液相色谱—串联质谱法测定大米、小麦粉中灭草松及其代谢物残留量

采用通用的QuEChERS净化法,建立以液相色谱—串联质谱测定大米和面粉中灭草松及其代谢物6-羟基灭草松和8-羟基灭草松残留量的方法。结果表明,当浓度为0.1~100.0μg/kg时,灭草松及其代谢物与浓度的线性关系良好,相关系数均>0.995,试验方法的定量限为0.2μg/kg,平均加标回收率为89.6%~106.9%,相对标准偏差为1.4%~11.7%(n=6)。该检测方法适用于大米和面粉等粮食中灭草松及其代谢物6-羟基灭草松和8-羟基灭草松残留量的检测和确证。

The determination of residues of bentazone and its metabolites in rice and wheat flour by high-performance liquid chromatography-MS/MS

A general QuEChERS purification method was used to establish an HPLC-MS/MS method for the determination of Bentazone and its metabolites 6-hydroxymetazone and 8-hydroxymetazone residues in rice and flour.The results showed that the calibration curves had a good linear relationship between bentazone and its metabolites in the range of 0.1 to 100.0μg/kg,and the linear correlation coefficients(R~2)were all greater than0.995,with the limits of quantification were all 0.2μg/kg.Methods at the levels of 0.2μg/kg,0.4μg/kg and 2μg/kg,the average recovery rates were between 89.6%and 106.9%,and the relative standard deviations were between 1.4%and 11.7%(n=6).The detection method was fast,high sensitivity,accurate and accurate,and the results are stable.It was suitable for the determination and confirmation of Bentazone and its metabolites 6-hydroxy-10-propafenone and 8-hydroxy-1-propafenone residues in rice and flour.