Right–left digit ratio (2D:4D) predicts free testosterone levels associated with a physical challenge

Abstract

There is evidence that the digit ratio (2D:4D) is a negative correlate of prenatal levels of testosterone, but there is no association between 2D:4D and the circulating levels of both total and free testosterone. Sports provide a physical challenge and participants often show increased levels of free testosterone immediately preceding and during competition. We tested this hypothesis of a link between 2D:4D and testosterone under challenge in 79 professional rugby players using the following procedures; (i) 25 players were physically challenged using a repeated sprint agility test, and saliva samples were assayed for testosterone immediately preceding the repeated sprint agility test (time 1) and 5 minutes (time 2) and 20 minutes after completion of the repeated sprint ability (time 3); (ii) 54 players were also tested for salivary testosterone in an unchallenged condition. We found that right-left 2D:4D was significantly and negatively related to testosterone concentrations at times 1, 2 and 3 following the repeated sprint agility test (P < 0.05) and there was no association between the 2D:4D and basal testosterone levels in the unchallenged group. We suggest that low right–left 2D:4D is a predictive marker of free testosterone responsiveness when trained men are physically challenged, and that this association is programmed by the action of prenatal testosterone.     

Digit ratio (2D:4D) and performance in elite rugby players

The relative length of the second and fourth digits (2D:4D) is a putative marker for prenatal testosterone. Low 2D:4D has been reported to correlate with high performance in sport in general. Here, for the first time, we examine the relationship between 2D:4D and performance in elite rugby players. The 44 players (28 forwards, 16 backs) were drawn from the Ospreys Rugby Union Club and 44 age-matched controls. The measures of performance comprised age-adjusted number of international performances (caps) for Wales, a comparison of coaches' first-choice League team with others, and the number of tries scored by backs in club matches. Compared with controls, players were larger and had lower 2D:4D for the right and left hand. With regard to number of caps, players with low 2D:4D in their right hand and low right 2D:4D compared with their left (right?-?left 2D:4D difference) had high numbers of caps. First-choice players did not differ significantly from second-choice players in their 2D:4D but they did have a lower right?-?left 2D:4D difference than second-choice players. Low right 2D:4D and low right?-?left 2D:4D difference were significantly linked with large numbers of tries. We conclude that low right 2D:4D and low right?-?left 2D:4D difference are predictors of high rugby performance.     

Digit ratio (2D:4D) and performance in elite rugby players

Abstract

The relative length of the second and fourth digits (2D:4D) is a putative marker for prenatal testosterone. Low 2D:4D has been reported to correlate with high performance in sport in general. Here, for the first time, we examine the relationship between 2D:4D and performance in elite rugby players. The 44 players (28 forwards, 16 backs) were drawn from the Ospreys Rugby Union Club and 44 age-matched controls. The measures of performance comprised age-adjusted number of international performances (caps) for Wales, a comparison of coaches' first-choice League team with others, and the number of tries scored by backs in club matches. Compared with controls, players were larger and had lower 2D:4D for the right and left hand. With regard to number of caps, players with low 2D:4D in their right hand and low right 2D:4D compared with their left (right ? left 2D:4D difference) had high numbers of caps. First-choice players did not differ significantly from second-choice players in their 2D:4D but they did have a lower right ? left 2D:4D difference than second-choice players. Low right 2D:4D and low right ? left 2D:4D difference were significantly linked with large numbers of tries. We conclude that low right 2D:4D and low right ? left 2D:4D difference are predictors of high rugby performance.     

有氧耐力的测试指标和训练方法研究新进展

有氧耐力是人体从事耐力性运动的重要能力一，最大摄氧量是客观评价人体心肺功能的一项综合生理指标。本文对有氧耐力的重要测试指标最大摄氧量和无氧阈在有氧耐力评价中的作用及其影响因素进行了综合分析，并梳理了有氧耐力训练的新方法。耐力性项目的连动成绩与最大摄氧量关系紧密，而无氧阀在评定有氧耐力水平、制订有氧耐力训练强度等许多方面亦具有较强的指导意义。有氧耐力训练在很多项目训练中占有重要地位，掌握科学的有氧耐力训练方法对提高运动员的专项竞技水平起着关键性作用。     

极限负荷时β-内啡肽、睾酮、皮质醇对心肺功能的影响

极限负荷时运动持续时间和运动水平密切相关。研究发现运动后睾酮（T）水平与耗氧平台（VO2maxPD）显著相关,β－内啡肽（β－EP）分泌水平与最大耗氧量,耗氧平台,呼吸频率显著相关。揭示耗氧平台的维系,可能有垂体—性腺轴的参与。而β－内啡肽对呼吸频率及耗氧平台的维系也存在着调控作用。耗氧平台时心率和通气量较之安静时大辐度增长,间接说明儿茶酚胺在极限负荷时对循环系统的支持。     

