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凹凸棒石粘土口服制剂治疗消化道粘膜病变临床观察
引用本文:王唯坚,肖正达,谢宇野,蔡定国,曾华武,张兵.凹凸棒石粘土口服制剂治疗消化道粘膜病变临床观察[J].海军医学杂志,2002,23(1):24-26.
作者姓名:王唯坚  肖正达  谢宇野  蔡定国  曾华武  张兵
作者单位:1. 解放军第四一一医院消化内科,上海,200081
2. 海军药研中心,上海,200081
摘    要:目的 :评价凹凸棒石粘土 (attapulgiteclay)制剂对消化道粘膜病变疗效及应用前景。 方法 :用凹凸棒石粘土口服制剂治疗消化道粘膜病变 6 9例 ,其中急性胃肠炎 31例 ,慢性结肠炎 16例 ,溃疡性结肠炎 11例 ,消化性溃疡 11例 ,比较各组治疗前后症状积分 ,计算各组有效率 ,观察副反应。结果 :各组治疗前后症状积分相差显著 (P <0 .0 5 ) ,总有效率达 73.9%。结论 :凹凸棒石粘土制剂对消化道粘膜病变治疗疗效较满意 ,应用前景广泛。

关 键 词:凹凸棒石粘土  消化粘膜病变  消化性溃疡  治疗  口服制剂
文章编号:1009-0754(2002)01-0024-03
修稿时间:2001年8月28日

Clinical Observation of the Effects of Attapulgite Clay on Gastrointestinal Mucosal Diseases
WANG Wei jian,XIAO Zheng da,XIE Yu ye,et al.Clinical Observation of the Effects of Attapulgite Clay on Gastrointestinal Mucosal Diseases[J].Journal of Navy Medicine,2002,23(1):24-26.
Authors:WANG Wei jian  XIAO Zheng da  XIE Yu ye  
Abstract:Objective: A clinical observation was made to examine the therapeutic effects of attapulgite clay on gastrointestinal mucosal diseases. Methods: 69 patients with gastrointestina mucosal diseases, divided into four groups, were treated by attapulgite clay. The acute gastroenteritis group included 31 patients. The chronical colitis group 16 patients. The ulcerative colitis 11 patients. The digestive ulcer group 11 patients. The pre therapy and post therapy symptom integrals were compared, and the therapeutic effects of the drug were evaluated. Results: The symptom integral of post therapy was significantly reduced, compared with that of pre therapy (P<0.05). The effective rate of the drug was 73.9%. Conclusion: Attapulgite clay is one of the much effective drugs for gastrointestinal mucosal diseases, and its usage perspective is encouraging.
Keywords:attapulgite clay  gastrointestinal mucosal disease  ulcerative colitis
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