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ICA在糖尿病诊疗中的应用研究
引用本文:杨策尧,赵淮.ICA在糖尿病诊疗中的应用研究[J].昆明医学院学报,1999,20(4):49-51.
作者姓名:杨策尧  赵淮
作者单位:昆明医学院第一附属医院!昆明650032
基金项目:云南省应用基础研究基金
摘    要:用免疫酶法分析了糖尿病患者及甲状腺疾病患者血清中胰岛细胞抗体(ICA)的水平。结果为经胰岛素吸收后,IDDM组阳性率为46.7%(最高),NIDDM组阳性率为13.3%,甲状腺疾病组(其中1例Graves’病伴糖尿病ICA阳性)阳性率为4%,健康组0。统计学分析,P〈0.05,具有显著性差异,表明ICA是Ⅰ型糖尿病的特异性免疫标志物,ICA检测作为对IDDM与NIDDM的鉴别诊断,特别是对LADA

关 键 词:胰岛细胞抗体  鉴别诊断  特异性  糖尿病

A Study of Islet Cell Antibodies in the Therapy and Diagnosis of Diabetes
Yang Cerao,Zhao Huai,Ying Weizen.A Study of Islet Cell Antibodies in the Therapy and Diagnosis of Diabetes[J].Journal of Kunming Medical College,1999,20(4):49-51.
Authors:Yang Cerao  Zhao Huai  Ying Weizen
Abstract:Islet cell antibodies (ICA) were evaluated using standard ABC methods (Immunolabelling). The statistical analysis shows that the positive rate of ICA of IDDM is the highest after resorption of insulin. The positive rate of IDDM, NIDDM, thyroid disease,healthy person was respectively 46 7%, 13 3%, 4%, 0 respectively( P <0 05). There ws notable difference. The data presented in this report show that ICA is specificity antibody in IDDM. ICA determination is especially important in distinguishing IDDM and LADA from NIDDM.
Keywords:ICA  Differential diagnosis  Specificity
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