Relationship between maximal oxygen uptake and oxygen uptake attained during treadmill middle-distance running

Traditionally, it has been assumed that during middle-distance running oxygen uptake (VO2) reaches its maximal value (VO2max) providing the event is of a sufficient duration; however, this assumption is largely based on observations in individuals with a relatively low VO2max. The aim of this study was to determine whether VO2max is related to the VO2 attained (i.e. VO2peak) during middle-distance running on a treadmill. Fifteen well-trained male runners (age 23.3 +/- 3.8 years, height 1.80 +/- 0.10 m, body mass 76.9 +/- 10.6 kg) volunteered to participate in the study. The participants undertook two 800-m trials to examine the reproducibility of the VO2 response. These two trials, together with a progressive test to determine VO2max, were completed in a randomized order. Oxygen uptake was determined throughout each test using 15-s Douglas bag collections. Following the application of a 30-s rolling average, the highest VO2 during the progressive test (i.e. VO2max) was compared with the highest VO2 during the 800-m trials (i.e. VO2peak) to examine the relationship between VO2max and the VO2 attained in the 800-m trials. For the 15 runners, VO2max was 58.9 +/- 7.1 ml x kg(-1) x min(-1). Two groups were formed using a median split based on VO2max. For the high and low VO2max groups, VO2max was 65.7 +/- 3.0 and 52.4 +/- 1.8 ml x kg(-1) x min(-1) respectively. The limits of agreement (95%) for test-retest reproducibility for the VO2 attained during the 800-m trials were +/- 3.5 ml x kg(-1) x min(-1) for a VO2peak of 50.6 ml x kg(-1) x min(-1) (the mean VO2peak for the low VO2max group) and +/- 2.3 ml x kg(-1) x min(-1) for a VO2peak of 59.0 ml x kg(-1) x min(-1) (the mean VO2peak for the high VO2max group), with a bias in VO2peak between the 800-m runs (i.e. the mean difference) of 1.2 ml x kg(-1) x min(-1). The VO2peak for the 800-m runs was 54.8 +/- 4.9 ml x kg(-1) x min(-1) for all 15 runners. For the high and low VO2max groups, VO2peak was 59.0 +/- 3.3 ml x kg(-1) x min(-1) (i.e. 90% VO2max) and 50.6 +/- 2.0 ml x kg(-1) x min(-1) (i.e. 97% VO2max) respectively. The negative relationship (-0.77) between VO2max and % VO2max attained for all 15 runners was significant (P = 0.001). These results demonstrate that (i) reproducibility is good and (ii) that VO2max is related to the %VO2max achieved, with participants with a higher VO2max achieving a lower %VO2max in an 800-m trial on a treadmill.     

Endurance running performance in athletes with asthma

Laboratory assessment was made during maximal and submaximal exercise on 16 endurance trained male runners with asthma (aged 35 +/- 9 years) (mean +/- S.D.). Eleven of these asthmatic athletes had recent performance times over a half-marathon, which were examined in light of the results from the laboratory tests. The maximum oxygen uptake (VO2max) of the group was 61.8 +/- 6.3 ml kg-1 min-1 and the maximum ventilation (VEmax) was 138.7 +/- 24.7 l min-1. These maximum cardio-respiratory responses to exercise were positively correlated to the degree of airflow obstruction, defined as the forced expiratory volume in 1 s (expressed as a percentage of predicted normal). The half-marathon performance times of 11 of the athletes ranged from those of recreational to elite runners (82.4 +/- 8.8 min, range 69-94). Race pace was correlated with VO2max (r = 0.863, P less than 0.01) but the highest correlation was with the running velocity at a blood lactate concentration of 2 mmol l-1 (r = 0.971, P less than 0.01). The asthmatic athletes utilized 82 +/- 4% VO2max during the half-marathon, which was correlated with the %VO2max at 2 mmol l-1 blood lactate (r = 0.817, P less than 0.01). The results of this study suggest that athletes with mild to moderate asthma can possess high VO2max values and can develop a high degree of endurance fitness, as defined by their ability to sustain a high percentage of VO2max over an endurance race. In athletes with more severe airflow obstruction, the maximum ventilation rate may be reduced and so VO2max may be impaired. The athletes in the present study have adapted to this limitation by being able to sustain a higher %VO2max before the accumulation of blood lactate, which is an advantage during an endurance race. Therefore, with appropriate training and medication, asthmatics can successfully participate in endurance running at a competitive level.     

