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31.
Kexin Jiao Laurence J. Walsh Sao Ivanovski Pingping Han 《International journal of molecular sciences》2021,22(9)
Periodontitis is a chronic complex inflammatory disease associated with a destructive host immune response to microbial dysbiosis, leading to irreversible loss of tooth-supporting tissues. Regeneration of functional periodontal soft (periodontal ligament and gingiva) and hard tissue components (cementum and alveolar bone) to replace lost tissues is the ultimate goal of periodontal treatment, but clinically predictable treatments are lacking. Similarly, the identification of biomarkers that can be used to accurately diagnose periodontitis activity is lacking. A relatively novel category of molecules found in oral tissue, circular RNAs (circRNAs) are single-stranded endogenous, long, non-coding RNA molecules, with covalently circular-closed structures without a 5’ cap and a 3’ tail via non-classic backsplicing. Emerging research indicates that circRNAs are tissue and disease-specific expressed and have crucial regulatory functions in various diseases. CircRNAs can function as microRNA or RNA binding sites or can regulate mRNA. In this review, we explore the biogenesis and function of circRNAs in the context of the emerging role of circRNAs in periodontitis pathogenesis and the differentiation of periodontal cells. CircMAP3K11, circCDK8, circCDR1as, circ_0062491, and circ_0095812 are associated with pathological periodontitis tissues. Furthermore, circRNAs are expressed in periodontal cells in a cell-specific manner. They can function as microRNA sponges and can form circRNA–miRNA–mRNA networks during osteogenic differentiation for periodontal-tissue (or dental pulp)-derived progenitor cells. 相似文献
32.
Wireless Networks - Orthogonal frequency-division multiplexing with random multiple access (OFDRMA) is discussed for down-link communications, whereby a single base-station transmits information... 相似文献
33.
Cybernetics and Systems Analysis - The authors propose a method for solving the problem of approach of controlled objects in dynamic game problems with a terminal payoff function. The method is... 相似文献
34.
Kamar M. S. Shalan A. S. Youssef W. M. Hussein A. E. M. Khawassek Y. M. Taha M. H. 《Radiochemistry》2022,64(2):244-256
Radiochemistry - Ferrugination, sericitization, desulfitization, chloritization, and kaolinitization of hydrothermal origin are the main wall rock alterations occurring within the NNW shear zones... 相似文献
35.
肝损伤(liver injury)是指基因遗传或外部原因诱发的肝脏功能异常性疾病.临床表现为食欲不振、乏力、恶心、黄疸、疲乏等,严重者将出现肝功能衰竭,致死风险极高.在交通肇事、暴力犯罪及意外事件中,肝由于体积大、位置固定、质地脆弱、血运丰富等原因,往往是最容易发生损伤的器官之一,肝损伤后的死亡率可高达10.5%~25%[1].随着时间的变化,肝损伤的程度、病理改变、GM-CSF等相关细胞因子及CBS等相关酶的表达水平也会进一步变化.肝损伤后,由于肝内部环境稳态的破坏,器官的状态、结构、各种蛋白的转录水平、蛋白及细胞因子的表达变化水平也会发生一定程度的改变.因此定性定量地分析这些变化,找到时间相关性强的特异性指标,对于指导法医学的实践具有重要的作用.因此在法医学鉴定中,通过肝脏损伤及病变程度的改变,明确肝损伤病变与死亡时间的关系有利于判断事件或案件性质,并有助于进一步对责任方的认定. 相似文献
36.
Ib Holzmeister Jan Weichhold Jürgen Groll Hala Zreiqat Uwe Gbureck 《Journal of the American Ceramic Society》2021,104(7):3554-3561
In this study, the hydraulic reactivity and cement formation of baghdadite (Ca3ZrSi2O9) was investigated. The material was synthesized by sintering a mixture of CaCO3, SiO2, and ZrO2 and then mechanically activated using a planetary mill. This leads to a decrease in particle and crystallite size and a partial amorphization of baghdadite as shown by X-ray powder diffraction (XRD) and laser diffraction measurements. Baghdadite cements were formed by the addition of water at a powder to liquid ratio of 2.0 g/ml. Maximum compressive strengths were found to be ~2 MPa after 3-day setting for a 24-h ground material. Inductively coupled plasma mass spectrometry (ICP-MS) measurements showed an incongruent dissolution profile of set cements with a preferred dissolution of calcium and only marginal release of zirconium ions. Cement formation occurs under alkaline conditions, whereas the unground raw powder leads to a pH of 11.9 during setting, while prolonged grinding increased pH values to approximately 12.3. 相似文献
37.
Romero-Garcés A. Salles De Freitas R. Marfil R. Vicente-Chicote C. Martínez J. Inglés-Romero J. F. Bandera A. 《Multimedia Tools and Applications》2022,81(3):3603-3628
Multimedia Tools and Applications - The design of robots capable of operating autonomously in changing and unstructured environments, requires using complex software architectures in which,... 相似文献
38.
Huang Samuel Cleaveland Rance 《International Journal on Software Tools for Technology Transfer (STTT)》2022,24(3):473-492
International Journal on Software Tools for Technology Transfer - This paper describes a technique for solving temporal-logic queries over finite sets of finite-length data streams. Such data... 相似文献
39.
Yu-Xuan Li Ping Li Yu-Zhe Wu Zhen-Liang Xu Ming-Ling Huang 《Ceramics International》2021,47(2):2180-2186
A novel TiO2 thin film was prepared on the ceramic hollow fiber by the sol-gel method using poly(vinylpyrrolidone) (PVP) and polyvinyl alcohol (PVA) as additives. SEM images verified the formation of TiO2 layer with various thickness using different composition of titania sols. The effect of the PVP and PVA contents on the TiO2 sol properties, the separation and the antifouling performance of the ultrafiltration membranes were investigated thoroughly. When the contents of PVP and PVA were 1.0 wt% and 0.8 wt%, respectively, the resultant membrane showed a thickness of 0.55 μm with a pure water flux of 255 L m?2 h?1. In addition, the adherent foulant bovine serum albumin was applied to evaluate the antifouling performance. During the three fouling-recovery cycles, the flux recovery ratio and the flux decay ratio maintained about 99% and 30%. The BSA flux and rejection were still 169 L m?2 h?1 and 96.9% after the cycles, indicating a superior antifouling property. 相似文献
40.
Belcher Calvin H. Zheng Baolong MacDonald Benjamin E. Langlois Eric D. Lehman Benjamin Pearce Charles Delaney Robert Apelian Diran Lavernia Enrique J. Monson Todd C. 《Journal of Materials Science》2022,57(9):5518-5532
Journal of Materials Science - For transformers and inductors to meet the world’s growing demand for electrical power, more efficient soft magnetic materials with high saturation magnetic... 相似文献