| 山楂水提物对肠易激综合征大鼠血浆胃动素的影响 |
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| 引用本文： | 武蕾蕾,高忠良,何志鹏.山楂水提物对肠易激综合征大鼠血浆胃动素的影响[J].牡丹江医学院学报,2011,32(2):10-12. |
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| 作者姓名： | 武蕾蕾 高忠良 何志鹏 |
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| 作者单位： | 1. 牡丹江医学院药学院,黑龙江,牡丹江,157011
2. 牡丹江市北方医院,黑龙江,牡丹江,157000 |
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| 摘 要： | 目的：探讨山楂水提物对肠易激综合征（IBS）大鼠血浆胃动素（MTL）水平的影响,探讨其改善消化功能的作用机制。方法：采用乳鼠结肠PTCA球囊刺激法制造IBS大鼠模型。采用放射免疫法检测血浆MTL水平。结果：山楂水提物可明显降低IBS模型大鼠血浆MTL水平（P〈0.01;P〈0.05）尤其以中剂量最为显著。结论：山楂水提物在一定剂量范围内可显著降低IBS大鼠血浆MTL水平,改善IBS大鼠肠道消化功能作用。
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| 关 键 词： | 山楂水提物 肠易激综合征 胃动素（MTL） |
EFFECTS OF FOLIUM CRATAEGI WATER EXTRACT ON PLASMA MTL LEVEL OF IBS MODEL RATS |
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| Wu Leilei et al.EFFECTS OF FOLIUM CRATAEGI WATER EXTRACT ON PLASMA MTL LEVEL OF IBS MODEL RATS[J].Journal of Mudanjiang Medical College,2011,32(2):10-12. |
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| Authors: | Wu Leilei |
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| Affiliation: | Wu Leilei et al(Pharmacy Department,Mudanjiang Medical College Mudanjiang 157011,China) |
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| Abstract: | Objective:To observe the effects of Folium Crataegi water extract on plasma motilin(MTL) level of rats with irritable bowel syndrome(IBS) and explore its possible mechanism of improving digestion.Methods:The IBS rats model was established by colonI irritation(Cl) during Postnatal development.The plasma MTL levels in each group was detected by radio-immunity method.Results:Folium Crataegi water extract can significantly reduce plasma MTL level of IBS rats(P<0.01:P<0.05).The effect of middle dose Folium Crata... |
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| Keywords: | Folium Crataegi water extract Irritable Bowel Syndrome Motlilin |
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