CT引导下经皮穿刺活检术对肺内孤立性结节的临床意义

目的:探讨CT引导下经皮肺穿刺活检术对肺内孤立性结节的临床意义。方法:分析40例肺内孤立性结节行CT引导下经皮肺穿刺活检并经手术病理证实的资料。结果:40例肺内孤立性结节病灶经手术病理证实,穿刺成功率100%,活检诊断准确率97.5%(39/40)。并发气胸1例,穿刺后咯血痰1例。结论:CT引导下经皮肺穿刺活检术是安全的,对肺内孤立性结节的明确诊断具有较高的临床意义。     

CT引导下行孤立性肺结节穿刺活检的临床运用

目的:探讨孤立性肺结节在CT引导下穿刺活检术的临床运用价值.方法:对32例孤立性肺结节患者在CT引导下进行皮肺穿刺活检术,将所有的活检组织进行病理检查,并将所有病理资科与影像学诊断资料作对比分析.结果:32例孤立性肺结节穿刺成功率达100％,经病理学检查证实肺癌共23例,炎性假瘤5例,结核3例,1例取得坏死组织无法定性;在对孤立肺结节的定性诊断方面,穿刺活检的病理学诊断明显优于影像学诊断.结论.CT引导下经皮肺穿刺活检术是一种微创、安全的检查方法,它对孤立性肺结节病灶定性诊断率较高,临床应用价值较大.     

CT引导下孤立性肺结节病灶穿刺活检的临床应用

为探讨其CT引导下经皮肺穿刺活检的临床应用价值,回顾性分析螺旋CT引导下经皮肺穿刺活检的52例该类病灶.CT引导下肺内孤立性肺结节(SPN)穿刺活检术,微创、安全、有效,对于定性诊断有非常大的帮助.     

多层螺旋CT导引下孤立性肺结节穿刺活检分析

目的 探讨多层螺旋CT(MSCT)导引下半自动活检针经皮肺穿刺活检对孤立性肺小结节的诊断价值.方法 选取50例孤立性肺结节患者,均行CT导引下经皮肺穿刺活检,对所取组织行组织病理学检查.以术后病理及临床和影像结果为最终诊断,计算经皮肺穿刺活检的阳性率、成功率以及并发症发生率.结果 MSCT导引下肺穿刺活检病理检查结果阳性率为96%(48/50),穿刺成功率为98%(49/50).并发症:气胸11例(22%),出血13例(26%),气胸合并出血5例(10%),咯血1例(2%),均较轻微,无严重并发症.结论 MSCT导引下半自动活检针经皮肺穿刺活检是一种安全、快捷、准确的诊断孤立性肺结节的方法.     

CT引导下经皮肺穿刺活检72例临床分析

目的:探讨CT引导下经皮肺穿刺活检术对肺内周围性孤立性结节及弥漫性病变的临床价值.方法:收集2009年7月至2010年7月72例肺内周围性孤立性结节及弥漫性病变患者,行CT引导下经皮肺穿刺活检术,获取病理结果后行相关临床治疗或随访观察.结果:64例肺内周围性孤立性结节病灶在CT引导下经皮肺穿刺活检诊断为肺癌50例、结核...     

74例孤立性肺结节临床诊治分析

[目的]分析74例孤立性肺结节临床特征及诊断。[方法]对74例孤立性肺结节患者临床、CT、经皮穿刺肺活检术及手术病理进行回顾性分析。[结果]74例患者CEA增高51例（69％），痰脱落细胞学发现癌细胞9例（12％），CT诊断肺癌56例。26例行经皮穿刺肺活检术，42例手术治疗，术后诊断肺癌46例（62％）。本组病例确诊肺癌与非肺癌分组比较，CEA、HRCT与经皮穿刺肺活检术阳性和诊断分别为38（74．51％）、13（25．49％）、39（75．00％）、13（25．00％）、21（80．77％）、5（19．23％），两组间比较有显著性统计学差异。[结论]孤立性肺结节患者以周围型肺癌及结核球居多，诊断以CEA、薄层CT扫描、经皮穿刺肺活检术为主要手段。     

CT引导经皮肺穿刺活检的临床体会

目的 研究应用CT引导经皮肺穿刺活检术在临床中的意义。方法 选取64例行CT引导经皮肺穿刺活检，回顾性总结CT引导经皮肺穿刺活检的诊断价值及并发症。结果 64例行CT经皮肺穿刺活检患者中诊断率96．8％，并发症咯血65．6％，气胸3．1％。结论 CT引导经皮肺穿刺活检具有重要的临床价值，并且安全可行。     

