| 黄芩中黄酮类成分在组织损伤中抗氧化作用的研究进展 |
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| 引用本文： | 高平章,吴洪,黄俊来,高中洪.黄芩中黄酮类成分在组织损伤中抗氧化作用的研究进展[J].海峡药学,2009,21(6):1-4. |
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| 作者姓名： | 高平章 吴洪 黄俊来 高中洪 |
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| 作者单位： | 1. 泉州师范学院,分子生物与药物化学福建省高校重点实验室,泉州,362000
2. 华中科技大学,生物无机化学与药物湖北省重点实验室,武汉,430074 |
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| 基金项目： | 国家自然科学基金，福建省教育厅科技项目，泉州师范学院校级自选课题 |
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| 摘 要： | 对黄芩中黄酮类成分抗氧化药理作用的研究进展进行综述，为开发中药抗氧化新药提供理论依据。研究表明，黄芩在脑损伤、神经细胞损伤、心肌损伤、肝损伤等疾病中具有抗氧化作用。黄苓有望开发成为安全有效的中药抗氧化新药，但对其体内抗氧化作用机制的研究需要进一步深入。
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| 关 键 词： | 黄芩 黄酮 组织损伤 抗氧化 药理作用机制 |
Progress in studies of antioxidative mechanism of flavonoids extracted from Scutellaria baicalensis Georgi in tissue injury |
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| GAO Ping-zhang,WU Hong,HUANG Jun-lai,GAO Zhong-hong.Progress in studies of antioxidative mechanism of flavonoids extracted from Scutellaria baicalensis Georgi in tissue injury[J].Strait Pharmaceutical Journal,2009,21(6):1-4. |
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| Authors: | GAO Ping-zhang WU Hong HUANG Jun-lai GAO Zhong-hong |
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| Affiliation: | GAO Ping-zhang1,WU Hong1,HUANG Jun-lai,GAO Zhong-hong2(1.The key Laboratory of Molecular Biology &Medicinal Chemistry for Fujian higher education,Quanzhou Normal University,Quanzhou 362000,China,2.Hubei Key Laboratory of Bioinorganic Chemistry & Materia Medica,Huazhong University of Science & Technology,Wuhan 430074,China) |
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| Abstract: | The progress in the research of antioxidative mechanism of flavonoids extracted from Scutellaria baicalensis Georgi was summarized,which provides the theory basis to development new antioxidative traditional Chinese drugs.It was demonstrated by pharmacological experiments that Scutellaria baicalensis Georgi and its extracts exhibited significant antioxidative and free-radical scavenging activities in tissue injury-including cardiomyocytes injury,liver injury,brain injury and neurocytes injury.Scutellaria ba... |
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| Keywords: | Scutellaria baicalensis Georgi Flavonoids Tissue injury Anti-oxidant Pharmacological mechanism |
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