脑解剖微结构异常变化的CT与MRI比较研究对脑缺血的评估及预测

目的：通过对脑解剖微结构的异常征象研究，以观察脑缺血的程度和预测可能会发生的急性脑事件。材料与方法采用脑缺血CT、MRI比较影像学的方法，对近3年来收治的脑缺血性脑损伤患者1786例进行系统性回顾研究。其中385例在首诊CT检查图像为正常或可疑，并于7 d内又复查CT和MRI。结果385例首诊CT图像正常或可疑，7 d内再复查CT或MRI均证实发生了新的脑梗死灶。而这些病例的首诊CT图像上的脑解剖微结构的变化是可以预测可能发生的脑急性缺血事件的。另5例首次CT异常，又于24 h和30 h复查MRI（DWI）却未发现异常信号。结论应用CT/MRI比较影像学方法可以有效地评估脑缺血的存在。

The comparative study of CT and MRI about brain anatomic microstructure anomalous changes on assess and predict cerebral ischemia

Objective： To observe the degree of cerebral ischemia and to predict the acute cerebral ischemia that may be happen by studying the brain anatomic microstructure anomalous. Materials and Methods：Do the systematic reviews on 1786 cases with cerebral ischemia in our hospital nearly three years. The first CT images of 385 cases present normal or suspicious, and reexamination CT and MRI within 7 days. Results： 385 cases that be diagnosised normal or suspicious by the ifrst CT images happened new infarction after reexamination CT/MRI within 7 days. The brain anatomic microstructure anomalous on the ifrst CT images can predict the occur of acute cerebral ischemic events. In addition, 5 patients were diagnosised abnormal on the ifrst CT images, and presented normal on MRI （DWI） images that reexamination in 24 hours and 30 hours respectively. Conclusion：To evaluate the existence of cerebral ischemia by using of CT/MRI imaging methods.