联合SPECT/CT（简称131I SPECT/CT）常可发现残留和（或）漏诊的淋巴结转移灶,可能会改变患者的术后再分期及危险度分层,从而影响后续的手术或131I治疗的方式选择。131I治疗是DTC术后颈部淋巴结转移的有效治疗方法之一,而131I SPECT/CT可以诊断淋巴结转移灶。笔者对131I SPECT/CT在DTC术后淋巴结转移的诊断及治疗中的应用价值进行综述。     

甲状腺乳头状癌淋巴结转移的CT特征及临床意义

目的：探讨甲状腺乳头状癌淋巴结转移的CT特征性表现,提高甲状腺乳头状癌淋巴结转移的诊断正确率,为外科手术方案和手术范围选择提供可靠依据。方法回顾分析经手术病理证实的共334例甲状腺乳头状癌患者的CT影像资料,对其中141例发生颈部淋巴结转移的病例进行统计学分析。结果141例患者中包括仅有中央区（Ⅵ区）淋巴结转移79例,CT诊断符合为60例;中央区及侧颈区（Ⅱ～Ⅴ区）均转移者62例, CT诊断符合51例。结果采用χ2检验。102例淋巴结密度、强化程度与甲状腺癌相似,其中23例伴有囊变坏死,14例伴有颗粒状钙化灶,7例并发喉返神经侵犯或气管、血管侵犯。结论甲状腺癌转移淋巴结好发部位为中央区;但侧颈区亦同样常常有转移,应高度重视。转移淋巴结的CT扫描特征：淋巴结明显强化,强化程度与甲状腺乳头状癌保持一致,可发生囊性变或坏死,以及出现颗粒状钙化灶,CT检查对临床手术方案制定具有重要指导意义。     

~(18)F-FDG符合线路显像在喉癌中的应用价值

目的:探讨18F-FDG符合线路显像在喉癌中的应用价值。方法:30例经病理证实的喉癌患者术前行18F-FDG双探头符合线路显像及CT检查。其中28例行手术治疗,以术后病理检查结果作为"金标准",比较18F-FDG符合线路显像及CT检查在原发肿瘤、淋巴结及远处转移(TNM)中的价值。结果:18F-FDG与CT探测淋巴结病变的灵敏度为75.00%和62.50%,特异性78.26%和43.48%,准确性76.36%和54.55%,阴性预测值69.23%和45.45%,阳性预测值82.76%和60.61%,其中特异性、准确性差异有统计学意义(P0.05)1。8F-FDG符合线路显像发现2例有远处转移,改变了治疗方案。结论:18F-FDG符合线路显像在喉癌术前分期和治疗方案的制定中具有较好的临床应用价值。     

Lymphatic drainage routes of the gastric cardia visualized by lymphoscintigraphy.

This study was undertaken to assess the feasibility of lymphoscintigraphy of the gastric cardia and to identify the incidence of paraesophageal lymphatic drainage, precluding total gastrectomy with esophagojejunostomy as a potentially curative therapy for gastric cardia cancer. METHODS: Ten patients scheduled for esophagectomy with high-grade dysplasia or with esophageal cancer at least 3 cm above the esophagogastric junction were enrolled in this study. Preoperatively, 111 MBq of(99m)Tc-labeled nanocolloid (n = 5) or sulfur colloid (n = 5) were injected into the submucosa of the tumor-free cardia. Subsequently, lymphoscintigraphy in combination with CT was obtained. Locoregional lymph node stations were measured for radioactivity by a gamma-probe intraoperatively and ex vivo in the resection specimen. RESULTS: In each patient, at least 1 radioactive lymph node station was detected. In total, 42 radioactive lymph node stations were detected by gamma-probe. Of those 42 areas, 38 (90%) were visible at preoperative lymphoscintigraphy. In the group of 5 patients in whom nanocolloid was used, a median of 2 (range, 1-4) node stations per patient was identified, whereas when sulfur colloid was administered a median of 6 (range, 4-8) active lymph node stations per patient could be detected (P < 0.002). Paraesophageal drainage was identified in 1 patient. CONCLUSION: Lymphoscintigraphy of the gastric cardia is feasible and can accurately determine the location of radioactive lymph nodes. Early paraesophageal lymphatic drainage is rare.     

