The assessment of the outliers of logistic regression model and its clinical application

ＴｈｅａｓｓｅｓｓｍｅｎｔｏｆｔｈｅｏｕｔｌｉｅｒｓｏｆｌｏｇｉｓｔｉｃｒｅｇｒｅｓｓｉｏｎｍｏｄｅｌａｎｄｉｔｓｃｌｉｎｉｃａｌａｐｐｌｉｃａｔｉｏｎＹｉＤｏｎｇ（易东）；ＸｕＲｕｆｕ（许汝福）；ＺｈａｎｇＷｅｉ（张蔚）；ＹｉｎＱｕａｎｈｕａｎ（尹...     

Effects of Hantaan virus on cytoskeletons of human endothelial cells

ＥｆｆｅｃｔｓｏｆＨａｎｔａａｎｖｉｒｕｓｏｎｃｙｔｏｓｋｅｌｅｔｏｎｓｏｆｈｕｍａｎｅｎｄｏｔｈｅｌｉａｌｃｅｌｌｓＺｈｕｐｉｎｇ（朱平）；ＬｉｕＪｕｎｂｉｎ（刘俊彬）；Ｙａｎｒｏｎｇ（阎荣）；ＫａｎｇＷｅｎｚｈｅｎ（康文臻）；ＷｕＨｏｎｇ（吴红）...     

Histopathological and immunohistochemical studies of 120 cases of osteosarcoma

Ｈｉｓｔｏｐａｔｈｏｌｏｇｉｃａｌａｎｄｉｍｍｕｎｏｈｉｓｔｏｃｈｅｍｉｃａｌｓｔｕｄｉｅｓｏｆ１２０ｃａｓｅｓｏｆｏｓｔｅｏｓａｒｃｏｍａＧａｏＦｅｎｇｘｕｎ（高奉浔）；ＬｉＺｅｎｇｐｅｎｇ（李增鹏）；ＤｏｎｇＺｈｉｑｉａｎ（董志谦）；ＳｕＨｏｎｇ...     

Pancreatic blood perfusion in sodium taurocholate－induced pancreatitis in rats

Ｐａｎｃｒｅａｔｉｃｂｌｏｏｄｐｅｒｆｕｓｉｏｎｉｎｓｏｄｉｕｍｔａｕｒｏｃｈｏｌａｔｅ－ｉｎｄｕｃｅｄｐａｎｃｒｅａｔｉｔｉｓｉｎｒａｔｓＬｉｕＱｕａｎｆａｎｇ（刘全芳）；ＷａｎｇＢｅｎｍａｏ（王本茂）；ＴａｎｇＹａｎ（唐岩）；ＬｉＳｈａｏｈｕａ（...     

A clinical study of penetrating craniocerebral injuries caused by firearms

Ａｃｌｉｎｉｃａｌｓｔｕｄｙｏｆｐｅｎｅｔｒａｔｉｎｇｃｒａｎｉｏｃｅｒｅｂｒａｌｉｎｊｕｒｉｅｓｃａｕｓｅｄｂｙｆｉｒｅａｒｍｓ￥ＺｈａｎｇＸｉａｎｇ（章翔）；ＬｉｕＷｅｉｐｉｎｇ（刘卫平）；ＺｈａｎｇＪｉａｎｎｉｎｇ（张剑宁）；ＷａｎｇＬｉｇｅｎ...     

Screening of controls in cass-control study of infectious diseases

Ｓｃｒｅｅｎｉｎｇｏｆｃｏｎｔｒｏｌｓｉｎｃａｓｓ－ｃｏｎｔｒｏｌｓｔｕｄｙｏｆｉｎｆｅｃｔｉｏｕｓｄｉｓｅａｓｅｓＬｉＬｉａｎｇｓｈｏｕ（李良寿）；ＸｕＤｅｚｈｏｎｇ（徐德忠）；ＹａｎＹｏｎｇｐｉｎｇ（阎永平）（ＤｅｐａｒｔｍｅｎｔｏｆＥｐｉｄｅｍ...     

