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1.
Even if a ceramic's homogenized properties (such as anisotropically evolving stiffness) truly can be predicted from complete knowledge of sub-continuum morphology (e.g., locations, sizes, shapes, orientations, and roughness of trillions of crystals, dislocations, impurities, pores, inclusions, and/or cracks), the necessary calculations are untenably hypervariate. Non-productive (almost derailing) debates over shortcomings of various first-principles ceramics theories are avoided in this work by discussing numerical coarsening in the context of a pedagogically appealing buckling foundation model that requires only sophomore-level understanding of springs, buckling hinges, dashpots, etc. Bypassing pre-requisites in constitutive modeling, this work aims to help students to understand the difference between damage and plasticity while also gaining experience in Monte-Carlo numerical optimization via scale-bridging that reduces memory and processor burden by orders of magnitude while accurately preserving aleatory (finite-sampling) perturbations that are crucial to accurately predict bifurcations, such as ceramic fragmentation.  相似文献   
2.
Phorbol 12-myristate 13-acetate (PMA) is a potent tumor promoter and highly inflammatory in nature. Here, we investigated the toxic effects of PMA on different model system. PMA (10 μg) caused chromosomal aberrations on the Allium cepa root tip and induced mitotic dysfunction. Similarly, PMA caused embryonic and larval deformities and a plummeted survivability rate on zebrafish embryo in a dose-dependent manner. Persistently, PMA treatment on immortalized human keratinocyte human keratinocyte (HaCaT) cells caused massive inflammatory rush at 4 h and a drop in cell survivability at 24 h. Concomitantly, we replicated a cutaneous inflammation similar to human psoriasis induced by PMA. Herein, we used tangeretin (TAN), as an antagonist to counteract the inflammatory response. Results from an in vivo experiment indicated that TAN (10 and 30 mg/kg) significantly inhibited PMA stimulated epidermal hyperplasia and intra-epidermal neutrophilic abscesses. In addition, its treatment effectively neutralized PMA induced elevated reactive oxygen species (ROS) generation on in vitro and in vivo systems, promoting antioxidant response. The association of hypoxia-inducible factor 1-alpha (HIF-1α)-nuclear factor kappa-light-chain-enhancer of activated b cells (NF-κB) crosstalk triggered by PMA enhanced PKCα-ERK1/2-NF-κB pathway; its activation was also significantly counteracted after TAN treatment. Conclusively, we demonstrated TAN inhibited the nuclear translocation of HIF-1α and NF-κB p65. Collectively, TAN treatment ameliorated PMA incited malignant inflammatory response by remodeling the cutaneous microenvironment.  相似文献   
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Electrophoretic deposition (EPD) of 8 mol% yttria‐stabilized zirconia (YSZ) electrolyte thin film has been carried out onto nonconducting porous NiO‐YSZ cermet anode substrate using a fugitive and electrically conducting polymer interlayer for solid oxide fuel cell (SOFC) application. Such polymer interlayer burnt out during the high‐temperature sintering process (1400°C for 6 h) leaving behind a well adhered, dense, and uniform ceramic YSZ electrolyte film on the top of the porous anode substrate. The EPD kinetics have been studied in depth. It is found that homogeneous and uniform film could be obtained onto the polymer‐coated substrate at an applied voltage of 15 V for 1 min. After the half‐cell (anode + electrolyte) is co‐fired at 1400°C, a suitable cathode composition (La0.65Sr0.3MnO3) thick film paste is screen printed on the top of the sintered YSZ electrolyte. A second stage of sintering of such cathode thick film at 1100°C for 2 h finally yield a single cell SOFC. Such single cell produced a power output of 0.91 W/cm2 at 0.7 V when measured at 800°C using hydrogen and oxygen as fuel and oxidant, respectively.  相似文献   
5.
