新型敷料在糖尿病足护理应用中的效果观察

目的 探讨新型敷料在糖尿病足护理中的应用效果.方法 随机将83例糖尿病足患者分为两组,实验组采用新型敷料进行换药,对照组采用传统敷料进行换药.对两组局部溃疡的愈合率、愈合时间和换药次数进行比较.结果 实验组平均愈合时间较对照组缩短,换药次数低于对照组,且实验组局部溃疡愈合率明显高于对照组,两组之间有统计学差异（P＜0.05）.结论 新型伤口护理敷料能最大限度地减少糖尿病足伤口及周围皮肤的损伤,促进肉芽组织生长,降低截肢率,减少致残率,提高患者的生活质量.     

新型伤口护理敷料在治疗糖尿病足应用中的临床研究

目的:探讨新型伤口护理敷料在治疗糖尿病足中的应用。方法:将50例住院糖尿病足患者,随机分为两组:实验组24例,对照组26例,实验组采用新型伤口护理敷料进行换药,对照组采用常规敷料进行换药。并对两组局部溃疡的愈合率、愈合时间和换药次数进行比较。结果:实验组局部溃疡愈合率明显高于对照组(P<0.05),平均愈合时间较对照组明显缩短(P<0.05),且换药次数明显少于对照组(P<0.05)。结论:新型伤口护理敷料在治疗糖尿病足中的应用优于常规敷料,能最大限度地减少对伤口和周围皮肤的损伤促进肉芽组织生长,缩短愈合时间,减少换药次数,减少致残率,提高生活质量。     

速愈乐愈伤敷料用于糖尿病足换药效果观察

目的 探讨速愈乐愈伤敷料用于糖尿病足换药疗效的影响.方法 将40例糖尿病足患者随机分为观察组和对照组,每组20例.观察组采用速愈乐愈伤敷料换药治疗,对照组采用胰岛素和庆大霉素混合液喷洒伤口换药治疗,观察两组糖尿病足的治疗有效率、愈合时间、截肢率、患者满意率、住院费用.结果 观察组治疗有效率、愈合时间、截肢率、患者满意率优于对照组,两组差异均有统计学意义(P＜0.05).结论 速愈乐愈伤敷料用于糖尿病足换药能加速糖尿病足肉芽组织的生长,缩短伤口愈合时间,提高了治疗的有效率,减少致残率,在临床有着重要意义.     

藻酸盐敷料对糖尿病足部窦道伤口治疗的疗效观察

目的:观察采用藻酸盐敷料治疗糖尿病足部窦道感染伤口的临床治疗效果。方法:回顾性分析50例糖尿病足部感染性窦道伤口患者分为观察组和对照组各25例,按照窦道伤口基本情况相当的条件下,对照组采用传统换药法,观察组采用康惠尔藻酸盐敷料换药的方法。结果:在疗效、换药次数、伤口临床愈合时间、不良反应方面比较观察组明显优于对照组,而且患者的满意度高,两组之间比较差异有统计学意义(P<0.05)。结论:在糖尿病足部感染形成窦道治疗的过程中,通过严格的控制血糖及抗感染治疗,同时采用康惠尔藻酸盐敷料换药能够明显减少窦道换药次数,临床愈合时间明显缩短,伤口不良反应小,提高临床治疗效果以及患者满意度。     

封闭型敷料在伤口护理上的疗效观察

目的:观察封闭敷料在伤口愈合中的作用。方法:将68例计81处伤口按随机原则分为两组,伤口护理过程中,对照组伤口采用传统敷料换药,观察组采用封闭型敷料换药,比较两组创面恢复有效率、愈合时间、换药次数及时间。结果:观察组伤口愈合总有效率为100.0%,对照组为85.37%;观察组伤口平均愈合时间及换药次数与时间明显少于对照组,差异有统计学意义(P0.05)。结论:在有效处理伤口的基础上,封闭型敷料更有助于伤口愈合,减少换药次数。     

两种换药方法对卧床患者臀裂处皮肤损伤的临床效果观察

目的 观察水胶体敷料用于治疗卧床患者臀裂处皮肤损伤的效果.方法 将70例臀裂处皮肤损伤患者分为观察组和对照组各35例.观察组采用多爱肤水胶体敷料贴于患处;对照组采用传统油纱敷料外敷患处.观察对比两组患者的换药次数、臀裂处伤口的愈合时间、敷料及伤口被大小便污染的次数.结果 观察组患者的换药次数、臀裂处伤口的愈合时间均优于对照组,敷料及伤口被大小便污染的次数少于对照组,差异有统计学意义（P ＜ 0.05）.结论 水胶体敷料治疗臀裂处皮肤损伤效果确切,具有疗程短、有效避免大小便污染、减轻患者痛苦、减少护理工作量等优点,值得临床推广应用.     

