带筋膜蒂骨瓣移植治疗手舟骨陈旧性骨折疗效观察

我院1998年以来，采用带筋膜蒂骨瓣移植术治疗手舟骨陈旧性骨折47例，效果满意，总结如下。     

不同年龄阶段泛素蛋白在ICR小鼠海马组织表达特征

目的 探讨泛素蛋白水平与年龄的相关性,从而为理解神经变性疾病的年龄相关性提供理论依据.方法 应用特异性泛素抗体采用免疫组织化学方法 检测不同年龄组正常健康ICR小鼠海马CA1区锥体细胞层泛素蛋白的表达及分布特征.结果 海马CA1区锥体细胞层泛素蛋白阳性神经元数目及HE染色神经元数目均随年龄逐渐减少,泛素蛋白阳性区域平均...     

Saitohin基因Q7R多态性与肌萎缩侧索硬化的相关性研究

目的 探讨中国人种Saitohin基因(STH)Q7R多态性与肌萎缩侧索硬化(amyotrophic lateral sclerosis,ALS)的发病相关性.方法 采用病例-对照研究,应用递减聚合酶链式反应-限制性酶切片段长度多态性(Touchdown-PCR-RFLP)方法检测135例ALS患者和135例正常人STH基因Q7R多态性.结果 所有DNA样本的STH基因均为QQ型纯合子.结论 STH基因Q7R多态性与ALS无相关性.     

胫骨平台骨折42例临床分析

胫骨平台骨折是临床常见关节内骨折,因存在不同程度的关节面塌陷和正常轴向对线丧失,最终可导致晚期骨性关节炎,对膝关节的协调性、完整性及稳定性影响较大,经常导致膝关节疼痛、不稳及功能障碍.     

腕管综合征神经卡压：内镜下腕管松解与有限小切口松解的效果及安全性评价

BACKGROUND:Existing evidence has shown endoscopic carpal tunnel release is superior to the open release in postoperative recovery time, grip and pinch strength, hospitalization time as well as incidence of postoperative scar tissues. OBJECTIVE: To systematically review the efficacy and safety of endoscopic release versus mini-open release for carpal tunnel syndrome. METHODS: A computer-based search of PubMed, the Cochrane Library, EMbase, Web of Science, CNKI, CqVip and Wanfang databases was performed. Randomized controlled trials comparing endoscopic release with mini-open release for patients with carpal tunnel syndrome were included, and the publishing time was up to November 1st, 2015. Two authors independently screened, extracted data and assessed the risk of bias of the included literatures. Then statistical analysis was conducted using RevMan 5.3 software. RESULTS AND CONCLUSION: A total of 11 randomized controlled trials involving 706 patients were included. The results of Meta-analysis demonstrated that: compared with mini-open release, endoscopic release could not only significanthy decrease the hospitalization time postoperative recovery time and complications (P < 0.05), but also achieve better symptom relief (P=0.16). However, there were no significant differences in grip and pinch strength between the two treatments. These results suggest that compared with the mini-open release, the endoscopic release contributes to shorter hospitalization time and postoperative recovery time, better symptom relief and lower risk of complications. But large-sample and high-quality randomized controlled trials are needed to provide more reliable evidence for these findings. 中国组织工程研究杂志出版内容重点：组织构建;骨细胞;软骨细胞;细胞培养;成纤维细胞;血管内皮细胞;骨质疏松;组织工程     

颅内表皮样囊肿恶变鳞癌1例报告并文献复习

目的 总结颅内胆脂瘤恶变鳞癌的诊治经验。方法 回顾性分析1例右侧桥小脑区胆脂瘤恶变鳞癌的临床资料,并结合相关文献进行分析。结果 63岁男性,13年前曾行右侧桥小脑角区胆脂瘤切除术。本次手术次全切除肿瘤,术后病理结果示鳞状细胞癌,术后随访发现残余肿瘤增大,拒绝再次手术、放疗及化疗,生存22个月后死亡。结论 颅内表皮样囊肿恶变鳞癌无特异表现,术前诊断较困难,手术切除仍是主要治疗手段,放化疗疗效不确定。     

法舒地尔对于缓解稳定性心绞痛的效果观察及对hs—CRP和FIB的影响

目的探讨法舒地尔对缓解稳定性心绞痛发作以及对血高敏感C-反应蛋白（hs—CRP）及纤维蛋白原（FIB）的影响。方法将76例稳定性心绞痛患者随机分为治疗组（法舒地尔组40例）和常规治疗组（对照组36例）,两组均治疗一个月。治疗组在常规治疗基础上给予法舒地尔治疗。于治疗前和治疗后1个月测定hs—CRP及FIB并进行比较,对心绞痛发作情况进行对比。结果治疗组治疗1个月后hs—CRP／FIB显著降低,与治疗前相比,差异有统计学意义（P〈0．01）,与对照组相比较差异有统计学意义（P〈0．01）。两组患者治疗期间心绞痛发作次数比较,差异无统计学意义（P〉0．05）。结论法舒地尔可以有效减少心肌炎性反应过程,改善凝血活陛,减少心绞痛发作。     

神经外科专培手术技能培养初探

<正>神经外科是一门专业性较强的学科,对医师手术技能的培养要求较高。神经外科手术操作步骤复杂、多样、风险大,操作不当易出现严重不良后果,所以神经外科专科医师培养周期相对较长。当前,我国神经外科专科医师规范化培训（以下简称专培）试点的学制为4年,经过4年的专科培养要达到高年资主治医师的水平。在专培期间,如何培养学员的技能,使其能够胜任神经外科的日常手术,是一项重要课题。     

反复IVF-ET失败患者子宫内膜容受性低的经验举隅

子宫内膜容受性低是影响胚胎种植的关键因素,成为反复体外受精-胚胎移植(IVF-ET)失败的主要原因.导师苏健主任医师在长期临床中发现IVF-ET子宫内膜容受性低患者其病机多以气血亏虚、冲任胞宫失养为本,以肝郁气滞、瘀阻胞脉为标.临床上从肝脾肾论治,提出健脾养血、益脾补肾、疏肝活血之法,与辅助生殖周期基本相符,强调从调经...