We present in this paper a new energy-efficient communication scheme called CNS (Compression with Null Symbol) that combines the power of data compression and communication through silent symbol. The concept of communication through silent symbol is borrowed from the energy efficient schemes proposed in Sinha (Proceedings of 6th IEEE consumer communications and networking conference (CCNC), Las Vegas, pp. 1–5, 2009), Ghosh et al. (Proceedings of 27th IEEE international performance computing and communications conference (IPCCC), USA, pp. 85–92, 2008), and Sinha and Sinha (Proceedings of international conference on distributed computing and internet technologies (ICDCIT), LNCS, pp. 139–144, 2008). We show that the average theoretical energy saving at the transmitter by CNS is 62.5%, assuming an ideal channel and for equal likelihood of all possible binary strings of a given length. Next, we propose a transceiver design that uses a hybrid modulation scheme utilizing FSK and ASK so as to keep the cost/complexity of the radio devices low. Considering an additive white gaussian noise (AWGN) channel and a non-coherent detection based receiver, CNS shows a saving in transmitter energy by 30% when compared to binary FSK, for equal likelihood of all possible binary strings of a given length. Simultaneously, there is a saving of 50% at the receiver for all types of data modulation due to halving of the transmitted data duration, compared to binary encoding. In contrast, RBNSiZeComm proposed in Sinha (Proceedings of 6th IEEE consumer communications and networking conference (CCNC), Las Vegas, pp. 1–5, 2009), TSS proposed in Ghosh et al. (Proceedings of 27th IEEE international performance computing and communications conference (IPCCC), USA, pp. 85–92, 2008) and RZE proposed in Sinha and Sinha (Proceedings of international conference on distributed computing and internet technologies (ICDCIT), LNCS, pp. 139–144, 2008) generate average transmitter energy savings of about 41, 20, and 35.2%, respectively. Also, at the receiver side, while RBNSiZeComm does not generate any saving, TSS and RZE produce about 36.9 and 12.5% savings on an average, respectively. Considering certain data types that may occur in the context of some wireless sensor networks (WSN) based applications (e.g., remote healthcare, agricultural WSNs, etc.), our simulation results demonstrate that for AWGN noisy channels, the transmitter side savings vary from about 33–50% on an average, while for RBNSiZeComm, this saving is about 33–61% on the same data set (Sinha in Proceedings of 6th IEEE consumer communications and networking conference (CCNC), Las Vegas, pp. 1–5, 2009). Thus, taking into account the low cost/complexity of the proposed transceiver, these results clearly establish that CNS can be a suitable candidate for communication in low power wireless sensor networks, such as in remote healthcare applications, body area networks, home automation, WSNs for agriculture and many others.  相似文献   
6.
The present work is concerned with the development of a robust reconstruction algorithm for applications involving tomography. In an earlier study it was shown that among the ART family of algorithms, the multiplicative algebraic reconstruction algorithm (MART) was the most appropriate for tomographic reconstruction [1]. In the present work, the MART algorithm has been extended so that (a) its performance is now acceptable over a wider range of relaxation factors, (b) the time requirement for convergence to a solution is lower, and (c) its performance is less sensitive to noise in the projection data. Applications considered for evaluating the proposed algorithms are (1) a circular region with holes, (2) a three-dimensional temperature field in a differentially heated fluid layer, and (3) experimental data recorded in a differentially heated fluid layer using an interferometer. The proposed algorithms are seen to be an improvement over those presently available, for all three examples considered.  相似文献   
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Incorporation of silica into styrene butadiene rubber (SBR)–reclaim rubber (RR) blend system was carried out by sol–gel technique and conventional method. A well known silica coupling agent bis(3‐triethoxysilyl propyl) tetrasulfide was found to affect the curing characteristics and mechanical properties of SBR/RR vulcanizate. Here, the effect of RR on silica reinforcement was studied for different SBR/RR blend system. Silica incorporation by conventional mechanical mixing in absence of TESPT showed a much higher tensile properties than that of silica incorporated by the in situ sol–gel reaction of tetraethoxy silane both in presence and absence of TESPT. Studies of equilibrium swelling in a hydrocarbon solvent were also carried out. ATR study indicates that RR forms bond with silica particles due to the presence of active functional site on RR. The amount of silica incorporated by sol–gel reaction was determined through thermogravimetric analysis (TGA). Scanning electron microscopy (SEM) studies further indicate the coherency and homogeneity in the silica filled SBR/RR vulcanizate. © 2005 Wiley Periodicals, Inc. J Appl Polym Sci 99: 957–968, 2006  相似文献   
9.
In this article, the problem of two Unmanned Aerial Vehicles (UAVs) cooperatively searching an unknown region is addressed. The search region is discretized into hexagonal cells and each cell is assumed to possess an uncertainty value. The UAVs have to cooperatively search these cells taking limited endurance, sensor and communication range constraints into account. Due to limited endurance, the UAVs need to return to the base station for refuelling and also need to select a base station when multiple base stations are present. This article proposes a route planning algorithm that takes endurance time constraints into account and uses game theoretical strategies to reduce the uncertainty. The route planning algorithm selects only those cells that ensure the agent will return to any one of the available bases. A set of paths are formed using these cells which the game theoretical strategies use to select a path that yields maximum uncertainty reduction. We explore non-cooperative Nash, cooperative and security strategies from game theory to enhance the search effectiveness. Monte-Carlo simulations are carried out which show the superiority of the game theoretical strategies over greedy strategy for different look ahead step length paths. Within the game theoretical strategies, non-cooperative Nash and cooperative strategy perform similarly in an ideal case, but Nash strategy performs better than the cooperative strategy when the perceived information is different. We also propose a heuristic based on partitioning of the search space into sectors to reduce computational overhead without performance degradation.  相似文献   
10.
Industry watchers have noted that the success rate of data warehouse (DW) implementations has not been exemplary. It is believed that over 50 percent of DW implementations fail to achieve their stated goals. However, there are things that executives can do to improve their chance of success. Like other forms of organizational change, the DW implementation process follows a three-phased pattern of evolution. Clear recognition by management of the phased logic of DW implementation, and the differing role of critical implementation factors (CIFs) in each of the phases, can enhance the probability of success. This article presents a framework that helps executives visualize how CIFs can be customized and embedded in each phase of the DW implementation process.  相似文献   
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