太和胶囊中挥发油包合物的制备

目的 研究β-环糊精包合肉桂、当归挥发油的最佳工艺。方法 采用正交实验法。结果 考察挥发油利用率、包合物收得率和含油率,优选出包合工艺。结论 挥发油与β-环糊精比例为1∶4(mL∶g),包结温度40 ℃,包结时间1 h为最佳工艺。     

头孢噻肟钠注射液的不良反应

注射用头孢噻肟钠为第三代头孢菌素，其抗菌作用强，抗菌谱广，主要用于敏感菌引起的各系统感染，不良反应少，发生率低。为引起临床注意，现综合报道如下。     

重症监护病房系统性红斑狼疮患者预后因素分析

Objective To analyze the outcomes and prognostic factors associated with the death of systemic lupus erythematosus (SLE) patients admitted to the intensive care unit (ICU). Methods During June 1996 to June 2007, all SLE patients admitted to the ICU were included. Patients were excluded if the diagnosis of SLE was established at or after ICU admission. A multivariate logistic regression model was applied using variables that were associated with death in the univariate analysis. Results A total of 101 patients meeting the criteria were included. The mortality rate was 48.6%. The most common causes of admission was lung disorder with acute respiratory distress syndrome (ARDS). Multivariate logistic regression analysis suggested that SLICC/ACR DI>7.7 (OR=6.87), APACHE Ⅲ≥21 (OR=29.8), lung disorders with ARDS (OR =55.81 ), septic shock (OR =32.22 ), intracranial haemorrhage (OR =57.35 ), hypocytopenia (OR = 5.89), mean equivalent prednisone dose>25 mg/d (OR=7.65) and prolonged tracheal intubation (OR=5.98) were signi-ficantly associated with death. Whereas sex, age, SLEDAI >27, gastrointestinal bleeding, the cumulative dosage of CTX higher than 1.0 g, pulse intravenous methylprednisolone therapy were not associated with death. Conclusion The mortality rate of critically ill SLE patients in ICU is very high. SLICC/ACR DI> 7.7, APACHE Ⅲ≥21, lung disorders with ARDS, septic shock, intracraniai haemorrhage, average prednisone equivalent dosage higher than 25mg/d and prolonged tracheal intubation (longer than 4 days) are negative prognostic factors in SLE patients admitted to the ICU.     

重症监护病房系统性红斑狼疮患者预后因素分析

Objective To analyze the outcomes and prognostic factors associated with the death of systemic lupus erythematosus (SLE) patients admitted to the intensive care unit (ICU). Methods During June 1996 to June 2007, all SLE patients admitted to the ICU were included. Patients were excluded if the diagnosis of SLE was established at or after ICU admission. A multivariate logistic regression model was applied using variables that were associated with death in the univariate analysis. Results A total of 101 patients meeting the criteria were included. The mortality rate was 48.6%. The most common causes of admission was lung disorder with acute respiratory distress syndrome (ARDS). Multivariate logistic regression analysis suggested that SLICC/ACR DI>7.7 (OR=6.87), APACHE Ⅲ≥21 (OR=29.8), lung disorders with ARDS (OR =55.81 ), septic shock (OR =32.22 ), intracranial haemorrhage (OR =57.35 ), hypocytopenia (OR = 5.89), mean equivalent prednisone dose>25 mg/d (OR=7.65) and prolonged tracheal intubation (OR=5.98) were signi-ficantly associated with death. Whereas sex, age, SLEDAI >27, gastrointestinal bleeding, the cumulative dosage of CTX higher than 1.0 g, pulse intravenous methylprednisolone therapy were not associated with death. Conclusion The mortality rate of critically ill SLE patients in ICU is very high. SLICC/ACR DI> 7.7, APACHE Ⅲ≥21, lung disorders with ARDS, septic shock, intracraniai haemorrhage, average prednisone equivalent dosage higher than 25mg/d and prolonged tracheal intubation (longer than 4 days) are negative prognostic factors in SLE patients admitted to the ICU.     

结缔组织病相关的肺动脉高压

结缔组织病(connective tissue disease,CTD)和动脉性肺动脉高压(pulmonary artery hypertension,PAH)关系密切,早期诊断和早期治疗对患者是非常重要的,关系到患者的预后。过去,PAH是心血     

经阴道彩色多普勒超声对宫颈疾病的诊断体会

目的本文分析各类宫颈疾病经阴道彩色多普勒超声声像特征，体会经阴道彩色多普勒超声对宫颈疾病的诊断价值。方法根据2003年6月至2006年12月止本院诊治各类型宫颈疾病的病例。分析其经阴道彩色多普勒超声的声像特征。结果本组76例，宫颈疾病中宫颈囊肿36例，其中纳氏囊肿34例，宫颈子宫内膜异位囊肿2例，宫颈息肉7例，宫颈带粘膜下子宫肌瘤2例，宫颈肌瘤9例，宫颈癌17例，宫颈妊娠3例，宫颈机能不全2例，经手术53例，宫颈镜检13例，宫颈刮片4例，超声与病理诊断符合率96％。结论经阴道彩色多普勒超声对诊断宫颈疾病方便、可靠、有效作为诊断宫颈疾病的首选检查方法。     

灯盏细辛治疗女性糖尿病患者周围神经病变

观察灯盏细辛对女性糖尿病患者的周围神经病变的治疗作用。47例女性2型糖尿病合并周围神经病变患者接受了灯盏细辛注射液治疗，治疗前后均进行了周围神经病变症状评分方法的评估。结果显示47例患者治疗后的各项评分均比治疗前有明显改善。提示灯盏细辛注射液治疗女性糖尿病合并周围神经病变患者较为有效。     

5羟色胺在肠易激综合征中的作用

肠易激综合征(IBS)是一个复杂的胃肠功能失调性疾病,包括胃肠动力、内分泌及内脏感觉等的异常.其临床特点为慢性的、或复发性的腹部疼痛或不适,包括排便习惯和大便性状异常,症状从轻到重.5羟色胺(5-HT)是一种广泛存在于中枢神经系统和胃肠道的神经递质,具有多种生物学功能.近年来其在调节胃肠道运动方面的作用逐渐受到重视,尤其在IBS发病机制及治疗中的作用受到越来越多的关注.     

骨穿针导向器的临床应用

目前采用手摇钻、电动骨钻、骨针叩击三种骨穿针方法。由于在穿针时没有支撑固定导向作用,使骨穿针在骨端、骨干形成上下、前后的偏斜,骨穿针偏斜度数越大,在骨穿针两端受力不一,对骨折端产生分力夹角越大,所以,直接影响到骨折的整复与骨延长的调节固定,临床上导致手术失败并不少见。为解决骨穿针不平行的缺陷,我们研制骨穿针导向器,解决了骨穿针的偏斜问题。一.骨穿针导向器的结构:由伸缩宽窄调节板,同步对称穿针导向管组成。据伤肢长短与周径大小调节,最长延伸32cm,最短调节9cm,最宽调节28cm,最窄调节8cm,穿针导向管同步对称调节高度25cm以内,导向管长10～15cm,穿针套管口径3.2、3.、4.2cm。