Determinants of success during triathlon competition

Eleven male triathletes were studied to determine the relationships between selected metabolic measurements and triathlon performance. Measurements of oxygen uptake (VO2), pulmonary ventilation (VE), and heart rate (HR) were made during submaximal and maximal 365.8 m freestyle swimming (FS), cycle ergometry (CE), and treadmill running (TR). Submaximal workloads were 1 m/s for swimming, 200 W for cycling, and 201.2 m/min for running. The mean VO2 max (l/min) was significantly (p less than .05) lower during FS (4.17) than CE (4.68) or TR (4.81). Swimming, cycling, and running performance times during the Muncie Endurathon (1.2 mile swim, 56 mile cycle, 13.1 mile run) were not significantly related to the event-specific VO2 max (ml/kg/min): -.49, -32 and -.55, respectively. The VO2 max expressed in l/min was found to be significantly (p less than .05) related to cycling time (r = -.70). A significant (p less than .05) relationship was observed between submaximal VO2 (ml/kg/min) during TM and run performance time (r = .64), whereas swimming and cycling performance times were significantly (p less than .05) related to submaximal VO2 max (l/min), r = .72 and .60, respectively. The percentage of VO2 (%VO2 max) used during the submaximal tests was significantly (p less than .05) related to swimming (.91), cycling (.78), and running (.86) performance times. Time spent running and cycling during triathlon competition was significantly (p less than .05) related to overall triathlon time, r = .97 and .81, respectively. However, swimming time was not significantly related (.30) to overall triathlon time. This study suggests that economy of effort is an important determinant of triathlon performance.     

Prenatal programming of sporting success: Associations of digit ratio (2D:4D), a putative marker for prenatal androgen action,with world rankings in female fencers

Abstract

Associations of the second-to-fourth digit ratio (2D:4D), a putative marker for prenatal androgen action, and of absolute finger length, a putative marker for pubertal–adolescent androgen action, with sport performance were examined in a multinational sample of 87 world-class women épée fencers. Lower (masculinized) digit ratios correlated, although not significantly so, with better current and highest past world rankings. These correlations were significant for right-hand 2D:4D with controls for the most salient factors for 2D:4D (ethnicity) and world rankings (years of international experience, height, and weight). Longer (masculinized) fingers correlated strongly with better current and highest past world rankings; these correlations became insignificant with the same controls. Replicating previous evidence for fencers, left-handedness was much more prevalent in this sample (21%) than in the female general population, and left-handers had somewhat, but not significantly so, lower 2D:4D as well as better world rankings than right-handers. These findings extend related evidence suggestive of prenatal programming of aptitude across a variety of sports, especially running and soccer. Some known extragenital effects of prenatal testosterone that contribute to the development of efficient cardiovascular systems, good visuospatial abilities, physical endurance and speed, and to the propensity for rough-and-tumble play, apparently promote sporting success in adult life.     

Peak treadmill running velocity during the VO2 max test predicts running performance

Twenty specialist marathon runners and 23 specialist ultra-marathon runners underwent maximal exercise testing to determine the relative value of maximum oxygen consumption (VO2max), peak treadmill running velocity, running velocity at the lactate turnpoint, VO2 at 16 km h-1, % VO2max at 16 km h-1, and running time in other races, for predicting performance in races of 10-90 km. Race time at 10 or 21.1 km was the best predictor of performance at 42.2 km in specialist marathon runners and at 42.2 and 90 km in specialist ultra-marathon runners (r = 0.91-0.97). Peak treadmill running velocity was the best laboratory-measured predictor of performance (r = -0.88(-)-0.94) at all distances in ultra-marathon specialists and at all distances except 42.2 km in marathon specialists. Other predictive variables were running velocity at the lactate turnpoint (r = -0.80(-)-0.92); % VO2max at 16 km h-1 (r = 0.76-0.90) and VO2max (r = 0.55(-)-0.86). Peak blood lactate concentrations (r = 0.68-0.71) and VO2 at 16 km h-1 (r = 0.10-0.61) were less good predictors. These data indicate: (i) that in groups of trained long distance runners, the physiological factors that determine success in races of 10-90 km are the same; thus there may not be variables that predict success uniquely in either 10 km, marathon or ultra-marathon runners, and (ii) that peak treadmill running velocity is at least as good a predictor of running performance as is the lactate turnpoint. Factors that determine the peak treadmill running velocity are not known but are not likely to be related to maximum rates of muscle oxygen utilization.     