Evaluation of the "N" factor in nonsmall cell lung cancer. Correlation between computerized tomography and pathologic anatomy

PURPOSE: To evaluate the role of CT in identifying other morphological signs of metastatic lymph node involvement from non small cell bronchogenic carcinoma. This is done to improve N staging, a critical step in this disease. In fact, since diameter is the only criterion used to distinguish normal form abnormal lymph nodes, medistinal CT only has 80% diagnostic accuracy. MATERIAL AND METHODS: 137 patients with known or suspected lung cancer were examined with Helical CT during early and late arterial phases (2 min delay, 3 mm thickness, 5 mm interslice gap) to depict node characteristics. Mediastinal lymph nodes, located according to the American Thoracic Society mapping, were considered normal when they were not visible or, if visible, less than 1 cm in diameter and of homogeneous density; lymph nodes over 1 cm in diameter and homogeneous density were considered reactive. A lymph node was considered metastatic when, independent of size, the following signs were found: central hypodensity; hyperdense thin/thick rim, with nodules within; hyperdense strands or diffuse hyperdensity in perinodal adipose tissue. The tumor site was also considered. RESULTS: Seventy patients were excluded because they were inoperable. Sixty-five of the remaining 67 patients were operated on, 1 underwent mediastinoscopy and another one mediastinoscopy followed by surgery. Based on the above CT signs, 46 patients were staged as N0, 61 as N1 and 15 as N2. In 44/46 N0 patients there was agreement between anatomical and pathologic findings; 3 of the 44 patients had lymph nodes over 1 cm in diameter and with homogeneous density. Micrometastases to mediastinal lymph nodes (N2) were found at histology in 2/46 patients (CT false negatives). In the 6 N1 and the 15 N2 patients there was complete agreement between anatomical and pathologic findings; in particular, 9 N2 patients had lymph nodes less than 1 cm in diameter with signs of metastasis and 4 had lymph nodes over 1 cm in diameter with signs of metastasis and 2 had lymph nodes either over or less than 1 cm. In all N2 patients the tumor histotype and the mediastinal location were also considered relative to the lesion site. DISCUSSION: A closer correlation was found with node morphology and density than with size. Indeed, CT sensitivity, specificity and diagnostic accuracy were 97, 100 and 97%, respectively, for the former versus 52, 93 and 77% for the latter. Adenocarcinoma was the predominant histotype (70.5%) in N2 patients. Metastases to node region 4 were predominant in right upper lobe carcinomas while node region 5 was predominant in left upper lobe lesions. CONCLUSIONS: Other criteria can be associated with size to improve CT diagnostic accuracy in N staging. Technique optimization plays a major role particularly in the late, thin slice, examination phase.     

Regional lymph node metastasis in gastric cancer: evaluation with endoscopic US.

Endoscopic ultrasound (EUS) was performed in 83 patients with gastric cancer to evaluate regional lymph node metastasis. Histopathologic findings were compared with preoperative EUS findings in a total of 1,519 resected lymph nodes. In lymph node staging, the prevalence of metastatic adenopathy was 31.3% (26 of 83 patients); EUS had an accuracy of 83.1% (69 of 83 patients), sensitivity of 53.8% (14 of 26 patients), specificity of 96.5% (55 of 57 patients), positive predictive value of 87.5% (14 of 16 patients), and negative predictive value of 82.1% (55 of 67 patients). The greater the maximum diameter of the node with metastasis, or the larger the ratio of the metastatic area to the cross-sectional area of the node, the higher the detection rate. In tumors classified on the basis of depth of invasion according to the 1987 TNM system, the rate of detection of metastasis in individual nodes was 0% in pT1 tumors (none of five nodes), 20% in pT2 tumors (17 of 85 nodes), 29% in pT3 tumors (20 of 70 nodes), and 10% in pT4 tumors (three of 31 nodes). It is concluded that the most important use of EUS will be in diagnosis of regional lymph node metastasis.     