探讨并分析伤口护理敷料对感染伤口换药的疗效

目的探讨并分析伤口护理敷料对感染伤口换药的临床疗效。方法选择我院2017年8月至2018年8月收治的141例患者(184处伤口)作为本次的研究对象,按照患者入院的先后次序将其随机分为观察组与对照组,观察组71例,对照组70例。对照组患者给予传统换药模式进行换药,观察组则给予伤口护理敷料处理感染的伤口,比较两组患者的治疗效果。结果经过治疗后,观察组的伤口治疗有效率为94.37%,明显高于对照组的68.57%,P0.05,具有统计学意义。结论采用伤口护理敷料的方式进行治疗,不仅可以减少换药的次数,还能观察患者的疼痛程度。根据患者的不同需求,治疗时可采用相应的敷料进行治疗。且敷药过程中能够保持伤口的湿润,从而提高其愈合率,能够有效减少患者的住院时间,值得应用与推广。     

新型敷料在糖尿病足溃疡中的临床应用

目的探讨新型敷料在治疗糖尿病足溃疡中的作用和效果。方法将46例糖尿病足溃疡患者随机分为观察组和对照组,分别使用新型敷料和传统敷料,比较两组治疗前后的踝肱指数(ABI)、治愈情况、换药次数及愈合时间。结果观察组患者总有效率和治疗前后ABI值明显高于对照组,观察组患者换药次数和创面愈合时间明显少于对照组,两者比较差异有统计学意义(P<0.05)。结论治疗糖尿病足溃疡时,不同时期使用不同的新型敷料能加速创面的愈合,减少患者的痛苦。     

压疮患者使用新型伤口敷料护理分析

目的分析新型伤口敷料护理在压疮患者中的应用价值。方法 2015年1月-2016年7月收集住院患者中压疮患者100例,按压疮护理方法不同随机分为对照组(常规护理)和观察组(新型伤口敷料护理)。记录两组患者住院时间、压疮愈合时间、换药次数;观察两组患者恢复情况,调查护理满意度。结果观察组患者换药次数较对照组少,住院时间和愈合时间均较对照组短;观察组所有患者均在出院前愈合,对照组中1例Ⅲ期压疮未见好转,后申请用新型伤口敷料见好转;观察组护理满意率(92.00%)较对照组(76.00%)高(P<0.05)。结论新型伤口敷料用于压疮护理中,能促进压疮愈合,减少换药次数,尤其适合Ⅲ期压疮,患者给予高度认可。     

洁悠神配合湿性敷料在伤口护理中的疗效观察

目的 探讨洁悠神配合湿性敷料在伤口护理中的疗效.方法 选取2015年4月~2016年3月在本院接受治疗的60例伤口患者的临床资料进行研究,按照护理方法的不同将患者分为对照组和观察组,各30例.给予对照组患者传统换药方法进行护理,给予观察组患者洁悠神配合湿性敷料进行护理,观察两组患者护理效果.结果 观察组患者的总有效率为93.33%明显高于对照组患者56.67%的总有效率,差异有统计学意义(P<0.05);观察组患者伤口愈合时间、均用药费用、换药次数等指标明显少于对照组,差异有统计学意义(P<0.05).结论洁悠神配合湿性敷料应用于伤口护理中能够有效控制伤口感染,缩短患者住院时间,提高护理满意度.     

Value of D-Dimers in patients with acute aortic dissection

Objective: To evaluatel the value of D-dimers in patients with acute aortic dissection (AAD). Methods: This study consisted of 16 patients with AAD and 27 non-AAD patients. Serum D-dimets were measured by Sta-Liatest D-DI immunoturbidimetric assay. Results: D-dimer level was higher (P ＜ 0.001) in patients with AAD(7.91 ± 5.52 μg/ml) than that in non- AAD group(1.57±1.24 μg/ml). D-dimer was positive (＞0.4 μg/ml) in all patients with AAD and in 10 control group patients (37%). Among patients with acute AAD, D-dimers tended to be higher in Stanford A than in Stanford B (8.67 ± 4.31 μg/ml vs. 3.24±1.27 μg/ml, P ＜0.01). D-dimer values tended to be higher in more extended disease(3.84 ± 1.65 μg/ml, 8.57 ± 3.58 μg/ml and 11.87 ± 5.69 μg/ml in thoracic aorta, thoracic and abdominal aorta, thoracic and abdominal aorta and iliacal arteries, respectively, P ＜ 0.05 for both 8.57 ± 3.58 and 11.87 ± 5.69 vs. 3.84 ± 1.65 ). Including the control group into the analysis, we found a sensitivity of 100%, a negative predictive value of 100%, and a specificity of 66% and a positive predictive value of 64% for D-dimer in diagnosis of AAD in our patients with suspected AAD. Conclusion: D-dimer was elevated in patients with AAD. A negative D-dimer test result could be useful in excluding AAD.     

