综合康复治疗对老年2型糖尿病患者血糖的影响

目的探讨规范的综合康复治疗对老年2型糖尿病患者血糖的影响。方法90例2型糖尿病患者用随机数字表法分为两组,每组45例。对照组按糖尿病常规药物治疗、护理;干预组在对照组的基础上,在康复师指导下完成规范的综合康复治疗。观察两组患者干预前及干预3个月后空腹血糖、餐后2h血糖、糖化血红蛋白及临床疗效、治疗依从性。结果干预后干预组患者的空腹血糖、餐后2h血糖、糖化血红蛋白均低于对照组（P＜0．05）,临床治疗效果及治疗依从性高于对照组（P＜0．05）。结论综合康复治疗对2型糖尿病患者有较好疗效,可降低患者血糖,提高治疗依从性。     

2型糖尿病患者的社区护理效果分析

目的探讨社区护理对2型糖尿病患者的康复作用。方法将2010年3月—2012年3月来我院治疗的社区2型糖尿病患者86例随机分成对照组和观察组各43例,2组均进行基本药物治疗,而观察组在药物治疗基础上加以社区护理干预措施。3个月后,比较2组患者餐前、餐后血糖变化及治疗依从性差异。结果观察组空腹及餐后2 h血糖均比对照组低,且患者对治疗的依从性等方面也比对照组表现得更为良好,差异有显著性(P<0.05)。结论对2型糖尿病患者实施社区护理干预,不仅能有效降低血糖并维持血糖及病情稳定,且能显著提高患者自我保健意识、药物治疗效果及患者的生活质量。     

综合护理干预对妊娠糖尿病患者血糖及治疗依从性的效果观察

目的观察综合护理干预对妊娠糖尿病患者血糖及治疗依从性的效果。方法选取2013年12月至2015年12月本院接收的70例妊娠糖尿病患者,随机分为两组,接受常规护理的35例患者归入对照组,接受综合护理干预的35例患者归入观察组,比较两组的血糖水平及治疗依从性。结果观察组空腹血糖值、餐后2小时血糖值及糖化血红蛋白值下降水平明显优于对照组,P0.05;观察组饮食、运动及用药依从性均明显优于对照组,P0.05。结论对妊娠糖尿病患者实施综合护理干预能有效控制血糖,且能明显提高患者的治疗依从性,确保母婴安全,提高妊娠糖尿病患者的生活质量。     

家庭医生签约对2型糖尿病患者血糖控制效果的影响

目的：观察2型糖尿病患者接受家庭医生签约干预后对血糖控制效果的影响。方法：随机选取2018年7月—2020年7月北京市大兴区西红门医院收治的200例2型糖尿病患者为研究对象，利用红蓝球抽签分组法分为对照组与观察组，各100例。对照组给予社区常规健康管理，观察组开展家庭医生签约模式管理。比较两组患者血糖控制效果、治疗依从性、满意度。结果：干预前，两组空腹血糖、餐后2 h血糖、糖化血红蛋白水平比较，差异无统计学意义(P>0.05)；干预后，观察组空腹血糖、餐后2 h血糖、糖化血红蛋白水平均低于对照组，差异有统计学意义(P<0.05)。观察组按医嘱服药、合理饮食、适当运动、定期复查依从性均高于对照组，差异有统计学意义(P<0.05)。观察组满意度高于对照组，差异有统计学意义(P<0.05)。结论：2型糖尿病患者接受家庭医生签约干预后，血糖控制效果明显，治疗依从性显著升高，整体满意度高。     

糖尿病的社区干预效果分析

目的:探讨糖尿病进行社区干预的效果,为糖尿病患者的社区干预提供依据。方法:将180例2型糖尿病患者随机分为观察组(社区干预组)和对照组(非社区干预组)各90例,随访观察12个月后比较两组患者的空腹血糖(FBG)、餐后2h血糖(PBG)、糖化血红蛋白(HbAlc)、糖尿病知识知晓率、治疗依从性情况。结果:观察组FBG、PBG、HbAlc、糖尿病知识知晓率、治疗依从性情况与对照组比较均有显著性差异(P<0.01),具有统计学意义。结论:对糖尿病患者进行社区干预可以改善血糖水平、提高治疗依从性。     

老年2型糖尿病病人进行健康教育的干预效果观察

目的:观察分析老年2型糖尿病病人进行健康教育的干预效果.方法:选取96例2型糖尿病老年患者,按照是否行健康教育将其分为观察组和对照组,对照组仅给予常规治疗,观察组在常规治疗的同时进行健康教育,观察比较两组患者干预前后血糖指标水平变化情况、糖尿病知识知晓率及治疗依从性.结果:干预后两组患者的FPG、2hPG、HbA1c水平较干预前均明显降低,且干预后观察组患者的FPG、2hPG、HbA1c水平明显低于对照组(P＜0.05).观察组在糖尿病知识知晓率及治疗依从性方面明显优于对照组(P＜0.05).结论:对老年2型糖尿病病人进行健康教育可提高病人对糖尿病的认知,更好地控制血糖,提高患者治疗依从性,值得推广应用.     