mtDNA D-loop 多态性与澳大利亚自行车运动员有氧运动能力关系初探

研究目的:探讨了mtDNA D-loop多态性与澳大利亚自行车运动员的VO2max及优异耐力成绩的关系.研究结果:前期研究发现虽然运动员组和对照组VO2max有显著性差异,但mtDNA D-loop的多态性在两组的分布频率没有显著性差异.     

mtDNA D-loop多态性与澳大利亚自行车运动员有氧运动能力关系初探(英文)

研究目的 :探讨了 mt DNA D- loop多态性与澳大利亚自行车运动员的 VO2 max及优异耐力成绩的关系。研究结果 :前期研究发现虽然运动员组和对照组 VO2 max有显著性差异 ,但 mt DNA D- loop的多态性在两组的分布频率没有显著性差异     

Physical activity,physiological, and psychomotor performance: a study of variously active older adult men

This research examined varying levels of physical activity and psychomotor and physiological function in variously active older men. Very active moderately active, and low active participants were tested on simple (SRT) and choice reaction time (CRT), coincidence-anticipation timing (CAT), and VO2max. No significant differences for age or height were found, although percentage of fat, and weight were statistically different. Active groups were leaner and lighter. VO2max was significantly different between groups, as physically active groups yielded geater values. SRT and CAT also yielded significantly different results with more active participants showing better performance. No between-groups significant differences resulted for CRT. Generally, increased levels of physical activity were related to superior physiological outcomes and improved psychomotor peformance.     

The relationship between selected physiological variables of rowers and rowing performance as determined by a 2000 m ergometer test

The aim of this study was to establish the relationship between selected physiological variables of rowers and rowing performance as determined by a 2000 m time-trial on a Concept II Model B rowing ergometer. The participants were 13 male club standard oarsmen. Their mean (+/- s) age, body mass and height were 19.9+/-0.6 years, 73.1+/-6.6 kg and 180.5+/-4.6 cm respectively. The participants were tested on the rowing ergometer to determine their maximal oxygen uptake (VO2max), rowing economy, predicted velocity at VO2max, velocity and VO2 at the lactate threshold, and their velocity and VO2 at a blood lactate concentration of 4 mmol x l(-1). Percent body fat was estimated using the skinfold method. The velocity for the 2000 m performance test and the predicted velocities at the lactate threshold, at a blood lactate concentration of 4 mmol x l(-1) and at VO2max were 4.7+/-0.2, 3.9+/-0.2, 4.2+/-0.2 and 4.6+/-0.2 m x s(-1) respectively. A repeated-measures analysis of variance showed that the three predicted velocities were all significantly different from each other (P<0.05). The VO2max and lean body mass showed the highest correlation with the velocity for the 2000 m time-trial (r = 0.85). A stepwise multiple regression showed that VO2max was the best single predictor of the velocity for the 2000 m time-trial; a model incorporating VO2max explained 72% of the variability in 2000 m rowing performance. Our results suggest that rowers should devote time to the improvement of VO2max and lean body mass.     

20-MST监测心肺功能变化的有效性及敏感性研究

目的:探讨20-MST监测普通大学生心肺功能变化的有效性及对运动训练的敏感性。方法:以32名男性大学生(实验组、对照组各16名)为研究对象,对实验组学生进行8周的有氧耐力训练干预,在实验前后分别测定VO2max、20-MST、库博12min跑、台阶试验四项指标,并对检测结果进行分析比较。结果:20-MST在实验前后与VO2max、12min跑成绩高度相关,与台阶指数低度相关;实验后,各指标均有显著增长,20-MST的增量最明显。结论:20-MST是一种间接评价心肺功能、判断训练效果的有效方法,它对评价运动训练引起心肺功能适应性变化的敏感性高于VO2max。     

Relationship of running economy, ventilatory threshold, and maximal oxygen consumption to running performance in high school females

The purpose of the study was to relate three determinants of distance running success, (a) maximal oxygen consumption (VO2max), (b) ventilatory threshold (VT), and (c) running economy (RE), to actual running time in a 5-km race (ART). Twenty-four female runners (M age = 15.9 years) from four high school teams that competed at the Massachusetts All-State 5-km Cross Country Championship Meet and placed 1st, 7th, 19th, and 20th were tested in the laboratory. The mean VO2max of these runners was 61.7 ml.kg-1.min-1, HRmax 201 b.min-1, VEmax 100 L.min-1, and RER 1.10. The VT occurred at 79% of the VO2max, and HR of 184 b.min-1 (92% of HRmax). The velocity at VT (vVT) and velocity at VO2max (vVO2max) was correlated with ART, r(22) = .78 and .77 (p less than .001), respectively. The VO2 at VT and at maximal exercise was correlated with ART by r(22) = -.66 and -.69 (p less than .001), respectively. The VO2 at 215 m.min-1 (8 mph) was poorly related to ART, r(22) = -.05, p greater than .05. It was concluded that either of the derived variables vVT and vVO2max appear to explain significant variation in distance running performance among adolescent female cross country runners.     

