国内外有关神经科学方面的杂志简介

引言在搜索下列期刊时,已部分的阅读了其发表的文章,深深地感觉到20世纪最后10年由于脑科学研究的长足进展,给神经科学领域带来的辉煌成绩!     

非酒精性脂肪性肝病患者血清瘦素和脂联素与胰岛素抵抗的关系

Objective To investigate the serum leptin and adiponectin levels in nonalcoholic fatty liver disease (NAFLD) patients, and their relationship with insulin resistance. Methods A total of 120 cases were enrolled and divided into two groups: NAFLD group (n = 60) and normal control group (n = 60). The serum levels of leptin and adiponectin were measured by EL1SA. The body mass index (BMI), waist-to-hip ratio (WHR), triglyceride (TG), total cholesterol (Tchol), high-density lipoprotein cholesterol (HDL-C), aspartate aminotransferase (AST), alanine aminotransferase (ALT), gamma-glutamyl transpeptidase (GGT), fasting blood glucose (FBG) and HOMA-IR (homeostasis model assessment insulin resistance) were detected and analyzed. Results Compared with control group, the serum leptin level in NAFLD group was Significantly higher [(12.37 ± 1.99) μg/Lvs (5.20 ± 1.03)μg/L,P<0.01], while the serum adiponectin level was significantly lower [(12.69 ± 2.83) mg/L vs (22.83 ± 4.61) mg/L, P < 0.01]. HOMA-IR was also much higher in NAFLD group than that in control group[(4.86 ± 0.63) vs (1.91 ± 0.41), P < 0.01]. Logistic regression analysis showed that leptin was positively correlated with WHR ( P = 8.175, P < 0.01), HOMA-IR ( P = 0.974, P < 0.01 ), FBG ( β = 0.564, P < 0.01). In contrast, adiponectin inversely associated with HOMA-IR ( β = -0.495, P < 0.01 ) and BMI ( β = -0.314, P < 0.01) respectively. Conclusions The increased serum leptin level and decreased serum adiponectin level in NAFLD patients independently associated with HOMA-IR.     

全国省级疾病预防控制中心教育培训管理现状及新职工培训需求调查分析

目的 分析全国省级CDC 2012-2014年教育培训管理现状及新职工培训需求,为今后做好疾控领域教育培训工作提供参考和依据。方法 采用问卷调查,对我国32个省级和5个计划单列市(大连市、青岛市、宁波市、厦门市、深圳市)级CDC,收集、分析其教育培训管理情况、新职工岗前培训开展情况及新职工培训需求等。结果 36个CDC共有156名教育培训管理人员,中级及以上职称所占比例最高(70%);培训硬件配备各地间差别较大;2014年共有各类教育培训师资1214人,公共卫生相关专业技术领域师资占66%;2012-2014年,全国36个CDC共对5084人次新职工开展了岗前培训,投入约75万元;新职工培训需求率为99.5%,74%的调查对象认为2~5 d是最合适的培训时间,79%的新职工认为实践操作是最适合的培训方法。结论 全国各省级CDC教育培训机构设置有待明确,管理人员队伍需要补充,应不断增加培训经费投入、完善培训配套的场地、食宿、师资等相关软、硬件配备,重视疾控机构人员尤其是新职工的教育培训工作。     

沈阳市不同职业人群脂肪肝的流行现状分析

目的探讨不同职业人群脂肪肝的流行现状。方法纳入6992名健康体检者为研究对象,职业来源包括2家医院的医护人员、3家银行的职员、3个工厂的工人及机关干部,所有研究对象均接受彩超检查。结果 6992名研究对象中,其中男性3662例,女性3330例,男女之比为1.10∶1。年龄（18～92）岁,平均年龄（40.00±11.34）岁,男女之间年龄差异无统计学意义。超声检出脂肪肝1593例（22.8%）,经性别及年龄调整后沈阳市脂肪肝的患病率为21.2%,男性为18.4%,女性为4.4%,男女之间脂肪肝的患病率差异有统计学意义（χ2=667.88,P〈0.001）。不同职业脂肪肝的患病率经年龄及性别调整后相应为：医护人员为18.6%,银行职员为20.3%,机关干部为17.6%,工人为28.7%,工人组明显高于其他3组,差异有统计学意义。男性患者发病高峰在（30～49）岁（41.4%）,女性患者随着年龄的增长逐渐增长。多元回归分析显示：性别、年龄、体重指数BMI、腰围、收缩压、血脂异常、血尿酸、空腹血糖及职业与脂肪肝相关。结论沈阳市脂肪肝的发病率高于南方城市。工人脂肪肝的患病率显著高于医护人员、银行职员及机关干部。脂肪肝的发病率与性别、年龄、代谢综合征及职业相关。     