全科医学理论指导下社区综合干预对于糖尿病患者血糖控制的效果分析

目的：分析全科医学理论指导下社区综合干预对于糖尿病患者血糖控制的效果。方法：选取2021年2月—2023年2月于祁连社区卫生服务中心接受治疗的糖尿病患者134例作为研究对象,依据随机数字表法分为对照组和观察组,各67例。对照组行常规干预,观察组在对照组基础上实施全科医学理论指导下的社区综合干预,比较两组干预效果。结果：观察组干预后空腹血糖、餐后2 h血糖、糖化血红蛋白水平低于对照组,差异有统计学意义(P<0.05)。观察组干预后糖尿病相关知识知晓程度高于对照组,差异有统计学意义(P<0.05)。观察组干预后定期复诊、遵医嘱用药、合理饮食、合理用药依从性优于对照组,差异有统计学意义(P<0.05)。观察组患者干预后生活质量各项评分高于对照组,差异有统计学意义(P<0.05)。结论：全科医学理论指导下社区综合干预对于糖尿病患者血糖控制的效果较好,可提高患者糖尿病相关知识知晓程度,患者依从性及生活质量高。     

探讨延续性护理干预模式对2型糖尿病患者的应用效果

目的探讨对2型糖尿病患者实施延续性护理模式的效果。方法将在本院接受治疗的70例2型糖尿病患者作为此次研究的对象,按照出院时护理方式的不同分成观察组和对照组,每组包含35例患者,其中对照组患者仅在出院时给予常规的出院指导和健康教育,在此基础上,对观察组患者实施延续性护理,两组患者出院后均进行为期6个月的随访,比较分析两组患者的血糖控制效果、治疗依从性以及生活质量。结果观察组患者的空腹血糖、餐后2h血糖、糖化血红蛋白等血糖评价指标水平均低于对照组,两组差异均存在显著的统计学意义(P0.05);观察组患者出院后的治疗依从性明显高于对照组,差异存在统计学意义(P0.05);观察组患者的健康调查简表各项评价指标评分均优于对照组患者,组间差异显著(P0.05)。结论对2型糖尿病患者实施延续性护理干预模式可以有效提高患者的治疗依从性,改善血糖控制效果以及生活质量,值得进行推广应用。     

浅析综合护理干预对门诊初始胰岛素治疗糖尿病患者的临床效果

目的分析综合护理干预对门诊初始胰岛素治疗糖尿病患者的临床效果。方法选择我院在2017年3月至2018年10月门诊初始胰岛素治疗糖尿病患者120例,按照随机分配原则将其分为2组,对照组60例,观察组60例。对照组患者实施常规护理措施,观察组患者实施综合护理干预措施,对比分析2组患者的血糖控制效果。结果观察组患者的血糖控制效果显著优于对照组(P0.05)。结论对门诊初始胰岛素治疗糖尿病患者实施综合护理干预能够有效控制患者的血糖,提高患者胰岛素治疗的依从性,有利于改善患者的生活质量,具有临床应用价值。     

综合护理干预对糖尿病肾病患者治疗依从性及血糖的影响

目的：探讨综合性护理干预对糖尿病肾病患者治疗依从性及血糖的影响。方法选择2012年—2014年我院确诊为糖尿病肾病的110例患者,随机数字法分成观察组和对照组各55例。对照组进行常规护理,观察组在对照组的基础上进行综合性的护理干预。观察比较2组患者康复情况与依从性程度。结果观察组治疗后无论是空腹血糖浓度及餐后2h血糖浓度下降幅度明显高于对照组;观察组患者依从性优良率为94.55%,明显高于对照组的81.82%,差异有统计学意义（P<0.05）。结论综合护理干预对糖尿病肾病患者康复具有很重要的影响,能有效降低患者血糖,提高治疗依从性,值得临床推广应用。     