负压垫固定CT引导下经皮肺穿刺活检术的诊断价值

目的 探讨负压垫固定CT引导下经皮肺穿刺活检对肺部占位性病变的诊断价值.方法 收集谈院呼吸内科2013年11月至2014年12月接受激光定位配合负压垫固定CT引导下经皮肺穿刺活检术的288例患者,分析负压垫固定CT引导下经皮肺穿刺活检术对肺恶性肿瘤的诊断阳性率.结果 288例经皮肺穿刺的病理结果为恶性肿瘤153例,良性病变110例,未确诊25例,敏感度、特异度及准确率分别为86.9％、100.0％及92.0％;穿刺并发症包括气胸(17.0％),咯血(9.7％),咯血合并气胸(o.3％).结论 负压垫固定CT引导下经皮肺穿刺活检是一种安全、准确、微创的诊断方法,值得推广.     

肺内周围性孤立性结节的CT引导下经皮肺穿刺活检的临床价值

目的:探讨CT引导下经皮肺穿刺活检术对肺内周围性孤立性结节的临床价值。方法:收集2004年3月至2005年3月期间50例肺内周围性孤立性结节行CT引导下经皮肺穿刺活检并经手术病理、临床治疗或随访观察证实的资料。采用美国Cook公司的抽吸式活检针和套管式自动活检枪,选择最佳穿刺层面及穿刺点获取标本。结果:50例肺内周围性孤立性结节病灶中经手术病理、临床治疗或随访观察证实为肺癌38例(腺癌23例、鳞癌12例、小细胞癌3例)、结核球8例,炎性假瘤4例。而CT引导下经皮肺穿刺活检诊断为肺癌36例(腺癌21例、鳞癌12例、小细胞癌3例)、结板球8例,炎性假瘤6例。并发症有气胸5例(10.0%)、咯血3例(6.0%)、痰中带血2例(4.0%)。结论:CT引导下经皮肺穿刺活检为肺内周围性孤立性结节的明确诊断提供一种安全有效的检查方法,具有较高的临床应用价值。     

27例肺结节及肿块样变CT引导下经皮肺穿刺活检分析

目的:回顾分析27例肺部结节及肿块病变在CT引导下经皮肺穿刺活检病例,探讨CT引导下经皮肺穿刺活检对肺部占位病变的诊断价值及安全适应性.方法:对27例肺部肿块在CT引导下经皮肺穿刺获取材料后送病理检查.结果:27例全部穿刺成功,活检诊断准确26例.27例中8例发生气胸.结论:CT引导下经皮肺穿刺活检术简便易行,安全有效...     

Value of D-Dimers in patients with acute aortic dissection

Objective: To evaluatel the value of D-dimers in patients with acute aortic dissection (AAD). Methods: This study consisted of 16 patients with AAD and 27 non-AAD patients. Serum D-dimets were measured by Sta-Liatest D-DI immunoturbidimetric assay. Results: D-dimer level was higher (P ＜ 0.001) in patients with AAD(7.91 ± 5.52 μg/ml) than that in non- AAD group(1.57±1.24 μg/ml). D-dimer was positive (＞0.4 μg/ml) in all patients with AAD and in 10 control group patients (37%). Among patients with acute AAD, D-dimers tended to be higher in Stanford A than in Stanford B (8.67 ± 4.31 μg/ml vs. 3.24±1.27 μg/ml, P ＜0.01). D-dimer values tended to be higher in more extended disease(3.84 ± 1.65 μg/ml, 8.57 ± 3.58 μg/ml and 11.87 ± 5.69 μg/ml in thoracic aorta, thoracic and abdominal aorta, thoracic and abdominal aorta and iliacal arteries, respectively, P ＜ 0.05 for both 8.57 ± 3.58 and 11.87 ± 5.69 vs. 3.84 ± 1.65 ). Including the control group into the analysis, we found a sensitivity of 100%, a negative predictive value of 100%, and a specificity of 66% and a positive predictive value of 64% for D-dimer in diagnosis of AAD in our patients with suspected AAD. Conclusion: D-dimer was elevated in patients with AAD. A negative D-dimer test result could be useful in excluding AAD.     