胃癌18F-FDG PET/CT影像学表现与临床病理的相关性研究

目的 探讨胃癌18F-氟脱氧葡萄糖（FDG） PET/CT影像学表现与临床病理的相关性。 方法 回顾性分析2011年10月至2016年6月在福建省肿瘤医院行PET/CT检查并接受手术治疗的101例胃癌患者的临床病理资料,其中男性73例、女性28例,年龄25~81（59.74±11.39）岁。分析PET/CT原发灶的最大标准化摄取值（SUV_max）、厚度及淋巴结转移等情况,以性别、年龄、原发灶部位、原发灶长径、病理类型及分化程度、TNM（肿瘤、结节、转移）分期及临床分期为分组条件,采用独立样本t检验、单因素方差分析评价各组间SUV_max的差异,采用Pearson相关性分析评价SUV_max与原发灶大小之间的关系。筛选有统计学差异的指标纳入多因素Logistic回归分析,评价淋巴结转移与各因素之间的关系。 结果 101例胃癌患者原发灶的SUV_max在原发灶长径D（<4 cm:3.774±1.062,4 cm≤D<8 cm:6.552±3.695,≥8 cm:5.592±2.305）、原发灶部位（胃底及贲门:7.157±4.425,胃体:4.710±2.010,胃窦:6.137±3.069）和病理类型（印戒细胞癌:4.176±1.724,非印戒细胞癌:5.998±3.295）组间的差异有统计学意义（t=7.022, P=0.001;t=5.564,P=0.005;t=2.212,P=0.029）。Pearson 相关性分析结果表明,SUV_max与胃癌原发灶的长径、短径、厚度呈正相关（r=0.209,P=0.036;r=0.245,P=0.013;r=0.359,P<0.001）。PET/CT诊断胃癌淋巴结转移的灵敏度、特异度、准确率分别为71.3%（57/80）、81.0%（17/21）、73.3%（74/101）。多因素Logistic回归分析结果表明,T分期是淋巴结是否转移的独立相关因素（OR=12.648,95%CI:3.905~40.961, P<0.001）。 结论 胃癌原发灶SUV_max与肿瘤大小、部位、病理类型有关,T分期是预测淋巴结转移的独立因素。     

Correlative 201Tl SPECT, MRI and ex vivo 201Tl uptake in detecting and characterizing cervical lymphadenopathy in head and neck squamous cell carcinoma.

The value of SPECT with 201Tl chloride, in combination with MRI (particularly short inversion-time inversion recovery [STIR] sequences that suppress fat signals) to detect and characterize cervical lymphadenopathies (nodes > or = 1 cm), and ex vivo lymph node 201Tl uptake were studied in patients with squamous cell carcinoma of the head and neck. METHODS: Preoperative SPECT and MRI, displayed in similar planes, were compared with the histologic findings in 15 neck dissection specimens from 12 patients with squamous cell carcinoma of the head and neck (9 with unilateral and 3 with bilateral neck dissection). Results were evaluated topographically with regard to the lymph node compartments (levels) of the neck. In addition, in 8 of these patients, the 201Tl activity of dissected lymph nodes of 10 neck sides was measured immediately after surgery in a gamma counter and expressed as percentage of the injected dose per gram tissue (%ID/g). RESULTS: Sixty-two lymph node levels were evaluated histologically. The high sensitivity of MRI (92% versus 71% for 201Tl SPECT), which correctly detected lymph node involvement in 22 of 24 levels, and the high specificity of 201Tl SPECT (92% versus 71% for MRI), which correctly characterized as negative 35 of 38 lymph node levels without metastasis on histology, led to a combined 201Tl SPECT/MRI accuracy of 92%. 201Tl SPECT was particularly effective in excluding involvement in 9 tumor-free neck levels with pathologically enlarged lymph nodes on MRI but failed to confirm involvement in 5 other tumor-positive levels. Mean 201Tl uptake in 53 lymph nodes with confirmed histologic involvement was significantly higher than uptake in 145 tumor-free lymph nodes (0.0043+/-0.0022 %ID/g versus 0.0023+/-0.0014 %ID/g, P = 0.0001), muscle and fat tissue but clearly lower than salivary gland uptake. CONCLUSION: Although 201Tl SPECT is not sensitive enough to be used as an independent imaging modality for staging of the neck, its correlative application with MRI appears to be an accurate method for the assessment of regional spread in head and neck squamous cell carcinoma. The ability of 201Tl SPECT to characterize neck lymphadenopathies detected by MRI appears to be based on the difference in 201Tl concentration found in lymph nodes with and without tumor involvement.     

