糖尿病性阳痿辩治规律探求

WHO有关资料表明，全球糖尿病患者已逾一亿，仅我国糖尿病患者约2000万人。全球男性成年患者约为700万人以上糖尿病阳痿的发生率约为35％～59％，和非糖尿病阳痿患者相比，糖尿病阳痿发生率较高。以至现代西医学把糖尿病列为阳痿发病病因之首。虽然糖尿病患者常有睾丸功能不全的表现，但近几年糖尿病阳痿内分泌因素已遭否定，一般认为与遗传、感染、免疫有关。     

成人特发性局灶节段性肾小球硬化病248例临床病理分析

目的 重新评价肾活检标本中特发性局灶节段性肾小球硬化病（FSGS）的发生率、主要临床及病理特点。方法 收集1994年7月～2000年7月间248例特发性FSGS的患者,观察肾组织的光镜、 荧光及电镜的特点,根据肾小球病变将特发性FSGS分为3种亚型。结果 248例成人特发性局灶节段肾小球硬化占同期肾活检的12.4%,占成年人原发性肾小球疾病的19.0%,以18～30岁为发病高峰年龄（约占44.4%）。临床表现为不同程度的蛋白尿,以肾病综合征为表现者143例（占57.7%)。FSGS的3种病理亚型中,经典型FSGS仍占绝大多数（91.5%),尖端型为4.4%,塌陷型为4.1%,肾活检时,约1/3以上为肾功能不全（约占35.1%）。13例尿毒症中76.9%病理亚型为塌陷型。结论 局灶节段性肾小球硬化病约占原发性肾小球病1/5,FSGS患者肾活检时,除表现为蛋白尿、肾病综合征外,肾功能不全也较常见。塌陷型FSGS常表现为进行性的不可逆的肾功能衰竭,其预后差。     

父亲的健脑舌头操

正不久前,回家看望父母,推开门,见母亲手捧一面圆镜子,坐在沙发上一动不动。走近一看,她嘴巴鼓鼓的。我以为她嘴里含了颗糖果,谁知母亲笑了起来,说:"我这是在做舌头操呢!这可是你父亲刚学会的健脑妙招!"3年前,母亲得了小中风,去医院检查时,医生说多亏发现得早,没有造成更严重的后果。虽然半年过后,母亲身体已恢复,     

血小板衍化生长因子B在糖尿病大鼠肾皮质中的表达

本研究以半定量RT-PCR法测定了糖尿病及对照Wistar大鼠肾皮质血小板衍化生长因子B(PDGFB)mRNA水平,发现糖尿病大鼠为对照组2.5倍,提示PDGFB在糖尿病肾病中起一定作用。     

老年2型糖尿病患者胰高血糖素对血糖、血压变化的反应

The response of glueagon to the change of glucose and its relation to blood pressure in 71 eidely patients with type 2 diabetes was investigated. The results showed that the postprandial increment of glucagon in the group of patients with postprandial 2h plasma glucose increment<2.5 mmol/L was significantly higher than that in the group with plasma glucose inerement≥ 2.5 mmoi/L (P<0. 05). The postprandial increment of glucagon in patients with normal blood pressure was significantly higher than that in patients with hypertension (P<0.05). The results suggest that the decreased response of glucagon to the change in plasma glucose in elderly patients with type 2 diabetes is related to increased blood glucose and high blood pressure.     

老年2型糖尿病患者胰高血糖素对血糖、血压变化的反应

The response of glueagon to the change of glucose and its relation to blood pressure in 71 eidely patients with type 2 diabetes was investigated. The results showed that the postprandial increment of glucagon in the group of patients with postprandial 2h plasma glucose increment<2.5 mmol/L was significantly higher than that in the group with plasma glucose inerement≥ 2.5 mmoi/L (P<0. 05). The postprandial increment of glucagon in patients with normal blood pressure was significantly higher than that in patients with hypertension (P<0.05). The results suggest that the decreased response of glucagon to the change in plasma glucose in elderly patients with type 2 diabetes is related to increased blood glucose and high blood pressure.     

老年2型糖尿病患者胰高血糖素对血糖、血压变化的反应

The response of glueagon to the change of glucose and its relation to blood pressure in 71 eidely patients with type 2 diabetes was investigated. The results showed that the postprandial increment of glucagon in the group of patients with postprandial 2h plasma glucose increment<2.5 mmol/L was significantly higher than that in the group with plasma glucose inerement≥ 2.5 mmoi/L (P<0. 05). The postprandial increment of glucagon in patients with normal blood pressure was significantly higher than that in patients with hypertension (P<0.05). The results suggest that the decreased response of glucagon to the change in plasma glucose in elderly patients with type 2 diabetes is related to increased blood glucose and high blood pressure.     

糖尿病性阳痿病因病机与临床实践的探索

糖尿病性阳痿是糖尿病的神经血管并发症之一。全世界现有糖尿病患者 1.35亿人。我国糖尿病患病率近 10年间增长了 3倍 ,患者总数达 30 0 0万人 ,成年男性患者近 10 0 0万 ,其中约 35 %— 5 9%并发阳痿。和非糖尿病患者相比 ,糖尿病患者的阳痿发生率高、出现时间早。一旦出现勃起神经病变 ,西医认为阳痿即不可逆转 ,所以西医把糖尿病列为阳痿病因之首。迄今为止 ,西医对糖尿病性阳痿发病机理仍未完全阐明 ,糖尿病与内分泌异常的因果关系尚不清楚。虽然糖尿病患者常有睾丸功能不全的表现 ,但近几年 ,糖尿病性阳痿的内分泌因素已被否定。一般认…     

中药治疗地塞米松注射液过敏反应致顽固性呃逆二例

地塞米松注射液是肾上腺皮质激素类药,有影响糖代谢、抗过敏、抗毒、抗休克等作用.溃疡病、血栓性静脉炎、糖尿病、进行性精神病、活动性肺结核患者慎用或忌用.长期应用可引起医源性柯兴氏综合征:满月脸、水牛背、浮肿、低血钾、血压升高、心动过速、精神欣快、毛发增多、痤疮、抵抗力低、骨质疏松、生长缓慢.本为抗过敏特效药,国内罕见其自身有过敏反应的报道.现将笔者门诊中遇见的2例因滴注地塞米松诱发顽固性呃逆并用中药治愈的情况报道如下: