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气候变化对蚊媒病毒性疾病流行病学影响研究现状 总被引:1,自引:0,他引:1
蚊虫传播的登革热、圣路易斯脑炎、流行性乙型脑炎等病毒性疾病严重威胁着人类健康。气候变化诸如气温和降雨量的变化,可改变蚊虫地理分布、影响蚊虫生长发育和病毒在蚊虫体内的繁殖速度,也改变着疾病流行和传播的特征。现就气候变化对蚊媒病毒性疾病影响的研究进展进行介绍,并综述蚊媒病毒性疾病的流行趋势,试图全面了解气候变化之下蚊虫传播的病毒性疾病流行病学现状。 相似文献
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Global health concerns about the health of the global population and the concepts of global health are gradually being accepted by all of the countries in the world.China health and quarantine at points of entry(POEs) is an integral part of global health,and its duty of prevention and control of the communicable diseases in POEs is consistent with the duty of global health to promote the health of global population.Under the principle of "prevention first",health and quarantine organ carries out the work of disease prevention and control and international travel health care,the reinforcement of core capacity at POEs,and focuses on human rights protection.All the same,there are some gaps with the requirements of global health,such as the inadequate of health promotion planning capacity,ethics awareness and legal protection.The future work of health and quarantine should change ideas on communicable diseases prevention at POEs,focus more on ethical consideration,and should optimize system architecture and human resources,strengthen cooperation,maintain core capacity at POEs,thus to build points of entry public health system with Chinese characteristics,meanwhile to apply the concepts of global health deeply into every aspects of health and quarantine at POEs. 相似文献
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目的 探索NT-proBNP在腹膜透析患者容量负荷评估中的临床应用价值.方法 选取腹膜透析(PD)患者42例为研究对象,进入观察前个体化透析处方,监测受试患者的血NT-proBNP、Alb、Hb、Ca2+、P3+、PTH、SBP、DBP、Kt/V、LVDd、LVPWT、LVST、EF、CTR等,分析NT-proBNP与各项指标的相关性.结果 腹透患者NT-proBNP水平[心衰组与非心衰组分别为(15171.30±14185.87),(2837.04±2167.14)较对照组(141.25±87.20)明显升高(P<0 05)];患者血压与NT-proBNP水平呈显著正相关(SBP:r=0.468,P<0.05;DBP:r=0.509,P<0.05);NT-proBNP水平与ALB、HB呈负相关(r=-0.206、-0.311),与CHOL呈正相关(r=0 34);心衰组(1.39±0.26)与非心衰组(1.73±0.15)腹透患者KT/V与血NT-proBNP水平呈正相关(r=0.270);CTR在腹透患者中升高,与NT-proBNP呈正相关(r=0.557,P<0.01);LVDd在心衰组与非心衰组有增高[女性心衰组与非心衰组分别为(60.83±5.85)、(47.17±5.49),与对照组(43.33±5.65)相比,差异有统计学意义(P<0.05);男性心衰组与非心衰组分别为(66.17±6.94)、(52.67±2.58),与对照组(50.67±2.88)相比,差异有统计学意义(P<0.05)];心衰组EF明显下降(P=0.009);LVPWT、LVST在腹透患者之间比较差异无统计学意义,但与对照组比较差异有统计学意义(P=0.080、0.054).血NT-proBNP水平与LVDd(女性r=0.398,男性r=0.784,P<0.01),LVPWT(r=0.456,P<0.05),LVST(r=0.442,P<0.05)均呈正相关,与EF呈负相关(r=-0.363).结论 腹膜透析患者血NT-proBNP水平明显升高,升高的程度与心功能分级有关,可作为评估腹膜透析患者心功能及容量负荷的指标. 相似文献
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目的构建含有克里米亚-刚果出血热病毒特征序列的克隆载体。方法设计RT-PCR引物及反应体系,从克里米亚-刚果出血热病毒RNA中扩增获得目的序列,进行分离纯化和回收,将纯化的扩增片段与pMD18-T载体进行连接,进行酶切鉴定与测序鉴定。结果确定检测克里米亚-刚果出血热病毒一步法RT-PCR的反应条件及体系,引物终浓度为400 nmol/L,反应条件为:50℃30 min,94℃4 min,94℃30s,57℃30 s,72℃30 s,35cycles.成功将CCHF的特征序列片段克隆,pMD18-T载体经DNA测序鉴定正确。结论构建的pMD18-CCHF质粒,可用于克里米亚-刚果出血热病毒RT-PCR实验的阳性对照。 相似文献
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