巴曲酶与噻氯匹啶联用治疗脑梗死30例疗效观察

2002年1月～2002年8月,我院联用巴曲酶与噻氯匹啶治疗脑梗死30例,对其疗效进行观察,并与蝮蛇抗栓酶组进行比较,现将结果报告如下。 一般资料:本组60例脑梗死患者,均经神经系统检查及头颅CT确诊。入组标准:发病3天,首次发病或既往发病均     

急性冠状动脉综合征与高敏C反应蛋白相关性研究

Objective To investigate the relation among triglyce ride (TG), low density lipoprotein cholesterol(LD-C) and high sensitivity C reactive protein(hs-CRP) in acute coronary syndrome(ACS). Methods A total of 132 coronary heart disease patients which were divided as ACS and stable coronary heart dis-ease(SCHD)groups and 65 cases of the health physical exam inees were enrolled as the controls. The levels of hs-CRP, TG,HDL-C and LDL-C among the three groups were analyzed. Results The levels of hs-CRP of patients in ACS and SCHD groups were significantly higher than those in controls group(P ＜0.05). The level of hs-CRP in ACS group was obviously higher than that in SCHD group( P ＜0.01 ). There was a significant correlation between the concentration of hsCRP and TG( r = 0.62 ,P ＜ 0.01 ); there was a significant correlation between hs-CRPand LDL-C ( r =0.41, P ＜ 0.01 ); however there was a significantly negative correlation between hs-CRP and HDL-C ( r = -0.54, P ＜0.01 ). Conclusions The hs-CRP level in patients with acute coronary syndrome is obviously increased. hs-CRP is positively correlated with acute coronary syndrome, hs-CRP is the unstable sign of atheromatous plaque.     

肾动脉自发性夹层伴血栓形成致双肾梗死一例

1 临床资料 男性患者,39岁.因腰腹痛伴血压升高1个月入院.患者1个月前无明显诱凶出现右下腹持续性疼痛,时轻时重,体温37.7℃,最高达38.9℃.疼痛持续3～4天,右下腹疼痛缓解,转为左腰部疼痛,亦呈持续性.于当地省级医院就诊,磁共振成像(MRI)提示舣肾梗死.患者发病伴有血压升高,最高150/100 mmHg(1 mmHg=0.133 kPa),间断服用降压药,血压维持在140/100 mmHg,为进一步诊断治疗而我来院.既往无高血压史,否认高血压家族史.吸烟史5年,20支/日,偶饮酒少量.     

冠状动脉支架植入术后支架再狭窄相关因素的临床分析

目的分析冠心病经冠状动脉支架植入术后支架再狭窄（ISR）的相关因素。方法选择接受冠状动脉支架植入术并于6个月后按时随访的患者212例,根据随访的冠脉造影结果分为支架内再狭窄组（ISR组）102例及无支架内狭窄组（非ISR组）110例,单因素分析2组患者年龄、性别、体质量指数、并发症、生化检查及冠脉造影结果等资料的差异。采用二变量Logistic分析其与冠脉内支架再狭窄的关系。结果与非ISR组比较,ISR组患者的吸烟、糖尿病、支架的长度〉30 mm、支架直径〈3.5 mm的比例都显著增加（P均〈0.05）,ISR组患者尿酸水平明显高于非ISR组（P〈0.05）,多因素Logistic分析示吸烟、糖尿病、尿酸、支架直径、支架部位与冠状动脉支架内再狭窄有关。结论吸烟、糖尿病、尿酸、支架直径、支架部位是冠状动脉支架植入术后支架内再狭窄重要的危险因素。     