Value of D-Dimers in patients with acute aortic dissection

Objective: To evaluatel the value of D-dimers in patients with acute aortic dissection (AAD). Methods: This study consisted of 16 patients with AAD and 27 non-AAD patients. Serum D-dimets were measured by Sta-Liatest D-DI immunoturbidimetric assay. Results: D-dimer level was higher (P ＜ 0.001) in patients with AAD(7.91 ± 5.52 μg/ml) than that in non- AAD group(1.57±1.24 μg/ml). D-dimer was positive (＞0.4 μg/ml) in all patients with AAD and in 10 control group patients (37%). Among patients with acute AAD, D-dimers tended to be higher in Stanford A than in Stanford B (8.67 ± 4.31 μg/ml vs. 3.24±1.27 μg/ml, P ＜0.01). D-dimer values tended to be higher in more extended disease(3.84 ± 1.65 μg/ml, 8.57 ± 3.58 μg/ml and 11.87 ± 5.69 μg/ml in thoracic aorta, thoracic and abdominal aorta, thoracic and abdominal aorta and iliacal arteries, respectively, P ＜ 0.05 for both 8.57 ± 3.58 and 11.87 ± 5.69 vs. 3.84 ± 1.65 ). Including the control group into the analysis, we found a sensitivity of 100%, a negative predictive value of 100%, and a specificity of 66% and a positive predictive value of 64% for D-dimer in diagnosis of AAD in our patients with suspected AAD. Conclusion: D-dimer was elevated in patients with AAD. A negative D-dimer test result could be useful in excluding AAD.     

Research of combined liver-kidney transplantation model in rats

Objective： To set up a simple and reliable rat model of combined liver-kidney transplantation. Methods： SD rats served as both donors and recipients. 4℃ sodium lactate Ringer＇s was infused from portal veins to donated livers,and from abdominal aorta to donated kidneys, respectively. Anastomosis of the portal vein and the inferior vena cava （IVC） inferior to the right kidney between the graft and the recipient was performed by a double cuff method, then the superior hepatic vena cava with suture. A patch of donated renal artery was anastomosed to the recipient abdominal aorta. The urethra and bile duct were reconstructed with a simple inside bracket. Results： Among 65 cases of combined liver-kidney transplantation, the success rate in the late 40 cases was 77.5%. The function of the grafted liver and kidney remained normal. Conclusion： This rat model of combined liver-kidney transplantation can be established in common laboratory conditions with high success rate and meet the needs of renal transplantation experiment.     

APPLICATION OF LORNOXICAM TO PATIENT-CONTROLLED ANALGESIA IN PATIENTS UNDERGOING ABDOMINAL SURGERIES

FOR anesthesiologis s ,treatingpostoperativepainhas alwaysbeen a problem.Althoughopioidshave been provedtobe effective,theirsideeffectscouldnotbeignored.With thedevelopmentofscienceand pharmacology,many drugs with aspectsof satisfactoryanalgesicefficacyand couldbe welltoleratedby patientshave been developed.And lornoxicamisone of them, which isa non-steroidalanti-inflammatorydrug (NSAID ), with analgesic, anti-infl-ammatory,andantipyreticproperties.Itseliminationhalf-time(3 to 5 hours) isle…     

安心颗粒对急诊经皮冠状动脉介入术后生活质量影响的研究

目的：评价使用安心颗粒对急诊经皮冠状动脉介入术（PPCI）术后生活质量的影响.方法：将160例接受PPCI的急性ST段抬高型心肌梗死患者随机分为安心颗粒组（术前顿服安心颗粒8.8g,术后安心颗粒4.4 g/次,每日2次）和对照组（仅接受基础药物治疗）.所有患者均服用阿司匹林、氯吡格雷和阿托伐他汀.分别在入院时、出院前1d、出院后180 d时,应用心肌梗死多维度量表（MIDAS）、中文版SF-36评价量表对患者生活质量评分.并观察术后30 d以内的出血并发症、血小板减少症发生情况.结果：入院时和出院前1d,两组患者的心肌梗死MIDAS、SF-36量表评分比较无差异（P＞0.05）;出院后180 d时,与对照组比较,安心颗粒组MIDAS、SF-36评分明显减低（P＜0.05）;组内与入院时比较,两组出院前1d、出院后180 d时,MIDAS、SF-36评分均降低（P＜0.05）.两组患者在随访期间均无大量出血、少量出血、重度和极重度血小板减少症发生,安心颗粒组有4例、对照组有7例发生不明显出血（P＞0.05）.两组发生轻度血小板减少症的患者数比较无差异（P＞0.05）.结论：PPCI使用安心颗粒,能改善急性ST段抬高型心肌梗死患者的生活质量,且不增加出血风险.     

The comparative studies of the influences of Urapidil and Nicardipine on sino-atrial node function, atrio-ventricular node function and hemodynamics