模拟“低住高练（LoHi）”对游泳运动员运动能力的影响

目的探讨LoHi训练法对运动员运动能力的影响机制,为LoHi训练法在运动实践中的应用提供理论和实践依据.方法对15名优秀游泳运动员进行2周的LoHi训练,分别于训练前后进行气体代谢、力竭性递增负荷运动能力测试;在训练的整个过程中进行5次专项有氧能力的测试.结果2周LoHi训练后,①男运动员VO2max、VO2max/kg、Vemax和O2-plusemax显著提高(P＜0.05),女运动员无显著性变化(P＞0.05);②力竭性递增负荷运动后,男女运动员运动后的Bla均非常显著的下降(P＜0.01～0.001),男女间无性别差异(P＞0.05);同时运动后Bla的下降率表现为逐渐升高的趋势;③力竭性递增负荷运动中,男运动员Wmax提高了12.7%(P＜0.01),女运动员则提高了6.12%(P＞0.05); Tmax男子提高17.7%(P＜0.05),女子提高7.44%(P＜0.05);④男运动员在2周LoHi训练过程中运动成绩呈升高趋势,Bla呈逐渐下降趋势,训练后7d运动成绩最好,Bla却下降51.9%(P＜0.01);女运动员在训练过程中运动成绩和Bla均呈下降趋势,训练后7d运动成绩最高,18d下降,但Bla均明显低于训练前(P＜0.01).结论两周LoHi训练提高了运动员对负荷的适应能力,特别使运动员的一般有氧能力和专项有氧能力得到明显改善;同时,女运动员对缺氧的适应能力明显低于男子,表现出明显的性别差异.     

Effects of nicotinamide adenine dinucleotide hydride on physical and mental performance

The aim of this study was to assess the effects of nicotinamide adenine dinucleotide hydride (NADH) on maximal oxygen uptake (VO2max), maximal anaerobic running time, and mental performance. Eight men were exposed to a supplement treatment (30 mg NADH as ENACHI tablets per day) and to a placebo treatment, each of 4 weeks' duration, in a balanced, double-blind, and cross-over design. The two treatments were separated by a 14-week wash-out period. The results indicated that VO2max, maximal anaerobic running time, and the ability to concentrate were similar in the NADH and placebo conditions. There were also no differences in blood lactate, creatine kinase, reaction time or feelings of fatigue between the treatments. A counter-movement jump performed at rest and 2 min after the aerobic test differed significantly (P 相似文献   

Moderate-domain pulmonary oxygen uptake kinetics and endurance running performance

The aims of this study were to determine if the primary time constant (tau) for oxygen uptake (VO2) at the onset of moderate-intensity treadmill exercise is related to endurance running performance, and to establish if tau could be considered a determinant of endurance running performance. Thirty-six endurance trained male runners performed a series of laboratory tests, on separate days, to determine maximal oxygen uptake (VO2max), the ventilatory threshold (VT) and running economy. In addition, runners completed six transitions from walking (4 km x h-1) to moderate-intensity running (80% VT) for the determination of the VO2 primary time constant and mean response time. During all tests, pulmonary gas-exchange was measured breath-by-breath. Endurance running performance was determined using a treadmill 5-km time-trial, after which runners were considered as combined performers (n=36) and, using a ranking system, high performers (n=10) and low performers (n=10). Relationships between tau and endurance running performance were quantified using correlation coefficients (r). Stepwise multiple regression was used to determine the primary predictor variables of endurance running performance in combined performers. Moderate correlations were observed between tau, mean response time and endurance running performance, but only for the combined performers (r=-0.55, P=0.001 and r=-0.50, P=0.002, respectively). The regression model for predicting 5-km performance did not include tau or mean response time. The velocity at VO2max was strongly correlated to endurance running performance in all groups (r=0.72 - 0.84, P < 0.01) and contributed substantially to the prediction of performance. In conclusion, the results suggest that despite their role in determining the oxygen deficit and having a moderate relationship with endurance running performance, neither tau nor mean response time is a primary determinant of endurance running performance.