18F-FDG符合线路显像在乳腺癌诊断中的初步应用

目的研究18F-FDGSPECT/CT符合线路正电子显像在鉴别乳腺肿块性质和乳腺癌术前淋巴结转移分期中的应用价值。方法22例有乳腺肿块的女性患者行SPECT/CT符合线路18F-FDG显像,患者禁食6h以上,肘静脉注射18F-FDG185MBq～296MBq。静注60min后开始发射和X线CT透射扫描,然后进行符合线路PET连续采集30min。图像经X线衰减校正和有序子集最大期望值法(COSEM)叠代重建后,得到横断面、冠状面、矢状面三维断层图像及CT与FDGSPECT的融合图像。结果22例患者均通过手术切除治疗并获得病理结果。其中,乳腺癌16例,乳腺良性肿瘤6例。FDGSPECT诊断乳腺癌的敏感度、特异性和准确度分别是93.75%、100%和95.45%,明显高于乳腺X射线摄片。16例乳腺癌患者,15例FDGSPECT分期与临床手术分期一致。利用SPECT/CT仪所配备的定位CT,15例乳腺癌患者的病灶可准确定位。结论SPECT/CT符合线路18F-FDG显像在乳腺癌的诊断、转移灶定位以及临床分期方面具有重要的临床应用价值。     

Cervical lymph node metastasis: assessment of radiologic criteria

To estimate the accuracy of different radiologic criteria used to detect cervical lymph node metastasis in patients with head and neck carcinoma, seven different characteristics of 2,719 lymph nodes in 71 neck dissection specimens from 55 patients were assessed. Three lymph node diameters, their location, their number, the presence of a tumor, and the amount of necrosis and fatty metaplasia were recorded. The minimal diameter in the axial plane was found to be the most accurate size criterion for predicting lymph node metastasis. A minimal axial diameter of 10 mm was determined to be the most effective size criterion. The size criterion for lymph nodes in the subdigastric region was 1 mm larger (11 mm). Groups of three or more borderline nodes were proved to increase the sensitivity but did not significantly decrease the specificity. Radiologically detectable necrosis (3 mm or larger) was found only in tumorous nodes and was present in 74% of the positive neck dissection specimens. Shape was not a valuable criterion for the radiologic assessment of the cervical lymph node status.     

CT在术前评估卵巢恶性肿瘤淋巴结转移中的价值

目的探讨全腹CT在卵巢恶性肿瘤淋巴结转移术前评估中的价值。方法对136例原发性卵巢恶性肿瘤患者术前行全腹CT检查,并对淋巴结进行评估,根据部位将淋巴结转移分为腹腔及盆腔淋巴结转移。术后淋巴结组织病理学结果作为诊断淋巴结转移的金标准。结果术前CT诊断卵巢恶性肿瘤患者盆腹腔淋巴结转移的敏感度为47.2%,特异性为67.5%,PPV为48.08%,NPV为66.7%。CT预测盆腔淋巴结转移的敏感度为36.4%、特异性为76.7%、PPV为43.2%、NPV为71.3%。CT预测腹主动脉旁淋巴结转移的敏感度为34.6%,特异性为75.8%,PPV为52.9%,NPV为59.5%。而进一步亚组分析的敏感度等指标并没有明显提高。结论应用腹部CT检查评价卵巢恶性肿瘤是否存在淋巴结转移的准确性有限,但对肿大淋巴结定位、与周围毗邻关系有参考价值。     

