综合干预措施对初治肺结核患者疗效的影响

目的:探讨综合干预的方法对肺结核患者服药依从性和治疗效果的影响.方法:168位初治肺结核患者随机分为两组,干预组采取综合干预措施,对照组采用门诊拿药后自行服药模式,分析两组患者的服药依从性和治疗效果.结果:干预组患者治愈率为75％,高于对照组45.2％,干预组规范服药率为89.3％,高于对照组53.6％,干预组治疗2个月的涂阳患者痰菌转阴率为66.7％,高于对照组54.2％(P＜0.05).结论:综合干预措施能改善患者规范服药治疗的依从性,提高治疗效果.     

影响复治涂阳肺结核患者疗效的因素分析及护理干预

目的:探讨影响复治涂阳肺结核患者疗效的因素,并进行针对性护理干预,提高治疗依从性和疗效。方法:选择我院内科收治复制涂阳肺结核患者,进行问卷调查,回收问卷进行分析,找出影响患者疗效的因素并进行针对性护理干预措施。分别于干预后1个月、3个月、6个月进行随访和疗效评价。结果:大多数患者治疗依从性提高,疗效满意。结论:对复治涂阳肺结核患者进行针对性护理干预可有效提高患者疗效和生活质量。     

阜新地区初治涂阳肺结核患者的健康行为量表评分调查

目的:调查辽宁阜新地区初治涂阳肺结核患者的健康行为.方法:辽宁阜新地区79例初治涂阳肺结核患者开始治疗前接受"肺结核病人健康行为量表"评估,并与72例同期住院的复治涂阳肺结核患者(对照组)测试结果比较.结果:初治涂阳肺结核患者的的躯体症状、心理焦虑、防结核认知和社会支持等因子得分和健康行为总分均明显高于对照组(P均<0.05～0.01).结论:阜新地区初治涂阳肺结核患者的健康行为评分较差.     

护理干预方法和程度不同对肺结核患者服药依从性的影响

目的:研究和分析护理干预方法和程度不同对肺结核患者服药依从性的影响.方法:对该院诊治的540例肺结核患者的临床病例资料进行回顾性的分析,分为观察组与对照组进行对比,两组中各有270例.对照组患者采用普通护理方式干预,观察组实施针对性护理措施,对两组患者接受护理之后的用药依从性进行对比分析.结果:护理之后的观察组患者的服药依从性显著优于对照组患者(P＜0.05).结论:针对肺结核患者实施针对性的护理干预,能够有效的提高患者的服药依从性,提高治疗效果,促进患者病情恢复.     

影响肺结核患者规则服药依从性的因素及护理对策探讨

目的 了解影响肺结核患者治疗依从性因素及患者服药依从情况,提出相应的护理干预措施.方法 对门诊患者采用问卷方式,了解患者服药规律情况及相关因素.结果 结核患者规律服药者为46.67%,影响患者规律服药的因素主要与患者年龄、学历、收入、对结核病的知晓情况等因素有关.结论 加强对结核患者的抗结核治疗宣教、督导、随访,促进其应用抗结核药物的依从性,利于结核病的防治.     

285例回汉族肺结核病人近远期疗效分析

目的 对贫困地区回汉族肺结核病忠者近远期疗效进行分析。方法按照世界银行贷款中国结核控制项目工作手册要求．采用统一诊断标准、治疗方案、药品、服药时间、统一管理方法．对285例回汉族忡结核新发涂阳病人进行治疗。结果回汉族新发涂阳肺结核病人痰菌阴转率分别显95．65％和98．96％（X^2=3．31,P〉0.05）：回族新发涂阳肺结核病人3年远期复发率略高于汉族．但统计学无差异（X^2=0．27,P〉0．05）。结论贫困地区回汉族新发涂阳肺结核病人近远期疗效无显著性差异。     

120例免费治疗肺结核病人的家庭护理

肺结核患者采取家庭护理的目的:并且能方便病人,因为肺结核病人大多数是农村贫困的农民,经济条件很差,同时在家属及亲人的呵护下,使病人保持良好的心态,增加饮食,保持足够的睡眠,对疾病的恢复更有利.方法 对120例肺结核患者家庭护理进行回顾性的分析,初治涂阳、涂阴肺结核病人使用2H3R3Z3E3/4H3R3;复治涂阳病人使用4HRZES/6H3R3E3方案.结果 在实施家庭护理干预后,遵医行为、自护能力、健康行为的建立等方面有明显的提高和改善,而且肺结核患者或家属缺乏正确的认知.结论 实施家庭护理干预可以有效地改善肺结核患者治疗的依从性,使患者能充分与医生配合,在自服药的情况下,能保证早期、联合、适量、规律、全程的完成治疗,减少耐药肺结核患者的产生,促进患者的最终康复.     

