糖尿病性动眼神经麻痹及其中医治疗

糖尿病性动眼神经麻痹较为常见,临床大多使用小剂量糖皮质激素以改善微循环、营养神经药物对患者进行治疗,但服药时间较长、疗效较差,而且很可能因为使用激素引发血糖升高。中医采用中药和针灸治疗糖尿病性动眼神经麻痹,能调节患者脏腑功能、运行气血、平衡阴阳,达到恢复眼神经功能的目的,疗效确切,且无明显不良反应。     

Effect of Chinese Herbal Medicines for Nourishing Yin, Supplementing Qi, and Activating Blood on Reproductive Endocrine Activity and Immune Functions in Patients with Primary Sjogren's Syndrome

Objective:To investigate the effect of Chinese herbal medicines for nourishing yin,supplementing qi,and activating blood on the reproductive endocrine-immune network and its mechanisms in patients with primary Sjogren's syndrome(pSS).Methods:Seventy pSS patients were randomly assigned to two groups using a randomized digital table:the integrative therapy group(36 cases) and the control group(34 cases).Thirty healthy subjects were taken as a normal group.The control group was treated with hydroxychloroquine sulfate tablets alone,and the integrative therapy group was treated by Chinese herbal medicines for nourishing yin,supplementing qi,and activating blood combined with hydroxychloroquine sulfate tablets.The treatment course was 6 months for both groups.Before and after treatment,serum estradiol(E2),testosterone(T),luteinizing hormone(LH),prolactin(PRL) by radioimmunoassay and immunoglobulin(IgG) by immunodiffusion,erythrocyte sedimentation rate(ESR) by Westergren,interferon-γ(IFN-γ) and interleukin-4(IL-4) by enzyme linked immunosorbent assay were determined.Results:E2 and T levels in all patients were lower than those of normal subjects before treatment(P0.05) and were increased significantly after 6-month treatment(P0.05).ESR,FSH,LH,IgG,IFN-γ,IL- 4 and ratios of E2/T,and IFN- 7/IL in the patients were higher than those of normal subjects before the treatments(P0.05),and were reduced significantly after the treatments(P0.05).The T and IFN-γ levels and E2/T ratio in the patients treated with integrative therapy were reduced significantly compared with the control group(P0.05).However,the PRL levels before and after treatment were not significantly changed in the two groups(P0.05).The ratios of E2/T and IFN-γ/IL-4,and levels of IgG and ESR were positively correlated before and after treatment(P0.05).Conclusions:The ratios of E2/T and IFN- γ /IL-4 might be used as indicators of pSS activity.Chinese herbal medicines for nourishing yin,supplementing qi,and activating blood combined with Western medicine could improve the therapeutic effect by regulating the reproductive endocrine-immune network in pSS patients.     

温病“毒”之病因和病机及治疗方法

对温病学"毒"的概念、病因、病机及治疗方法等方面进行探讨,在温病学中"毒"既是病因又是病机概念。毒有火热秽浊的特性,致病性强,有特异性。毒主要通过致热、伤津耗气、瘀血动血腐肉等导致温病的发生发展和变化。治疗毒邪的方法有清热、泄热、开郁、化瘀、扶正,以消除病理产物、减轻毒势、调理气血阴阳等。