A study of point mutation of ras genes in human gastric cancer

Ａｓｔｕｄｙｏｆｐｏｉｎｔｍｕｔａｔｉｏｎｏｆｒａｓｇｅｎｅｓｉｎｈｕｍａｎｇａｓｔｒｉｃｃａｎｃｅｒ￥ＷａｎｇＪｕｎｒｕ（王俊茹）；ＬｉｕＷｅｉｗｅｎ（刘为纹）；ＤｅｎｇＧｕｏｒｅｎ（邓国仁）；ＬｕＹｏｕｙｏｎｇ（吕有勇）；ＷａｎｇＸｉｎ（王欣）（...     

Logistic regression analysis of prognostic factors for dilated cardiomyopathy

Ｌｏｇｉｓｔｉｃｒｅｇｒｅｓｓｉｏｎａｎａｌｙｓｉｓｏｆｐｒｏｇｎｏｓｔｉｃｆａｃｔｏｒｓｆｏｒｄｉｌａｔｅｄｃａｒｄｉｏｍｙｏｐａｔｈｙ￥ＬｉＬｏｎｇｇｕｉ（李隆贵）；ＨｕａｎｇＪｉａｎ（黄坚）；ＺｈｕＳｈａｎｊｕｎ（祝善俊）（Ｄｅｐａｒｔｍｅｎｔ...     

Dynamic study of TNF effects on skeletal muscle proteolysis in early stage of severe scalding in rats

ＤｙｎａｍｉｃｓｔｕｄｙｏｆＴＮＦｅｆｆｅｃｔｓｏｎｓｋｅｌｅｔａｌｍｕｓｃｌｅｐｒｏｔｅｏｌｙｓｉｓｉｎｅａｒｌｙｓｔａｇｅｏｆｓｅｖｅｒｅｓｃａｌｄｉｎｇｉｎｒａｔｓ￥ＬｉＬｉｎ（李林）；ＤｏｎｇＹａｎｌｉｎ（董燕麟）；ＹａｎｇＣｈｕｎ（杨春）；...     

Inhibitory effect of matrine on tumor necrosis factor production and protein kinase C activity

ＩｎｈｉｂｉｔｏｒｙｅｆｆｅｃｔｏｆｍａｔｒｉｎｅｏｎｔｕｍｏｒｎｅｃｒｏｓｉｓｆａｃｔｏｒｐｒｏｄｕｃｔｉｏｎａｎｄｐｒｏｔｅｉｎｋｉｎａｓｅＣａｃｔｉｖｉｔｙＺｈａｎｇＪｕｎｐｉｎｇ（张俊平）；ＨｕＺｈｅｎｌｉｎ（胡振林）；ＬｉｎＷｅｎ（林文）；...     

APPLICATION OF LORNOXICAM TO PATIENT-CONTROLLED ANALGESIA IN PATIENTS UNDERGOING ABDOMINAL SURGERIES

FOR anesthesiologis s ,treatingpostoperativepainhas alwaysbeen a problem.Althoughopioidshave been provedtobe effective,theirsideeffectscouldnotbeignored.With thedevelopmentofscienceand pharmacology,many drugs with aspectsof satisfactoryanalgesicefficacyand couldbe welltoleratedby patientshave been developed.And lornoxicamisone of them, which isa non-steroidalanti-inflammatorydrug (NSAID ), with analgesic, anti-infl-ammatory,andantipyreticproperties.Itseliminationhalf-time(3 to 5 hours) isle…     