护理干预对初治涂阳肺结核患者疗效的影响

目的：分析护理干预对初治涂阳肺结核患者治疗依从性及疗效的影响。方法：160例初治涂阳肺结核患者随机分为干预组和对照组。在抗结核治疗强化期,干预组采取针对性健康宣教,同时对患者的不良情绪采取积极的心理干预。而对照组则采取常规健康教育。观察两组患者在抗结核治疗强化期的疗效及治疗过程中的依从情况。结果：干预组服药依从率达96.25%,明显高于对照组的86.25%（P〈0.05）;强化治疗期末痰菌阴转率干预组96.2%明显优于对照组的83.80%（P〈0.05）;强化治疗期末肺部病灶吸收情况,干预组有效率93.75%明显高于对照组的82.50%。结论：针对性健康教育辅以心理干预,能够明显改善初治涂阳肺结核患者的治疗依从性,进而提高治疗效果。     

护理指导对肺结核患者治疗服药依从性的影响

目的:探讨护理指导措施对肺结核患者治疗服药依从性的影响效果.方法:选择房县疾病预防控制中心结防门诊部2010~2012年间治的78例涂阳肺结核患者,将其随机分为指导组和对照组,每组各39例,对照组给予常规护理,指导组在此基础上给予心理护理、健康教育、药物指导、生活指导等综合护理指导,观察比较两组患者的治疗效果.结果:护理指导组患者服药依从率为89.7%,高于对照组的48.7%.结论:通过对肺结核患者进行心理护理、健康教育、药物、生活等综合护理指导,能有效提高患者的治疗服药依从性,改善其认知及行为,有助于提高患者的生活质量和治疗效果.     

综合护理干预措施对肺结核患者服药依从性的影响

目的 分析综合护理干预措施对肺结核患者药物治疗依从性的影响.方法 选取我院2019年1月～2019年12月期间收治的120例肺结核患者,所有患者均给予抗结核药物治疗,对照组给予常规护理,观察组给予综合护理干预措施,观察两组患者实施护理前后服药依从性情况和两组临床治疗效果.结果 观察组患者服药依从性、治疗总有效率均明显高于对照组,两组对比差异具有统计学意义(P<0.05).结论 对肺结核患者实施综合护理干预措施,可有效提高患者的服药依从性,也因此改善了治疗效果,值得进行进一步研究.     

Value of D-Dimers in patients with acute aortic dissection

Objective: To evaluatel the value of D-dimers in patients with acute aortic dissection (AAD). Methods: This study consisted of 16 patients with AAD and 27 non-AAD patients. Serum D-dimets were measured by Sta-Liatest D-DI immunoturbidimetric assay. Results: D-dimer level was higher (P ＜ 0.001) in patients with AAD(7.91 ± 5.52 μg/ml) than that in non- AAD group(1.57±1.24 μg/ml). D-dimer was positive (＞0.4 μg/ml) in all patients with AAD and in 10 control group patients (37%). Among patients with acute AAD, D-dimers tended to be higher in Stanford A than in Stanford B (8.67 ± 4.31 μg/ml vs. 3.24±1.27 μg/ml, P ＜0.01). D-dimer values tended to be higher in more extended disease(3.84 ± 1.65 μg/ml, 8.57 ± 3.58 μg/ml and 11.87 ± 5.69 μg/ml in thoracic aorta, thoracic and abdominal aorta, thoracic and abdominal aorta and iliacal arteries, respectively, P ＜ 0.05 for both 8.57 ± 3.58 and 11.87 ± 5.69 vs. 3.84 ± 1.65 ). Including the control group into the analysis, we found a sensitivity of 100%, a negative predictive value of 100%, and a specificity of 66% and a positive predictive value of 64% for D-dimer in diagnosis of AAD in our patients with suspected AAD. Conclusion: D-dimer was elevated in patients with AAD. A negative D-dimer test result could be useful in excluding AAD.     