Research of combined liver-kidney transplantation model in rats

Objective： To set up a simple and reliable rat model of combined liver-kidney transplantation. Methods： SD rats served as both donors and recipients. 4℃ sodium lactate Ringer＇s was infused from portal veins to donated livers,and from abdominal aorta to donated kidneys, respectively. Anastomosis of the portal vein and the inferior vena cava （IVC） inferior to the right kidney between the graft and the recipient was performed by a double cuff method, then the superior hepatic vena cava with suture. A patch of donated renal artery was anastomosed to the recipient abdominal aorta. The urethra and bile duct were reconstructed with a simple inside bracket. Results： Among 65 cases of combined liver-kidney transplantation, the success rate in the late 40 cases was 77.5%. The function of the grafted liver and kidney remained normal. Conclusion： This rat model of combined liver-kidney transplantation can be established in common laboratory conditions with high success rate and meet the needs of renal transplantation experiment.     

BLOOD PRESSURE CHANGE WITH AGE IN SALT-SENSITIVE TEENAGERS

Objective To observe blood pressure change with age in salt-sensitive teenagers whose salt sensitivity were determined by repeated testing.Methods Salt sensitivity was determined through intravenous infusion of normal saline combined with volume-depletion by oral diuretic furosemide in 55 teenagers. After five years, salt sensitivity was re-examined and subject blood pressure was followed up. Blood pressure changes in salt-sensitive teenagers were compared to that of non-salt sensitive teenagers over five years.Results After 5 years, the repetition rate of salt sensitivity determined by intravenous saline loading is 92.7%. In teenagers with salt sensitivity on the baseline, both the systolic blood pressure increments and increment rates were much higher than non-salt sensitive teenagers (12.7±12.1 mmHg vs. 2.8±5.2 mmHg, P＜ 0.01; 12.2%± 12.0% vs. 2.5% ±4.4%, P＜ 0.001,respectively). There was a similar trend for diastolic blood pressure (8.4 ± 6.4 mmHg vs. 3.7 ± 6.4 mmHg, P = 0.052; 13.2% ±10.6 % vs. 6.8%± 10.1%, P = 0.053, respectively).Conclusions Salt sensitivity determined by intravenous saline loading showed good reproducibility. Blood pressure increments with age were much higher in salt-sensitive teenagers than non-salt sensitive teenagers, especially in terms of systolic blood pressure.     

Development on Adjustable Calibration Marker for Shock Wave Focus

Shock wave lithotripsy （SWL） is a treatment of choice for upper urinary stones. However, this procedure is inappropriate for obese patients because the focus is often unable to reach the target owing to the limited focal distance in shock wave source. Although treating such patients in a blast path may increase the application length of shock wave source, it＇s difficult to find this path on the lithotripter monitor. For this reason, we invented an adjustable calibration marker in order to set an effective focus in the shock wave hath.     

Study on the TCM Pathogenesis of Angiopathic Complications of Type II Diabetes

Excess production of reactive oxygen species(ROS)of mitochondrion mediated by hyperglycemia is the common pathogenesis of angiopathic complications of diabetes.TCM holds that the damp from the dysfunction of spleen.kidney and liver is the causative factor of complications of diabetes.This is similar to the mechanism of Ros resulting in angiopathic complications of diabetes.When the angiopathic complications of type II diabetes mellitus(T2DM)are difierentiated as caused by turbid damp in TCM can be explained as ROS.Since the obstruction of pathogenic damp in channels and collaterals is said to be the main pathogenesis,the treating principle should be dissolving the damp to remove the obstruction.     