Value of D-Dimers in patients with acute aortic dissection

Objective: To evaluatel the value of D-dimers in patients with acute aortic dissection (AAD). Methods: This study consisted of 16 patients with AAD and 27 non-AAD patients. Serum D-dimets were measured by Sta-Liatest D-DI immunoturbidimetric assay. Results: D-dimer level was higher (P ＜ 0.001) in patients with AAD(7.91 ± 5.52 μg/ml) than that in non- AAD group(1.57±1.24 μg/ml). D-dimer was positive (＞0.4 μg/ml) in all patients with AAD and in 10 control group patients (37%). Among patients with acute AAD, D-dimers tended to be higher in Stanford A than in Stanford B (8.67 ± 4.31 μg/ml vs. 3.24±1.27 μg/ml, P ＜0.01). D-dimer values tended to be higher in more extended disease(3.84 ± 1.65 μg/ml, 8.57 ± 3.58 μg/ml and 11.87 ± 5.69 μg/ml in thoracic aorta, thoracic and abdominal aorta, thoracic and abdominal aorta and iliacal arteries, respectively, P ＜ 0.05 for both 8.57 ± 3.58 and 11.87 ± 5.69 vs. 3.84 ± 1.65 ). Including the control group into the analysis, we found a sensitivity of 100%, a negative predictive value of 100%, and a specificity of 66% and a positive predictive value of 64% for D-dimer in diagnosis of AAD in our patients with suspected AAD. Conclusion: D-dimer was elevated in patients with AAD. A negative D-dimer test result could be useful in excluding AAD.     

Research of combined liver-kidney transplantation model in rats

Objective： To set up a simple and reliable rat model of combined liver-kidney transplantation. Methods： SD rats served as both donors and recipients. 4℃ sodium lactate Ringer＇s was infused from portal veins to donated livers,and from abdominal aorta to donated kidneys, respectively. Anastomosis of the portal vein and the inferior vena cava （IVC） inferior to the right kidney between the graft and the recipient was performed by a double cuff method, then the superior hepatic vena cava with suture. A patch of donated renal artery was anastomosed to the recipient abdominal aorta. The urethra and bile duct were reconstructed with a simple inside bracket. Results： Among 65 cases of combined liver-kidney transplantation, the success rate in the late 40 cases was 77.5%. The function of the grafted liver and kidney remained normal. Conclusion： This rat model of combined liver-kidney transplantation can be established in common laboratory conditions with high success rate and meet the needs of renal transplantation experiment.     

BLOOD PRESSURE CHANGE WITH AGE IN SALT-SENSITIVE TEENAGERS

Objective To observe blood pressure change with age in salt-sensitive teenagers whose salt sensitivity were determined by repeated testing.Methods Salt sensitivity was determined through intravenous infusion of normal saline combined with volume-depletion by oral diuretic furosemide in 55 teenagers. After five years, salt sensitivity was re-examined and subject blood pressure was followed up. Blood pressure changes in salt-sensitive teenagers were compared to that of non-salt sensitive teenagers over five years.Results After 5 years, the repetition rate of salt sensitivity determined by intravenous saline loading is 92.7%. In teenagers with salt sensitivity on the baseline, both the systolic blood pressure increments and increment rates were much higher than non-salt sensitive teenagers (12.7±12.1 mmHg vs. 2.8±5.2 mmHg, P＜ 0.01; 12.2%± 12.0% vs. 2.5% ±4.4%, P＜ 0.001,respectively). There was a similar trend for diastolic blood pressure (8.4 ± 6.4 mmHg vs. 3.7 ± 6.4 mmHg, P = 0.052; 13.2% ±10.6 % vs. 6.8%± 10.1%, P = 0.053, respectively).Conclusions Salt sensitivity determined by intravenous saline loading showed good reproducibility. Blood pressure increments with age were much higher in salt-sensitive teenagers than non-salt sensitive teenagers, especially in terms of systolic blood pressure.     

Acupuncture Combined with Spinal Tui Na for Treatment of Primary Dysmenorrhea in 30 Cases

Objective: To observe the therapeutic effects in acupunture treatment of primary dysmenorrhea combined with spinal Tui Na, and study its mechanism. Methods: Thirty cases of the treatment group were treated by acupuncture combined with spinal Tui Na, and thirty cases in the control group were treated by routine acupuncture. Results: The total effective rate was 93.3% in the treatment group, and 73.3% in the control group, with a significant difference between the two groups (P<0.05). Conclusions: Acupuncture combined with spinal Tui Na has good prospects for treatment of primary dysmenorrhea.     