Research of combined liver-kidney transplantation model in rats

Objective： To set up a simple and reliable rat model of combined liver-kidney transplantation. Methods： SD rats served as both donors and recipients. 4℃ sodium lactate Ringer＇s was infused from portal veins to donated livers,and from abdominal aorta to donated kidneys, respectively. Anastomosis of the portal vein and the inferior vena cava （IVC） inferior to the right kidney between the graft and the recipient was performed by a double cuff method, then the superior hepatic vena cava with suture. A patch of donated renal artery was anastomosed to the recipient abdominal aorta. The urethra and bile duct were reconstructed with a simple inside bracket. Results： Among 65 cases of combined liver-kidney transplantation, the success rate in the late 40 cases was 77.5%. The function of the grafted liver and kidney remained normal. Conclusion： This rat model of combined liver-kidney transplantation can be established in common laboratory conditions with high success rate and meet the needs of renal transplantation experiment.     

APPLICATION OF LORNOXICAM TO PATIENT-CONTROLLED ANALGESIA IN PATIENTS UNDERGOING ABDOMINAL SURGERIES

FOR anesthesiologis s ,treatingpostoperativepainhas alwaysbeen a problem.Althoughopioidshave been provedtobe effective,theirsideeffectscouldnotbeignored.With thedevelopmentofscienceand pharmacology,many drugs with aspectsof satisfactoryanalgesicefficacyand couldbe welltoleratedby patientshave been developed.And lornoxicamisone of them, which isa non-steroidalanti-inflammatorydrug (NSAID ), with analgesic, anti-infl-ammatory,andantipyreticproperties.Itseliminationhalf-time(3 to 5 hours) isle…     

安心颗粒对急诊经皮冠状动脉介入术后生活质量影响的研究

目的：评价使用安心颗粒对急诊经皮冠状动脉介入术（PPCI）术后生活质量的影响.方法：将160例接受PPCI的急性ST段抬高型心肌梗死患者随机分为安心颗粒组（术前顿服安心颗粒8.8g,术后安心颗粒4.4 g/次,每日2次）和对照组（仅接受基础药物治疗）.所有患者均服用阿司匹林、氯吡格雷和阿托伐他汀.分别在入院时、出院前1d、出院后180 d时,应用心肌梗死多维度量表（MIDAS）、中文版SF-36评价量表对患者生活质量评分.并观察术后30 d以内的出血并发症、血小板减少症发生情况.结果：入院时和出院前1d,两组患者的心肌梗死MIDAS、SF-36量表评分比较无差异（P＞0.05）;出院后180 d时,与对照组比较,安心颗粒组MIDAS、SF-36评分明显减低（P＜0.05）;组内与入院时比较,两组出院前1d、出院后180 d时,MIDAS、SF-36评分均降低（P＜0.05）.两组患者在随访期间均无大量出血、少量出血、重度和极重度血小板减少症发生,安心颗粒组有4例、对照组有7例发生不明显出血（P＞0.05）.两组发生轻度血小板减少症的患者数比较无差异（P＞0.05）.结论：PPCI使用安心颗粒,能改善急性ST段抬高型心肌梗死患者的生活质量,且不增加出血风险.     

The comparative studies of the influences of Urapidil and Nicardipine on sino-atrial node function, atrio-ventricular node function and hemodynamics

Objective:To investigate the influences of urapidil and nicardipine on rabbit sinus function,atrio-ventricular node function and hemodynamics.Methods:Thirty-two Angora's rabbits were selected and randomly divided into four groups.U1 group:urapidil 0.25 mg/kg;U2 group:urapidil 0.5 mg/kg;N1 group:nicardipine 10 μg/kg;N2 group:nicardipine 20 μg/kg.All these medicine were administrated within 30 seconds.Measurements were taken before and after the administration of urapidil or nicardipine for the following data:mean blood pressure(MAP),heart rate(HR),sino-atrial conduction time(SACT),maximal sinoatrial recovery time(SNRTmax)corrected sinus node recovery time(CSNRT),index of sinus node recovery time(SNRTI),Wenckebach A-V conduction frequency (WB),and P-R interval.Results:Significant MAP and HR changes were identified in all of the four groups before and after administration of both urapidil and nicardipine.No significant changes could be found in the rest of the parameters.Intergroup analysis showed that SACT and CSNRT of N1 and N2 groups were shorter than those of the U2 group(P＜0.01);the MAP decreased(P＜0.01)and the HR increased drastically(P＜0.01).Conclusions:Neither urapidil(0.25 mg/kg,0.5 mg/kg)nor nicardipine(10μg/kg,20μg/kg)has any significant influence on rabbit sinus function or rabbit atrio-ventricular node function.Nicardipine could be a better choice than urapidil for parafunctional sinus node patients.     

