广东生物医药企业竞争态势及高等医药院校图书馆参与竞争情报服务的探讨

介绍竞争情报含义、主要功能,从优势、劣势、机遇、挑战4个方面具体分析广东生物医药企业现状,并对高等医药院校图书馆参与医药企业竞争情报服务的优势以及主要方式进行探讨     

Consumer Resources for Cancer on the World-Wide Web

Abstract

There is now a staggering amount of consumer health information relating to cancer available and accessible on the World-Wide Web (WWW or Web). The sheer quantity of information can sometimes make it difficult to locate the best sites for one's needs. The purpose of this article is to point out some of the more useful sites for obtaining cancer information and to highlight their special features. The WWW cancer resources are grouped into five sections: I. Major Sites; II. Sites for Specific Types of Cancer; III. Other Useful Sites; IV. Guides; and V. Collections.     

Application of combinatorial chemistry to antimicrobial drug discovery

The emergence of pathogens resistant to currently available treatments is seen as a public health crisis. Since few new classes of antimicrobial drugs have been developed in the last two decades, it is becoming increasingly probable that healthcare providers will be faced with infections for which no chemotherapeutic agent is available. A renewed emphasis is being placed on employing the most advanced drug discovery technologies in the development of new antimicrobials. The recently introduced technologies of combinatorial chemistry offer new sources of chemical diversity, as well as methods with which to produce and rapidly test them. In the last few years, many groups have adopted a number of approaches in order to apply combinatorial chemistry to antimicrobial drug discovery. These combinatorial strategies, and the manner in which they are used to develop new screening formats or to identify new chemical leads are, reviewed.     

高校图书馆随书光盘管理探析

分析随书光盘的特点,介绍高校图书馆随书光盘的几种管理模式,对如何科学管理随书光盘提出几点建议,具体包括合理利用存储空间、引进智能光盘管理库、为随书光盘镜像服务器建立云存储架构等方面。     

医院图书馆嵌入式学科服务模式探析

嵌入式服务是医院图书馆学科服务的新方向,对医院图书馆的发展有着重要意义。介绍嵌入式服务理念、模式和对馆员的需求,阐述医院图书馆嵌入式服务的途径,包括嵌入参考咨询、嵌入临床疾病诊治、嵌入临床课题研究、嵌入临床教学,分析存在的问题和对策。     

Time-resolved fluorometric assay for the detection of endostatin in chromatographically separated extracts of natural peptides

We present a heterogeneous non-competitive immunological detection assay for peptide and protein antigens from crude extracts of biological sources. This time-resolved fluoroimmunoassay (TR-FIA) has been designed in a solid-phase mode using 96-well microtiter plates. Using the rare-earth metal europium as a fluorescent marker, a highly sensitive, selective and efficient procedure was developed. This technique prevents from interferences of intrinsic protein fluorescence which is highly important for antigen measurement in complex matrices. The TR-FIA has been applied for the detection of circulating forms of the potential anti-tumor agent endostatin, a C-terminal fragment of collagen XVIII, and its close homolog collagen XV (restin) from hemofiltrate. Endostatin was detected with a limit of detection of 3 ng (150 fmol/well) and a broad dynamic range from 10-1000 ng/well.     

Our Path to a Filmless Future

Film-based radiographs are still being used to teach in a conference format, which presents several viewing challenges amongst other problems. In the age of cloud computing, which enables the use of online server storage space, this information could be used more effectively if it were digitized. However, digitizing film-based radiographs and making them available for use in the cloud is not as easy as it seems. In order to address the issue of digitizing the film-based radiograph libraries in our radiology department, we looked at several options. The option that we chose was a consumer-grade scanner, and this decision was based on price, resolution, shades of gray, built-in transparency function, and its physical attributes. Our goal was to digitize the film-based radiograph teaching files so they could be stored in a digital file locker such as Google Picassa for organization and quick access later. These files would constantly be updated in a Google document by residents, and this document would be called the “Living Document” based on its continuous expandability. This method would allow even the smallest radiology department to benefit from the use of modern technology to gain access to valuable information stored in film-based radiographs and give every resident the opportunity to benefit from it.     

医院图书馆人力资源管理模式

医院图书馆现代化发展最关键、最重要的因素是人力资源.优化人力资源模式是建设高素质人才队伍的有效途径,这对于医院图书馆事业的全面发展具有关键性作用.通过对结构优化的基本目标和主要措施的讨论,探讨了优化医院图书馆人力资源管理模式的途径.     

开展“学科馆员”工作的体会

介绍了作者从事"学科馆员"工作的经验与体会,对高校图书馆开展深层次文献信息服务的方式进行了探讨.