Objective:To investigate the influences of urapidil and nicardipine on rabbit sinus function,atrio-ventricular node function and hemodynamics.Methods:Thirty-two Angora's rabbits were selected and randomly divided into four groups.U1 group:urapidil 0.25 mg/kg;U2 group:urapidil 0.5 mg/kg;N1 group:nicardipine 10 μg/kg;N2 group:nicardipine 20 μg/kg.All these medicine were administrated within 30 seconds.Measurements were taken before and after the administration of urapidil or nicardipine for the following data:mean blood pressure(MAP),heart rate(HR),sino-atrial conduction time(SACT),maximal sinoatrial recovery time(SNRTmax)corrected sinus node recovery time(CSNRT),index of sinus node recovery time(SNRTI),Wenckebach A-V conduction frequency (WB),and P-R interval.Results:Significant MAP and HR changes were identified in all of the four groups before and after administration of both urapidil and nicardipine.No significant changes could be found in the rest of the parameters.Intergroup analysis showed that SACT and CSNRT of N1 and N2 groups were shorter than those of the U2 group(P＜0.01);the MAP decreased(P＜0.01)and the HR increased drastically(P＜0.01).Conclusions:Neither urapidil(0.25 mg/kg,0.5 mg/kg)nor nicardipine(10μg/kg,20μg/kg)has any significant influence on rabbit sinus function or rabbit atrio-ventricular node function.Nicardipine could be a better choice than urapidil for parafunctional sinus node patients.     

Expression of OPGmRNA and ODFmRNA in the patients of hip fracture due to osteoporosis

Objective：To investigate the gene expression of osteoprotegerin（OPG） and osteoclast differentiation factor（ODF） in the bone tissue of patients with hip fracture due to osteoporosis. Methods：OPGmRNA and ODFmRNA in the bone tissue in 50 cases of osteoporosis sufferers（over 50 years old） with hip fracture（Observer Group） and 30 cases of hip facture sufferers with no osteoporosis（Control group） were analyzed with the Semi-Quantitative RT-PCR method. Results：The mRNA expressed of ODF, OPG were both high in the patients with hip fracture. In the control group, the expression of OPG mRNA was observed, while the expression of ODF mRNA was very slight. Conclusion：Aged patients contained all signals including OPG, ODF that are essential for inducing osteoclastogenesis and promoting bone resorption.     

The clinicopathological and immuohistochemical analysis of solid-pseudopapillary tumor of the pancreas： report of 9 cases

Objective：To investigate the clinical features, pathological characteristics and immunophenotype of solid-pseudopapillary tumor of the pancreas（SPTP）. Methods：Nine surgically treated cases of SPTP were retrospectively reviewed. Hematoxylin and Eosin（HE） staining and immunohistochemical staining were used to analyze all cases, and the general clinical data was collected. Results：Six patients were asymptomatic except for a palpable mass. Two patients complained of vague-epigastric pain. One patient appeared jaundice. The tumor was encapsulated and solid tissues alternately with cystic tissues. Histologically, the histological structure of solid portion was pseudopapillary with a fibrovascular core. Tumor cells were uniform and medium-sized which were arranged in sheets ets or nests or pseudopapillary patterns. Immunohistochemical studies demonstrated that SPTP proved positive in vimentin（9/9 cases）, AAT（9/9 cases）, NSE（9/9 cases）, ACT（7/9 cases）, CK20（2/9 cases）, CgA（1/9 cases）, S-100（3/gcases）, PR（4/gcases）, Syn（3/9 cases） and CD56（5/9cases）, negative in CEA and ER. Conclusion：SPTP is a tumor predominantly occurring in young women frequently without special symptoms. This tumor has various characteristical histological patterns with different immunophenotype.     

Acupuncture Combined with Spinal Tui Na for Treatment of Primary Dysmenorrhea in 30 Cases

Objective: To observe the therapeutic effects in acupunture treatment of primary dysmenorrhea combined with spinal Tui Na, and study its mechanism. Methods: Thirty cases of the treatment group were treated by acupuncture combined with spinal Tui Na, and thirty cases in the control group were treated by routine acupuncture. Results: The total effective rate was 93.3% in the treatment group, and 73.3% in the control group, with a significant difference between the two groups (P<0.05). Conclusions: Acupuncture combined with spinal Tui Na has good prospects for treatment of primary dysmenorrhea.     

Luo Lingjie's Experience in Treating Chronic Nephropathy

In treating chronic nephropathy,Luo Lingjie,a chief physician,pays attention to regulating the balance between yin and yang,treating infection if present,and removing pathogenic factors.He prescribes gentle drugs and uses carefully strongly warming-tonifying ones,emphasizes the importance of persuading the patient to persist in treatment with medication and nurse one's health for recuperation,and is good at combined use of TCM and western medicine therapy and brings the merits of various therapies into full play,with obvious theraoeutic effects.     

Dr.Zhang Ren's Experience in the Acupuncture Treatment of Different Diseases with the Same Therapeutic Principle

Dr.Zhang Ren,the chief physician,is the chairman of Shanghai Acupuncture and Moxibustion Association.Having been engaged in medicine for about 40 years,he is experienced in treating various intractable diseases.In his long years of clinical practice,he advocates taking the TCM differentiation as the basis to seek for the acupuncture method for treatment of modern intractable diseases.The author of this essay had the fortune to follow Dr.Zhang in study.The following is a summary of Dr.Zhang's experience in the acupuncture treatment for different intractable diseases with the same therapeutic principle.