针灸在现代医学中所扮演的角色

＂Acupuncture in Modern Medicine＂, first published by INTECH in February, 2013, is co-edited by Dr. Lucy L. Chen, an anesthesiologist and pain medicine specialist at Harvard Medical School, and Dr. Tsung O. Cheng, a cardiologist and Professor of Medicine at George Washington University. This book contains a total of eighteen chapters under four general sections, namely, Acupuncture Research, New Development in Acupuncture, Clinical Acupuncture and Acupuncture Therapy Assessment, and offers readers a comprehensive update of acupuncture practices and researches. This work is intended for physicians, acupuncturists, medical students and other healthcare practitioners. A great number of experienced and renowned acupuncture practitioners, clinicians and researchers from both the private and academic worlds contributed to the contents of this book. Topics discussed in this book provide a unique insight to current status and new trends in acupuncture researches accompanied by comprehensive and analytic reviews by scientists and clinicians on clinical application of acupuncture therapy as well as its latest developments.     

Bridging the traditional chinese medicine pattern classification and biomedical disease diagnosis with systems biology

<正>Being the unique core of traditional Chinese medicine(TCM),pattern classification exerts a direct effect on the efficacy and safety of herbal interventions.In this article,the authors integrated the pattern classification and disease diagnosis with many approaches from systems biology.Integration of pattern classification with biomedical diagnosis by systems biology is not only a new direction of personalized medicine development,but also provides a new drug development model.In the further study,the pattern classifications of major diseases will be the focus of research.     

Complementary and Alternative Medicine:Is It Possible to Be Mainstream?

<正>Complementary and alternative medicine(CAM), also known as non-conventional medicine,is used to refer to a broad set of health care practices(such as he rbal medicine,acuPuncture,yoga,Taichi, Qigong,meditation,manual therapies,homeopathic medicine,etc.)that are not part of a country's own tradition,or not integ rated into its dominant health care system.In fact,CAM iS generally used in most developed countries,especially in North America,     

“Acupuncture Journey to America” — A tale of the marvelous

On November 16,2010,China’s acupuncture was officially added to the list of world intangible cultural heritage of humanity by the 5th United Nations Educational,Scientific and Cultural Organization Intergovernmental Committee for Safeguarding Intangible Cultural Heritage.This declaration indicates that acupuncture,the needle therapy of Chinese medicine(CM),has received worldwide recognition by people from different cultures.As a medical therapy, acupuncture has been used to treat a wide range of medical disorders in more than 160 countries.     

Convergence: The tradition and the modern

Recently,Nature(Vol.480 No.7378_supp ppS81-S121,2011) published a special edition of traditional Asian medicine.The title is derived from traditional Chinese medicine.The topics that this special edition discussed are very comprehensive, embedding the development of traditional medicine tracing from its origin to today’s debate on its modernization,including ways to evaluate its safety, efficacy and its legislation.Some perspectives in the     

创刊寄语

世纪更新,当代中国在社会、经济、科技、文化等各个领域都取得了新的激动人心的成就,这些成就相映生辉.迎着生命科学和信息科学迅速发展的春风,我国中西医结合医学界又一新枝绽开--《实用中西医结合临床》杂志以其崭新的姿态创刊了.这是我国临床医学界的一大喜事和新事,我谨代表中国中西医结合学会,表示最诚挚的祝贺!     

XS0601对猪冠脉球囊损伤后内膜细胞凋亡及bcl-2、p53基因表达的影响

目的观察XS0601(由川芎和赤芍的有效部位组成)对猪冠状动脉球囊损伤后细胞凋亡及相关基因bcl-2、野生型p53表达的影响.方法球囊扩张损伤猪冠状动脉左前降支(LAD)中段内膜的方法建立再狭窄(RS)模型.其中对照组不给予特殊药物治疗,各药物组于术前2天开始给药,持续至术后4周处死.原位杂交方法观察球囊损伤后内膜中bcl-2、p53mRNA表达,原位末端标记法(ISEL)检测内膜中的凋亡细胞,并研究药物对细胞凋亡的影响.结果损伤后4周动脉在内弹力板(IEL)断裂情况下,形成了明显的新生内膜.小剂量和大剂量XS0601均可增加内膜中的凋亡细胞,其凋亡细胞阳性表达面积率与对照组相比差异有显著性(P<0.01和P<0.05);并能减少内膜中的bcl-2阳性杂交颗粒,增加p53阳性杂交颗粒.结论猪冠状动脉球囊损伤后新生内膜中的细胞凋亡水平较低,凋亡抑制基因bcl-2的表达增加.XS0601可通过减少凋亡抑制基因bcl-2的表达,上调凋亡促进基因p53的表达,从而对猪冠状动脉球囊损伤后SMC增殖过程中较低的凋亡水平进行调控,诱导新生内膜中的细胞凋亡.     

再灌注致大鼠心肌线粒体损伤及益心康胶囊的保护作用

目的　观察再灌注对心肌线粒体的损伤 ,评价中药复方———益心康胶囊 (H30 3)的保护作用。方法　利用离体大鼠全心停灌 /再灌 (I/R)模型 ,测定心肌线粒体结构和功能的变化。结果　I/R可致线粒体结构和功能损伤 ,H30 3预先灌注给药可明显减轻心肌脂质过氧化程度 ,抑制磷脂酶A2 活性 ,抑制线粒体磷脂降解和游离脂肪酸生成 ,改善线粒体膜脂流动性。此外对呼吸功能及Ca2 + ATPase活性也具有明显的保护作用。结论　H30 3对再灌注所致的线粒体的损伤具有明显的保护作用     

不同证型失眠患者与健康人群脉图特征参数图谱比较北大核心CSCD

目的比较分析不同证型失眠患者与健康人群之间脉图参数的变化规律,探索特征参数。方法运用智能脉诊仪采集16例火热相关证候失眠患者、18例心脾两虚证失眠患者及20名健康人群的寸口六部脉的脉图参数,应用最小二乘回归选优方法进行分析,使用特征参数图谱方式进行表达。结果失眠心脾两虚证的特征参数包括时域参数2个(左、右尺w),频域参数23个(右尺相位6、左关能量6等),主要分布在左尺、右尺及左关部位;失眠火热证相关的特征参数包括六部脉脉位,时域参数5个(左关h1、左尺h1等),频域参数9个(右关能量4、右尺能量4等),主要分布在右寸、右关和右尺部位;失眠两组之间的特征参数包括时域参数5个(右寸t1、右尺h1等),频域参数7个(右寸相位7、左寸相位12)等。结论不同证型失眠患者与健康人群及失眠不同证型间的脉诊参数存在差异,右尺相位6/左关能量6、右关能量4/右尺能量4及左寸相位12/右寸相位7可能分别为失眠心脾两虚证、火热证及心脾两虚证火热证的特征指标。