Expression of OPGmRNA and ODFmRNA in the patients of hip fracture due to osteoporosis

Objective：To investigate the gene expression of osteoprotegerin（OPG） and osteoclast differentiation factor（ODF） in the bone tissue of patients with hip fracture due to osteoporosis. Methods：OPGmRNA and ODFmRNA in the bone tissue in 50 cases of osteoporosis sufferers（over 50 years old） with hip fracture（Observer Group） and 30 cases of hip facture sufferers with no osteoporosis（Control group） were analyzed with the Semi-Quantitative RT-PCR method. Results：The mRNA expressed of ODF, OPG were both high in the patients with hip fracture. In the control group, the expression of OPG mRNA was observed, while the expression of ODF mRNA was very slight. Conclusion：Aged patients contained all signals including OPG, ODF that are essential for inducing osteoclastogenesis and promoting bone resorption.     

The clinicopathological and immuohistochemical analysis of solid-pseudopapillary tumor of the pancreas： report of 9 cases

Objective：To investigate the clinical features, pathological characteristics and immunophenotype of solid-pseudopapillary tumor of the pancreas（SPTP）. Methods：Nine surgically treated cases of SPTP were retrospectively reviewed. Hematoxylin and Eosin（HE） staining and immunohistochemical staining were used to analyze all cases, and the general clinical data was collected. Results：Six patients were asymptomatic except for a palpable mass. Two patients complained of vague-epigastric pain. One patient appeared jaundice. The tumor was encapsulated and solid tissues alternately with cystic tissues. Histologically, the histological structure of solid portion was pseudopapillary with a fibrovascular core. Tumor cells were uniform and medium-sized which were arranged in sheets ets or nests or pseudopapillary patterns. Immunohistochemical studies demonstrated that SPTP proved positive in vimentin（9/9 cases）, AAT（9/9 cases）, NSE（9/9 cases）, ACT（7/9 cases）, CK20（2/9 cases）, CgA（1/9 cases）, S-100（3/gcases）, PR（4/gcases）, Syn（3/9 cases） and CD56（5/9cases）, negative in CEA and ER. Conclusion：SPTP is a tumor predominantly occurring in young women frequently without special symptoms. This tumor has various characteristical histological patterns with different immunophenotype.     

Acupuncture Combined with Spinal Tui Na for Treatment of Primary Dysmenorrhea in 30 Cases

Objective: To observe the therapeutic effects in acupunture treatment of primary dysmenorrhea combined with spinal Tui Na, and study its mechanism. Methods: Thirty cases of the treatment group were treated by acupuncture combined with spinal Tui Na, and thirty cases in the control group were treated by routine acupuncture. Results: The total effective rate was 93.3% in the treatment group, and 73.3% in the control group, with a significant difference between the two groups (P<0.05). Conclusions: Acupuncture combined with spinal Tui Na has good prospects for treatment of primary dysmenorrhea.     

Luo Lingjie's Experience in Treating Chronic Nephropathy

In treating chronic nephropathy,Luo Lingjie,a chief physician,pays attention to regulating the balance between yin and yang,treating infection if present,and removing pathogenic factors.He prescribes gentle drugs and uses carefully strongly warming-tonifying ones,emphasizes the importance of persuading the patient to persist in treatment with medication and nurse one's health for recuperation,and is good at combined use of TCM and western medicine therapy and brings the merits of various therapies into full play,with obvious theraoeutic effects.     

Dr.Zhang Ren's Experience in the Acupuncture Treatment of Different Diseases with the Same Therapeutic Principle

Dr.Zhang Ren,the chief physician,is the chairman of Shanghai Acupuncture and Moxibustion Association.Having been engaged in medicine for about 40 years,he is experienced in treating various intractable diseases.In his long years of clinical practice,he advocates taking the TCM differentiation as the basis to seek for the acupuncture method for treatment of modern intractable diseases.The author of this essay had the fortune to follow Dr.Zhang in study.The following is a summary of Dr.Zhang's experience in the acupuncture treatment for different intractable diseases with the same therapeutic principle.