皮肤病学文献数据库及其检索系统的初步研究

本文介绍了应用FOXBASE2.1中文数据库设计、建立的皮肤病文献专题数据库及其检索系统。该系统具有多种检索方式,可提供著者、分类、关键词等项目的检索,并具有数据的追加、修改、删除、查询、备份及打印等功能。     

记忆合金环抱器在复杂骨折治疗中的应用

对于一些特殊类型骨折以及严重的粉碎性骨折，传统的内、外固定方式难以固定，或固定效果不确切，不利于早期功能锻炼，影响骨折的愈合。NiTi记忆合金是近年来应用于骨折固定的新型内固定材料，自1998～2003年我们采’用记忆合金环抱器治疗各种复杂骨折17例，取得了满意的疗效。     

阴式子宫切除＋阴道前后壁修补术的手术配合

目的探讨阴式子宫切除＋阴道前后壁修补术的护理配合技术，以确保手术达到满意的效果。方法分析总结13例该手术的护理配合经验。结果13例阴式子宫切除＋阴道前后壁修补术均获得满意效果。结论护士掌握阴道及子宫的解剖学、手术步骤以及配合特点、特殊器械的使用，严格执行无菌原则和应用无菌技术，是避免术后并发症，确保手术成功的重要环节。     

RGD多肽接枝聚复合导管桥接神经缺损的实验研究

Objective To investigate the effect of RGD peptide conjugated poly[ LA-(Glc-Lys) ]/βTCP/PLA nerve conduit for bridging peripheral nerve regeneration defect. Methods Forty-five male Wister rots were randomly divided into 3 groups, with 15 rats each. A 10 mm defect was created in the right sciatic nerve. In group A the gap was bridged by PLA tube. In group B RGD peptide conjugated poly[ LA-(Glc-Lys) ]/β-TCP/PLA nerve conduit was used to repair the defect. Autologous nerve graft was done in group C which served as control. Twelve weeks postoperatively nerve regeneration was evaluated by gross observation,electrophysiology, muscle weight and muscle morphometry of triceps surae, and ultrastructure of the regenerating nerve. Results Twelve weeks after the operation, nerve conduction velocity and muscle weight recovery of group B were better than those of group A. The differences were statistically significant( P < 0.05). There was no significant difference between group B and group C ( P > 0. 05). The results of histology and ultrastructure showed that nerve regeneration in group B and group C was significantly superior to that in group A.Conclusion RGD peptide conjugated poly[LA-(Glc-Lys)]/β-TCP/PLA conduit can achieve similar results in repairing sciatic nerve defect to that of autogentic nerve graft. It may be an ideal material to repair nerve defect.     

空心加压螺纹钉结合钢丝治疗髌骨体部横形骨折

髌骨骨折在骨科领域属常见骨折，一般累及髌骨的中1/3，常伴有分离移位，需手术内固定治疗。由于是关节内骨折，后关节面不平整容易造成创伤性关节炎，故对复位要求较高。单纯钢丝环扎因固定欠牢靠，需辅助长时间外固定，不利于膝关节早期功能锻炼，目前逐步摒弃而被张力带取代。我院自2003年2月至2006年10月采用2枚空心加压螺纹钉结合钢丝治疗髌骨体部横形骨折25例，取得良好效果。[第一段]     

THE ACTION OF RADIX REHMANNIAE AND PLASTRUM TESTUDINIS ON BETA- ADRENERGIC RECEPTOR-cAMP SYSTEM

Mouse and rat pathological models were pro duced by injections of thyroid hormone (T3 0r T4, Model. I) or hydrocortisone (HC, Model II). A single subcutaneous dose of isoproterenol (ISO) caused plasma cAMP to peak in 5-15 min which was significantly higher in mouse Models I and II than in normal mice. Daily oral administration of a decoction of two Yin tonics-Radix Rehmanniae (RR) and Plastrum Testudinis (PT) reduced peak cAMP in both models. 3H.DHA binding assay re vealed significant elevations of the number of 3 adrenergic receptors in rat Models I and II. Decoc- tion RR and PT restored the peaks to normal range. Yang tonics Radix Aconiti praeparata (RAP) and Cortex Cinnamomi (CC) showcd contradictory effects on these models. It seems unlikely that the action of the two tonics promotes the dlearance of injected hormones, since injected hormone RIA iii plasma showed no differences between Yin tonics treated and untreated models. The therapeutic effects of these two Yin tonics on "Yin deficiency" syndrome of hyperthyroidism or hyperfunction of the adrenal cortex is very probably related to their actions on the O-adrenoreceptor-cAMP system as stated.     

从解剖角度探讨成年女性腹腔镜腹股沟疝修补术中子宫圆韧带的处理

<正>腹股沟疝发病人群中女性仅占6%^[1],其发生机制和临床特点与男性有着较大差异。女性腹股沟疝中股疝比例高达26.07%,远高于男性的5.09%^[2],因此发生嵌顿的比例也比较大。以往由于对女性腹股沟疝的解剖结构和临床特点认知不足,导致女性腹股沟疝的手术策略和技术基本同于男性。     

CT动态增强扫描对肺内孤立性小结节的鉴别诊断价值

目的 探讨动态增强CT扫描对肺内孤立性小结节的鉴别诊断意义。方法 经手术病理证实肺内孤立小结节60例，其中小肺癌38例，炎性结节10例，结核球12例，术前均行CT平扫及注药后30S、1min、2min、3min、4min、5min、6min的动态增强扫描。根据病灶平扫CT值及不同时间增强扫描CT值，做出不同病变CT值的时间一密度曲线。结果 小肺癌与结核、炎症的平扫CT值无显著差异。结核球的强化程度明显低于小肺癌和炎性结节，但炎性结节与小肺癌的CT强化程度无显著差异。小肺癌、炎性结节和结核球三种病变增强后的时间-密度-曲线形态和强化形式不同。结论 动态增强CT扫描对肺内孤立性小结节鉴别诊断有一定意义。     

邓铁涛教授的中医现代化思想

邓铁涛教授指出:中医现代化应按中医学自身的发展规律,沿着验、便、廉的方向,同时与现代最新的科技相结合,从理论上争取有突破性的发展;出现“泡沫中医”现象的原因在于按西医之模式来改造中医;要实现中医药的更快发展,中医药工作者必须具有强烈的献身精神,正确认识中医,加强中医中药的临床实践,同时重视哲学方法的指导作用,注重吸收现代新技术新方法。