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1.
Muhammad Nabeel Ghayur Anwarul Hassan Gilani 《European Food Research and Technology》2007,224(4):477-481
In this study, we describe the tracheal-relaxant and tocolytic activities of the methanol (ME) and aqueous (AQ) crude extracts
of ginger (rhizome of Zingiber officinale) in an attempt to rationalize its traditional use in disorders of airways and uterine hyperactivity. Both of the ginger extracts
dose-dependently relaxed K+ (80 mM) and carbachol (CCh, 1 μM)-induced contractions with more potency against K+, similar to that elicited by verapamil, a Ca2+ channel blocker. In isolated uterine preparations, the extracts suppressed the K+-induced contractions with respective EC50 values of 0.03 mg/ml (0.02–0.05, 95% CI) and 0.05 mg/ml (0.04–0.06). Activity-directed fractionation of AQ yielded an organic
and an aqueous fraction with the activities concentrated in the former. Both the crude extracts were found safe in mice up
to the oral dose of 5 g/kg when tested for acute toxicity for 24 h. The study shows that ginger possesses tracheal and uterine
smooth muscle relaxant activity, possibility mediated via Ca2+ channel blockade, justifying its use in disorders such as asthma, cough as well as in dysmenorrhoea and uterine and menstrual
spasms and congestion. 相似文献
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目的:基于模式生物秀丽隐杆线虫(以下简称线虫)探究铁皮石斛叶多糖的抗衰老能力。方法:采用含不同质量浓度(0.5、1.0、2.0 mg/mL)铁皮石斛叶多糖的大肠埃希氏菌OP50菌液每天饲喂线虫,以饲喂大肠埃希氏菌OP50菌液组作为空白对照,观察铁皮石斛叶多糖对线虫寿命、生殖能力、运动能力和应激能力的影响,同时测定线虫体内活性氧水平及抗氧化酶的酶活力,分析铁皮石斛叶多糖对线虫体内抗氧化能力的影响。结果:与空白对照组线虫相比,在本实验考察的质量浓度范围内,铁皮石斛叶多糖均可延长线虫的寿命,提高其运动、应激能力,同时不会损害线虫的生殖能力,并且能有效提高过氧化氢酶和超氧化物歧化酶的活力,显著降低线虫体内丙二醛含量(P<0.05)。结论:铁皮石斛叶多糖可能通过提高线虫抗氧化酶活力及提高线虫抗应激能力,降低线虫体内活性氧水平并减缓细胞氧化损伤,进而发挥延长线虫寿命的功效。 相似文献
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Yasodha Sivasothy Wong Keng Chong Abdul Hamid Ibrahim M. Eldeen Shaida Fariza Sulaiman Khalijah Awang 《Food chemistry》2011
The essential oils obtained by hydrodistilation of the leaves and rhizomes of Zingiber officinale var. rubrum Theilade were analysed by capillary GC and GC–MS. Forty-six constituents were identified in the leaf oil, while 54 were identified in the oil from the rhizomes. The leaf oil was clearly dominated by β-caryophyllene (31.7%), while the oil from the rhizomes was predominantly monoterpenoid, with camphene (14.5%), geranial (14.3%), and geranyl acetate (13.7%) the three most abundant constituents. The evaluation of antibacterial activities using the micro-dilution technique revealed that both the leaf and rhizome oils were moderately active against the Gram-positive bacteria Bacilluslicheniformis, Bacillus spizizenii and Staphylococcus aureus, and the Gram-negative bacteria Escherichia coli, Klebsiella pneumoniae and Pseudomonas stutzeri. 相似文献
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Toshiya Masuda Akiko Jitoe Tom J. Mabry 《Journal of the American Oil Chemists' Society》1995,72(9):1053-1057
New antioxidants, cassumunarins A, B, and C, were isolated from the rhizomes ofZingiber cassumunar, and the structures were determined by spectroscopic methods to be complex curcuminoids. The antixidant efficiency of cassumunarins
was determined by inhibitory activity of autoxidation of linoleic acid in a buffer-ethanol system. The anti-inflammatory effect
was measured by inhibition of edema formation on mouse ear induced by 12-O-tetradecanoylphorbol-13-acetate. Both types of activities were stronger for the cassumunarins than for the curcumin.
Visiting scholar at University of Texas (October 1992–September 1993). 相似文献
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目的观察铁皮石斛对妊娠大鼠及胚胎发育的影响。方法将妊娠SD大鼠分为溶剂对照组及625、1250、2500 mg/kg铁皮石斛组。于妊娠的第7~16 d经口给予孕鼠不同剂量的铁皮石斛。妊娠第20 d颈椎脱臼法处死孕鼠并解剖,取出子宫称重,检查活胎、吸收胎和死胎数,逐个记录活胎鼠的体重、身长、胎盘重量。每窝检查约一半存活胎鼠的内脏,其余存活胎鼠检查骨骼。结果 3种剂量对妊娠大鼠无明显毒性。其中2500 mg/kg组胎鼠体重与对照组比较有统计学差异(P0.05),胎鼠其余各项指标与对照组比较,差异均无统计学意义(P0.05)。结论铁皮石斛对妊娠母鼠无明显影响,未见致胎鼠畸形作用,可引起胎鼠体重增加。 相似文献
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茗荷中食用红色素提取及稳定性研究 总被引:4,自引:1,他引:3
采用单因素分析和正交试验L16(45),确定了提取茗荷红色素的最佳工艺条件,并分析了茗荷红色素的稳定性.结果表明,最佳工艺条件为:料液比为1∶20,提取温度为50℃,提取剂的pH值为1,提取时间为120min.茗荷红色素的耐热性好,耐光性较差,在酸性条件、氧化剂和蔗糖、VC、淀粉和柠檬酸中稳定性较好;在还原剂、苯甲酸钠和山梨酸钾中稳定性较差;色素对金属离子的稳定性较高,Fe3 、Al3 、Ca2 对色素有增色效果,Cu2 使色素溶液变色,Mg2 、Na 和K 对色素无不良影响. 相似文献
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