Research of combined liver-kidney transplantation model in rats

Objective： To set up a simple and reliable rat model of combined liver-kidney transplantation. Methods： SD rats served as both donors and recipients. 4℃ sodium lactate Ringer＇s was infused from portal veins to donated livers,and from abdominal aorta to donated kidneys, respectively. Anastomosis of the portal vein and the inferior vena cava （IVC） inferior to the right kidney between the graft and the recipient was performed by a double cuff method, then the superior hepatic vena cava with suture. A patch of donated renal artery was anastomosed to the recipient abdominal aorta. The urethra and bile duct were reconstructed with a simple inside bracket. Results： Among 65 cases of combined liver-kidney transplantation, the success rate in the late 40 cases was 77.5%. The function of the grafted liver and kidney remained normal. Conclusion： This rat model of combined liver-kidney transplantation can be established in common laboratory conditions with high success rate and meet the needs of renal transplantation experiment.     

APPLICATION OF LORNOXICAM TO PATIENT-CONTROLLED ANALGESIA IN PATIENTS UNDERGOING ABDOMINAL SURGERIES

FOR anesthesiologis s ,treatingpostoperativepainhas alwaysbeen a problem.Althoughopioidshave been provedtobe effective,theirsideeffectscouldnotbeignored.With thedevelopmentofscienceand pharmacology,many drugs with aspectsof satisfactoryanalgesicefficacyand couldbe welltoleratedby patientshave been developed.And lornoxicamisone of them, which isa non-steroidalanti-inflammatorydrug (NSAID ), with analgesic, anti-infl-ammatory,andantipyreticproperties.Itseliminationhalf-time(3 to 5 hours) isle…     

安心颗粒对急诊经皮冠状动脉介入术后生活质量影响的研究

目的：评价使用安心颗粒对急诊经皮冠状动脉介入术（PPCI）术后生活质量的影响.方法：将160例接受PPCI的急性ST段抬高型心肌梗死患者随机分为安心颗粒组（术前顿服安心颗粒8.8g,术后安心颗粒4.4 g/次,每日2次）和对照组（仅接受基础药物治疗）.所有患者均服用阿司匹林、氯吡格雷和阿托伐他汀.分别在入院时、出院前1d、出院后180 d时,应用心肌梗死多维度量表（MIDAS）、中文版SF-36评价量表对患者生活质量评分.并观察术后30 d以内的出血并发症、血小板减少症发生情况.结果：入院时和出院前1d,两组患者的心肌梗死MIDAS、SF-36量表评分比较无差异（P＞0.05）;出院后180 d时,与对照组比较,安心颗粒组MIDAS、SF-36评分明显减低（P＜0.05）;组内与入院时比较,两组出院前1d、出院后180 d时,MIDAS、SF-36评分均降低（P＜0.05）.两组患者在随访期间均无大量出血、少量出血、重度和极重度血小板减少症发生,安心颗粒组有4例、对照组有7例发生不明显出血（P＞0.05）.两组发生轻度血小板减少症的患者数比较无差异（P＞0.05）.结论：PPCI使用安心颗粒,能改善急性ST段抬高型心肌梗死患者的生活质量,且不增加出血风险.     

The comparative studies of the influences of Urapidil and Nicardipine on sino-atrial node function, atrio-ventricular node function and hemodynamics

Objective:To investigate the influences of urapidil and nicardipine on rabbit sinus function,atrio-ventricular node function and hemodynamics.Methods:Thirty-two Angora's rabbits were selected and randomly divided into four groups.U1 group:urapidil 0.25 mg/kg;U2 group:urapidil 0.5 mg/kg;N1 group:nicardipine 10 μg/kg;N2 group:nicardipine 20 μg/kg.All these medicine were administrated within 30 seconds.Measurements were taken before and after the administration of urapidil or nicardipine for the following data:mean blood pressure(MAP),heart rate(HR),sino-atrial conduction time(SACT),maximal sinoatrial recovery time(SNRTmax)corrected sinus node recovery time(CSNRT),index of sinus node recovery time(SNRTI),Wenckebach A-V conduction frequency (WB),and P-R interval.Results:Significant MAP and HR changes were identified in all of the four groups before and after administration of both urapidil and nicardipine.No significant changes could be found in the rest of the parameters.Intergroup analysis showed that SACT and CSNRT of N1 and N2 groups were shorter than those of the U2 group(P＜0.01);the MAP decreased(P＜0.01)and the HR increased drastically(P＜0.01).Conclusions:Neither urapidil(0.25 mg/kg,0.5 mg/kg)nor nicardipine(10μg/kg,20μg/kg)has any significant influence on rabbit sinus function or rabbit atrio-ventricular node function.Nicardipine could be a better choice than urapidil for parafunctional sinus node patients.     