Leptin, Ghrelin and TNF-α before and after Hypo-caloric Traditional Chinese Diet and Auricular Acupuncture

INTRODUCTION Obesity is a complex emergent problem, which can be possibly solved not only by the diet but also by the life style and promotion of a constant physical exercise. 1, 2 No doubt careful attentions must be given to the nutritional condition of obese people, the dietary habits, the somatic build (i.e. distribution of fat mass) and the organic functions linked to formation of the fat mass. All the parameters should be constantly monitored before, during and after a diet treatment. 3, 4, 5     

Relationship between Dysglycemia and Carotid Atherosclerosis in Tibetan Population

People with dysglycemia are at high risk for atherosclerotic diseases. This study aims at investigating the atherosclerotic vascular damage in dysglycemia and its metabolic origin in Tibetan population.     

APPLICATION OF LORNOXICAM TO PATIENT-CONTROLLED ANALGESIA IN PATIENTS UNDERGOING ABDOMINAL SURGERIES

FOR anesthesiologis s ,treatingpostoperativepainhas alwaysbeen a problem.Althoughopioidshave been provedtobe effective,theirsideeffectscouldnotbeignored.With thedevelopmentofscienceand pharmacology,many drugs with aspectsof satisfactoryanalgesicefficacyand couldbe welltoleratedby patientshave been developed.And lornoxicamisone of them, which isa non-steroidalanti-inflammatorydrug (NSAID ), with analgesic, anti-infl-ammatory,andantipyreticproperties.Itseliminationhalf-time(3 to 5 hours) isle…     

安心颗粒对急诊经皮冠状动脉介入术后生活质量影响的研究

目的：评价使用安心颗粒对急诊经皮冠状动脉介入术（PPCI）术后生活质量的影响.方法：将160例接受PPCI的急性ST段抬高型心肌梗死患者随机分为安心颗粒组（术前顿服安心颗粒8.8g,术后安心颗粒4.4 g/次,每日2次）和对照组（仅接受基础药物治疗）.所有患者均服用阿司匹林、氯吡格雷和阿托伐他汀.分别在入院时、出院前1d、出院后180 d时,应用心肌梗死多维度量表（MIDAS）、中文版SF-36评价量表对患者生活质量评分.并观察术后30 d以内的出血并发症、血小板减少症发生情况.结果：入院时和出院前1d,两组患者的心肌梗死MIDAS、SF-36量表评分比较无差异（P＞0.05）;出院后180 d时,与对照组比较,安心颗粒组MIDAS、SF-36评分明显减低（P＜0.05）;组内与入院时比较,两组出院前1d、出院后180 d时,MIDAS、SF-36评分均降低（P＜0.05）.两组患者在随访期间均无大量出血、少量出血、重度和极重度血小板减少症发生,安心颗粒组有4例、对照组有7例发生不明显出血（P＞0.05）.两组发生轻度血小板减少症的患者数比较无差异（P＞0.05）.结论：PPCI使用安心颗粒,能改善急性ST段抬高型心肌梗死患者的生活质量,且不增加出血风险.     

The comparative studies of the influences of Urapidil and Nicardipine on sino-atrial node function, atrio-ventricular node function and hemodynamics

Objective:To investigate the influences of urapidil and nicardipine on rabbit sinus function,atrio-ventricular node function and hemodynamics.Methods:Thirty-two Angora's rabbits were selected and randomly divided into four groups.U1 group:urapidil 0.25 mg/kg;U2 group:urapidil 0.5 mg/kg;N1 group:nicardipine 10 μg/kg;N2 group:nicardipine 20 μg/kg.All these medicine were administrated within 30 seconds.Measurements were taken before and after the administration of urapidil or nicardipine for the following data:mean blood pressure(MAP),heart rate(HR),sino-atrial conduction time(SACT),maximal sinoatrial recovery time(SNRTmax)corrected sinus node recovery time(CSNRT),index of sinus node recovery time(SNRTI),Wenckebach A-V conduction frequency (WB),and P-R interval.Results:Significant MAP and HR changes were identified in all of the four groups before and after administration of both urapidil and nicardipine.No significant changes could be found in the rest of the parameters.Intergroup analysis showed that SACT and CSNRT of N1 and N2 groups were shorter than those of the U2 group(P＜0.01);the MAP decreased(P＜0.01)and the HR increased drastically(P＜0.01).Conclusions:Neither urapidil(0.25 mg/kg,0.5 mg/kg)nor nicardipine(10μg/kg,20μg/kg)has any significant influence on rabbit sinus function or rabbit atrio-ventricular node function.Nicardipine could be a better choice than urapidil for parafunctional sinus node patients.