急性冠状动脉综合征与高敏C反应蛋白相关性研究

Objective To investigate the relation among triglyce ride (TG), low density lipoprotein cholesterol(LD-C) and high sensitivity C reactive protein(hs-CRP) in acute coronary syndrome(ACS). Methods A total of 132 coronary heart disease patients which were divided as ACS and stable coronary heart dis-ease(SCHD)groups and 65 cases of the health physical exam inees were enrolled as the controls. The levels of hs-CRP, TG,HDL-C and LDL-C among the three groups were analyzed. Results The levels of hs-CRP of patients in ACS and SCHD groups were significantly higher than those in controls group(P ＜0.05). The level of hs-CRP in ACS group was obviously higher than that in SCHD group( P ＜0.01 ). There was a significant correlation between the concentration of hsCRP and TG( r = 0.62 ,P ＜ 0.01 ); there was a significant correlation between hs-CRPand LDL-C ( r =0.41, P ＜ 0.01 ); however there was a significantly negative correlation between hs-CRP and HDL-C ( r = -0.54, P ＜0.01 ). Conclusions The hs-CRP level in patients with acute coronary syndrome is obviously increased. hs-CRP is positively correlated with acute coronary syndrome, hs-CRP is the unstable sign of atheromatous plaque.     

急性冠状动脉综合征与高敏C反应蛋白相关性研究

目的 观察不同类型急性冠状动脉综合征（ACS）患者血清TG、HDL-C、LDL-C水平变化及其与高敏C反应蛋白（hs-CRP）的关系,探讨临床识别和预测ACS的指标.方法 将132例冠状动脉粥样硬化性心脏病（冠心病）患者分为ACS组和稳定型冠心病组（SCHD组）,同时选择66例健康体检者作对照组,分别测定、比较3组的血清TG、HDL-C、LDL-C、hs-CRP水平.结果 ACS组和SCHD组患者血清hs-CRP水平[分别（9.26±10.98）mmol/L和（4.65±7.56）mmol/L]显著高于对照组[（1.21±1.32）mmol/L],差异有统计学意义（P＜0.05）.ACS组血清hs-CRP水平显著高于和SCHD组,差异有统计学意义（P＜0.01）.血清hs-CRP水平与TG含量呈显著正相关（r=0.62,P＜0.01）,与LDL-C含量亦呈明显正相关（r=0.41,P＜0.01）,与HDL-C含量呈显著负相关（r=-0.54,P＜0.01）.结论 ACS患者血清hs-CRP水平显著增高 hs-CRP水平与ACS的严重程度呈正相关,是动脉粥样硬化斑块不稳定的标志.     

脑出血早期血压变化对患者预后的影响

1999～ 2 0 0 2年 ,我院共收治脑出血患者 2 40例 ,均经 CT检查确诊。现将其中 12 0例患者的病例资料进行回顾性分析 ,旨在探讨脑出血早期血压变化对患者预后的影响。资料与方法 :本组男 80例 ,女 40例 ;发病年龄 3 4～ 84岁 ,平均 59岁。出血部位为基底节区 54例、丘脑 3 4例、外囊10例、额叶 4例、颞叶 5例、脑室 7例、小脑 4例、桥脑 4例。伴有意识障碍 96例 (昏迷 56例、嗜睡 40例 )。本组均予吸氧、降颅压、预防并发症等治疗措施。收缩压 >2 10 m m Hg者应用降压药物。记录患者发病 2小时内和治疗 6小时后的平均动脉压 ( MAP) ,即舒…     

地尔硫革治疗不稳定型心绞痛的疗效观察

不稳定型心绞痛(UAP)是一种严重并具有潜在危险的急性冠脉综合征，易发展为急性心肌梗死(AMI)或猝死，且内科常规药物治疗效果欠佳。我院自2002年8月起对30例UAP患者采用地尔硫革治疗，取得满意的疗效。现报告如下。     

半农半牧地区实施初保的困扰因素及对策

本文试从分析半农半牧地区实施初级卫生保健(PHC)主要的困扰因素入手,从而阐明针对这些困扰因素所应采取的基本对策。一、困扰因素1、“小卫生”,观念的束缚,淡化了社会卫生保健意识。翁牛特旗(以下简称翁旗)是一个具     

原发性高血压患者的心率变异性分析

目的:探讨原发性高血压患者心率变异性的变化。方法:观察76例原发性高血.压患者(观察组)和24例健康人(对照组)的24小时的心率变异性分析.结果:高血压组患者心率变异性时域指标(SDNN、SDANN、SDNNindex、I～SSD)较对照组明显降低,其差异性具有显著性(P<0.01)。结论:原发性高血压患者自主神经系统功能存在一定程度损害。