Effect of pulsating local negative pressure with oxygen on bioelectrical activity of the uterus in pregnant albino rats with intrauterine streptococcal infection

Bloodborne intrauterine streptococcal infection of albino rats during pregnancy (implantation, placentation) leads to disturbances of uterine bioelectrical activity which are restored to normal by treatment with pulsating local negative pressure together with periodic administration of oxygen.Moscow Regional Research Institute of Obstetrics and Gynecology and Department of Normal Physiology, Patrice Lumumba Peoples' Friendship University, Moscow. (Presented by Academician of the Academy of Medical Sciences of the USSR V. D. Timakov.) Translated from Byulleten' Éksperimental'noi Biologii i Meditsiny, Vol. 85, No. 5, pp. 528–531, May, 1978.     

Novel intronic variant in PALB2 gene and effective prevention of Fanconi anemia in family

Familial Cancer - Despite the acceptance of NextGen sequencing as a diagnostic modality suitable for probands and carriers of Mendelian diseases, its efficiency in identifying causal mutations is...     

Sodium-23 solid-state nuclear magnetic resonance of commercial sodium naproxen and its solvates

We report on the investigation of sodium coordination environments with solid-state 23Na nuclear magnetic resonance (NMR) spectroscopy of various hydrates and solvates of sodium naproxen (SN), a commercially available anti-inflammatory drug sold over the counter as Aleve?, among other names. The 23Na quadrupolar coupling constant is found to change significantly depending on the hydration state, and subtle changes in oxygen coordination environment about the sodium cations were apparent in the NMR spectra. High-resolution double-rotation NMR experiments are also performed on powdered samples to obtain solution-like 23Na NMR spectra. Our attempts at crystallizing various solvates of SN have led to the characterization of the first crystal structure for the heminonahydrated form. The composition of commercial SN is also investigated and it is shown that Aleve? is composed of approximately 80% monohydrate solvate. Density-functional theory calculations, using the gauge-including projector-augmented-wave formalism, allow for the assignment of 23Na NMR peaks to specific sodium sites in the reported X-ray crystal structure.     

Visual Attention to Ambiguous Emotional Faces in Eating Disorders: Role of Alexithymia

Eating disorders (EDs) are often accompanied by social–emotional problems. Recently, alexithymia has been suggested to explain objective emotion processing deficits in EDs. We tested if elevated levels of alexithymia may explain emotional face‐processing problems in a mixed ED group (N = 24, 19 with anorexia and five with bulimia), comparing them with high‐alexithymic (N = 25) and low‐alexithymic healthy controls (N = 25). Participants judged the mixture ratio of clear and ambiguous facial emotion blends while eye movements were recorded. The ED group was less accurate judging ambiguous blends containing anger or disgust and attended less to the faces compared with low‐alexithymic controls. Reduced attention to faces, in particular the eye region, was linked to confusion with ambiguous anger and disgust in the ED group only. Although significant group differences only emerged compared with low‐alexithymic controls, the visual attention patterns underlying the ED group's problems with subtle anger and disgust expressions were not driven by alexithymia. Copyright © 2017 John Wiley & Sons, Ltd and Eating Disorders Association.     

The Polyus-3 device for magnetotherapy and magnetophoresis

Scientific-Research Institute for Medical Instrument Engineering, Moscow. Translated from Meditsinskaya Tekhnika, No. 2, pp. 46–48, March–April, 1993.