Luo Lingjie's Experience in Treating Chronic Nephropathy

In treating chronic nephropathy,Luo Lingjie,a chief physician,pays attention to regulating the balance between yin and yang,treating infection if present,and removing pathogenic factors.He prescribes gentle drugs and uses carefully strongly warming-tonifying ones,emphasizes the importance of persuading the patient to persist in treatment with medication and nurse one's health for recuperation,and is good at combined use of TCM and western medicine therapy and brings the merits of various therapies into full play,with obvious theraoeutic effects.     

Dr.Zhang Ren's Experience in the Acupuncture Treatment of Different Diseases with the Same Therapeutic Principle

Dr.Zhang Ren,the chief physician,is the chairman of Shanghai Acupuncture and Moxibustion Association.Having been engaged in medicine for about 40 years,he is experienced in treating various intractable diseases.In his long years of clinical practice,he advocates taking the TCM differentiation as the basis to seek for the acupuncture method for treatment of modern intractable diseases.The author of this essay had the fortune to follow Dr.Zhang in study.The following is a summary of Dr.Zhang's experience in the acupuncture treatment for different intractable diseases with the same therapeutic principle.     

安心颗粒对急诊经皮冠状动脉介入术后生活质量影响的研究

目的：评价使用安心颗粒对急诊经皮冠状动脉介入术（PPCI）术后生活质量的影响.方法：将160例接受PPCI的急性ST段抬高型心肌梗死患者随机分为安心颗粒组（术前顿服安心颗粒8.8g,术后安心颗粒4.4 g/次,每日2次）和对照组（仅接受基础药物治疗）.所有患者均服用阿司匹林、氯吡格雷和阿托伐他汀.分别在入院时、出院前1d、出院后180 d时,应用心肌梗死多维度量表（MIDAS）、中文版SF-36评价量表对患者生活质量评分.并观察术后30 d以内的出血并发症、血小板减少症发生情况.结果：入院时和出院前1d,两组患者的心肌梗死MIDAS、SF-36量表评分比较无差异（P＞0.05）;出院后180 d时,与对照组比较,安心颗粒组MIDAS、SF-36评分明显减低（P＜0.05）;组内与入院时比较,两组出院前1d、出院后180 d时,MIDAS、SF-36评分均降低（P＜0.05）.两组患者在随访期间均无大量出血、少量出血、重度和极重度血小板减少症发生,安心颗粒组有4例、对照组有7例发生不明显出血（P＞0.05）.两组发生轻度血小板减少症的患者数比较无差异（P＞0.05）.结论：PPCI使用安心颗粒,能改善急性ST段抬高型心肌梗死患者的生活质量,且不增加出血风险.     

猪肺磷脂注射液联合经鼻持续气道正压通气对呼吸衰竭早产儿的临床疗效及肌酸激酶同工酶活性的影响

目的 探讨猪肺磷脂注射液联合经鼻持续气道正压通气(NCPAP)对呼吸衰竭早产儿的临床疗效及肌酸激酶同工酶活性(CK-MB)的影响.方法 选取呼吸衰竭早产儿80例,分为观察组和对照组各40例.对照组采用NCPAP给氧治疗,观察组给予NCPAP给氧联合猪肺磷脂气管内给药.观察两组患儿治疗前及治疗12h、24 h后PaO2、PaCO2、血氧饱和度(SaO2)、pH的变化情况,检测治疗前及治疗5d后血清CK-MB水平;评估两组患儿的临床治疗效果.结果 两组患儿PaO2、PaCO2、SaO2、pH比较,差异均有统计学意义(P＜0.05),其中观察组治疗后的PaO2、SaO2、pH均高于对照组,PaCO2则低于对照组.两组的PaO2、SaO2、pH均随观察时间延长而升高(P＜0.05),PaCO2均随观察时间的延长而降低(P＜0.05).观察组治疗有效率为87.5％,显著高于对照组的70.0％ (P ＜0.05).治疗5d后两组患儿血清CK-MB水平均较前降低(P＜0.05),且观察组明显低于对照组(P＜0.05).结论 猪肺磷脂注射液气管内给药联合NCPAP可以显著降低呼吸衰竭早产儿CK-MB的含量,提高治疗有效率,起到很好的呼吸循环支持作用.