Preoperative staging of thyroid papillary carcinoma with ultrasonography

Objective: To evaluate the usefulness of ultrasonography including Doppler flow imaging for the preoperative staging of thyroid papillary carcinoma. Materials and Methods: In 77 patients with thyroid papillary carcinoma who underwent total thyroidectomy, the accuracy of ultrasonography in preoperative clinical staging was assessed with use of pathologic examination on the basis of TNM classification by the International Union Against Cancer (UICC). Results: In 63 (81.8%) cases, T categories were estimated accurately. The sensitivity in depicting tumor extension into the prethyroidal muscle and/or the sternocleidomastoid muscle was 77.8%, whereas the sensitivity for invasion into the trachea and the esophagus was 42.9 and 28.6%, respectively. In 37 (48.1%) cases, N categories were underestimated, and the sensitivity in the detection of regional lymph node metastasis was 36.7%. Doppler flow imaging was performed in 36 patients, and no correlation was found between flow patterns and the presence of local invasion or regional lymph node metastasis. Conclusion: Ultrasonography was useful for preoperative investigation of thyroid papillary carcinoma, but several limitations existed, especially in evaluating extracapsular invasion to deep locations and regional lymph node metastasis.     

食管鳞癌淋巴结转移与CT灌注参数及血管生成的关系

目的:探讨食管鳞癌淋巴结转移与其CT灌注参数及血管生成的关系。方法:50例食管癌患者行MSCT灌注扫描,采用免疫组织化学SP法检测术后标本中MVD及VEGF的表达。分析食管癌淋巴结转移与CT灌注参数中血容量(BV)、血流量(BF)、平均通过时间(MTT)、表面通透性(PS)及MVD、VEGF表达之间的关系。结果:食管鳞癌CT灌注参数中BF、BV、MTT值在有和无淋巴结转移组中分别为(128.81±50.05)和(105.55±43.18))ml/(100g.min)、(7.64±3.11)和(6.33±1.71)ml/100g、(5.62±1.97)和(7.16±3.32)s,差异均无统计学意义(P>0.05),而PS值在有和无淋巴结转移组分别为(18.32±5.39)和(9.66±2.46)ml/(100g.min),差异有高度统计学意义(P<0.01);以PS值>10ml/(100g.min)为阈值预测淋巴结转移的敏感度、特异度、阳性及阴性似然比分别为95.8%、65.4%、2.77和0.06;VEGF及MVD值与食管鳞癌淋巴结转移有显著正相关关系(r值分别为0.752和0.384,P<0.01)。结论:CT灌注成像有助于食管鳞癌淋巴结转移的术前诊断,其中PS值是最有价值的诊断指标。     

贲门癌的CT诊断(附50例分析)

目的　探讨贲门癌CT诊断价值。方法　分析 50例经病理证实的贲门癌的CT表现,全部均行螺旋CT检查。结果　贲门区胃壁增厚 50例,软组织肿块 25例,邻近组织浸润 18例,淋巴结转移 33例。结论　CT可显示贲门癌的大小、形态、邻近组织的浸润和淋巴结的转移,对疾病的评估和治疗方案的选择具有重要的价值。     

乳腺癌动态增强MRI表现与腋窝淋巴结转移及ER、PR的关系

目的探讨乳腺癌MRI表现与腋窝淋巴结转移及雌激素受体(estrogen receptor,ER)、孕激素受体(progesterone receptor,PR)的关系。方法选取我院乳腺癌患者83例,根据患者有无腋窝淋巴结转移、病理类型、ER、PR表达情况进行分组,分析增强MRI表现与其之间的关系。结果有腋窝淋巴结转移者与无腋窝淋巴结转移者增强MRI表现中边缘特征、早期强化模式差异有统计学意义(P<0.05)。83例乳腺癌患者其病理类型分别为浸润性导管癌55例、浸润性小叶癌8例、黏液癌20例;三种病理类型根据分析结果显示:其在边缘特征、早期强化模式、延迟期时间-信号强度曲线类型等增强MRI表现差异有统计学意义(P<0.05)。ER阳性、阴性者根据其增强MRI表现,在边缘特征、内部强化方式之间差异有统计学意义(P<0.05);PR阳性、阴性者其增强MRI表现在边缘特征、早期强化模式之间差异有统计学意义(P<0.05)。结论有腋窝淋巴结转移的患者与增强MRI表现边缘特征、早期强化模式有关;病理类型与边缘特征与强化模式有关;ER阳性与边缘特征与内部强化方式有关、PR阳性与边缘特征、早期强化模式有关。