Expression of OPGmRNA and ODFmRNA in the patients of hip fracture due to osteoporosis

Objective：To investigate the gene expression of osteoprotegerin（OPG） and osteoclast differentiation factor（ODF） in the bone tissue of patients with hip fracture due to osteoporosis. Methods：OPGmRNA and ODFmRNA in the bone tissue in 50 cases of osteoporosis sufferers（over 50 years old） with hip fracture（Observer Group） and 30 cases of hip facture sufferers with no osteoporosis（Control group） were analyzed with the Semi-Quantitative RT-PCR method. Results：The mRNA expressed of ODF, OPG were both high in the patients with hip fracture. In the control group, the expression of OPG mRNA was observed, while the expression of ODF mRNA was very slight. Conclusion：Aged patients contained all signals including OPG, ODF that are essential for inducing osteoclastogenesis and promoting bone resorption.     

Acupuncture Combined with Spinal Tui Na for Treatment of Primary Dysmenorrhea in 30 Cases

Objective: To observe the therapeutic effects in acupunture treatment of primary dysmenorrhea combined with spinal Tui Na, and study its mechanism. Methods: Thirty cases of the treatment group were treated by acupuncture combined with spinal Tui Na, and thirty cases in the control group were treated by routine acupuncture. Results: The total effective rate was 93.3% in the treatment group, and 73.3% in the control group, with a significant difference between the two groups (P<0.05). Conclusions: Acupuncture combined with spinal Tui Na has good prospects for treatment of primary dysmenorrhea.     

Luo Lingjie's Experience in Treating Chronic Nephropathy

In treating chronic nephropathy,Luo Lingjie,a chief physician,pays attention to regulating the balance between yin and yang,treating infection if present,and removing pathogenic factors.He prescribes gentle drugs and uses carefully strongly warming-tonifying ones,emphasizes the importance of persuading the patient to persist in treatment with medication and nurse one's health for recuperation,and is good at combined use of TCM and western medicine therapy and brings the merits of various therapies into full play,with obvious theraoeutic effects.     

Dr.Zhang Ren's Experience in the Acupuncture Treatment of Different Diseases with the Same Therapeutic Principle

Dr.Zhang Ren,the chief physician,is the chairman of Shanghai Acupuncture and Moxibustion Association.Having been engaged in medicine for about 40 years,he is experienced in treating various intractable diseases.In his long years of clinical practice,he advocates taking the TCM differentiation as the basis to seek for the acupuncture method for treatment of modern intractable diseases.The author of this essay had the fortune to follow Dr.Zhang in study.The following is a summary of Dr.Zhang's experience in the acupuncture treatment for different intractable diseases with the same therapeutic principle.     

The clinicopathological and immuohistochemical analysis of solid-pseudopapillary tumor of the pancreas： report of 9 cases

Objective：To investigate the clinical features, pathological characteristics and immunophenotype of solid-pseudopapillary tumor of the pancreas（SPTP）. Methods：Nine surgically treated cases of SPTP were retrospectively reviewed. Hematoxylin and Eosin（HE） staining and immunohistochemical staining were used to analyze all cases, and the general clinical data was collected. Results：Six patients were asymptomatic except for a palpable mass. Two patients complained of vague-epigastric pain. One patient appeared jaundice. The tumor was encapsulated and solid tissues alternately with cystic tissues. Histologically, the histological structure of solid portion was pseudopapillary with a fibrovascular core. Tumor cells were uniform and medium-sized which were arranged in sheets ets or nests or pseudopapillary patterns. Immunohistochemical studies demonstrated that SPTP proved positive in vimentin（9/9 cases）, AAT（9/9 cases）, NSE（9/9 cases）, ACT（7/9 cases）, CK20（2/9 cases）, CgA（1/9 cases）, S-100（3/gcases）, PR（4/gcases）, Syn（3/9 cases） and CD56（5/9cases）, negative in CEA and ER. Conclusion：SPTP is a tumor predominantly occurring in young women frequently without special symptoms. This tumor has various characteristical histological patterns with different immunophenotype.