骨刺浸剂治疗足跟痛

我科在临床中自拟骨刺浸剂治疗足跟痛，取得良好的疗效。 处方组成：炮穿山甲、制鳖甲、威灵仙、元胡、老陈醋。 功能主治：软坚散结，通络止痛。 使用方法：将炮穿山甲、鳖甲、威灵仙、元胡，四味药按3：2：2：1的比例与适量老陈醋一起放在沙锅内煎熬30min后离火，药温适宜时熏洗足跟部。     

非酒精性脂肪性肝病患者血清瘦素和脂联素与胰岛素抵抗的关系

Objective To investigate the serum leptin and adiponectin levels in nonalcoholic fatty liver disease (NAFLD) patients, and their relationship with insulin resistance. Methods A total of 120 cases were enrolled and divided into two groups: NAFLD group (n = 60) and normal control group (n = 60). The serum levels of leptin and adiponectin were measured by EL1SA. The body mass index (BMI), waist-to-hip ratio (WHR), triglyceride (TG), total cholesterol (Tchol), high-density lipoprotein cholesterol (HDL-C), aspartate aminotransferase (AST), alanine aminotransferase (ALT), gamma-glutamyl transpeptidase (GGT), fasting blood glucose (FBG) and HOMA-IR (homeostasis model assessment insulin resistance) were detected and analyzed. Results Compared with control group, the serum leptin level in NAFLD group was Significantly higher [(12.37 ± 1.99) μg/Lvs (5.20 ± 1.03)μg/L,P<0.01], while the serum adiponectin level was significantly lower [(12.69 ± 2.83) mg/L vs (22.83 ± 4.61) mg/L, P < 0.01]. HOMA-IR was also much higher in NAFLD group than that in control group[(4.86 ± 0.63) vs (1.91 ± 0.41), P < 0.01]. Logistic regression analysis showed that leptin was positively correlated with WHR ( P = 8.175, P < 0.01), HOMA-IR ( P = 0.974, P < 0.01 ), FBG ( β = 0.564, P < 0.01). In contrast, adiponectin inversely associated with HOMA-IR ( β = -0.495, P < 0.01 ) and BMI ( β = -0.314, P < 0.01) respectively. Conclusions The increased serum leptin level and decreased serum adiponectin level in NAFLD patients independently associated with HOMA-IR.     

国内外有关神经病学方面的杂志简介

神经病学属临床医学范畴，包含了对临床神经疾病治疗过程中诸多机制方面的认识与揭示，其研究进展的根本出路体现在对基础研究各个领域重点内容的不断认识及不断的突破。纵观SCI收录的部分神经病学杂志的出版内容，并在此同时介绍了《中国神经再生研究（英文版）》杂志2008年12期的组稿重点，请读者、作者评价这些选题是否和国际的热点研究同步。[第一段]     

178例肝硬化的并发症分析

肝硬化是大多数慢性肝病发展的终末期阶段，患者往往因其并发症的出现病情迅速恶化，甚至死亡。掌握各种常见并发症的特点，寻求有效的防治措施，对改善肝硬化患者的预后有着重要的意义。现对我院2007年1月～2007年10月住院的178例肝硬化患者的并发症进行分析：     

生肌祛白合剂的制备及质量标准

生肌祛白合剂是我院皮肤科医师多年从事临床的经验方,用于治疗白癜风,疗效满意.现将制备方法及质量标准报道如下. 1.方药组成及制备工艺 处方:白蒺藜、墨旱莲、重楼、白药子、白薇、红花、炒桃仁、龙胆草、海螵蛸、制苍术、制何首乌、降香、甘草.