935MHz微波电磁辐射对小鼠胚泡着床的影响

目的:探讨935MHz微波电磁辐射对小鼠胚泡着床的影响。方法:将受精后雌鼠暴露于不同强度、不同时间的935MHz微波辐射,采用逆转录聚合酶链反应法检测围着床期(受精后4d)子宫内膜白血病抑制因子(LIF)mRNA的表达。结果:570μW/cm2(4h/d)辐射组、1400μW/cm2(4h/d)辐射组与对照组相比,LIFmRNA表达均有显著降低(P<0.01),同时与二组强度各自2h/d辐射组比较也有明显减弱(P<0.01)。结论:935MHz微波电磁辐射可影响LIFmRNA表达,进而破坏胚泡着床,并具有一定的剂量反应关系及累积效应。     

氯诺昔康应用于经皮椎间盘减压术的临床观察

目的：观察评价氯诺昔康用于经皮椎间盘减压术（Percutaneous laster disc decompression,PLDD）的安全性及有效性。方法：将90例ASAⅠ～Ⅱ级的PLDD患者随机均分为A组、B组和C组,分别给予氯诺昔康、哌替啶、生理盐水进行肌肉注射,记录患者的血压、心率变化情况,同时由患者主观判断手术时的疼痛程度,从而判断3组药物用于PLDD的临床效果。结果：A组和B组镇痛效果确切,C组患者有明显疼痛感,A和B两组间视觉模拟评分（VAS）差异无统计学意义。B组头昏、恶心、呕吐发生率明显高于A组和C组。结论：氯诺昔康应用于PLDD术中,镇痛效果确切,无不良反应发生,且能发挥抗炎及抑制水肿作用,利于患者围术期平稳、安全和康复,值得临床推广。     

高效液相色谱-紫外检测法测定肾康超微粉胶囊中黄芪甲苷的含量

近年来对黄芪的研究越来越深入,更多地集中在其对补气、利尿作用方面,其被用来治疗糖尿病、肾病、糖尿病肾病、黄斑病变和动脉硬化症等。肾康超微粉胶囊包含了黄芪等十一味草药的复方中药制剂。     

Effect of 935-MHz phone-simulating electromagnetic radiation on endometrial glandular cells during mouse embryo implantation

This study examined the impact of 935MHz phone-simulating electromagnetic radiation on embryo implantation of pregnant mice.Each 7-week-old Kunming (KM) female white mouse was set up with a KM male mouse in a single cage for mating overnight after induction of ovulation.In the first three days of pregnancy,the pregnant mice was exposed to electromagnetic radiation at low-intensity (150 μW/cm2,ranging from 130 to 200 μW/cm2,for 2-or 4-h exposure every day),mid-intensity (570 μW/cm2,ranging from 400 to 700 μW/cm2,for 2-or 4-h exposure every day) or high-intensity (1400 μW/cm2,ranging from 1200 to 1500 μW/cm2,for 2-or 4-h exposure every day),respectively.On the day 4 after gestation (known as the window of murine embryo implantation),the endometrium was collected and the suspension of endometrial glandular cells was made.Laser scanning microscopy was employed to detect the mitochondrial membrane potential and intracellular calcium ion concentration.In high-intensity,2-and 4-h groups,mitochondrial membrane potential of endometrial glandular cells was significantly lower than that in the normal control group (P<0.05).The calcium ion concentration was increased in low-intensity 2-h group but decreased in high-intensity 4-h group as compared with the normal control group (P<0.05).However,no significant difference was found in mitochondrial membrane potential of endometrial glandular cells between low-or mid-intensity groups and the normal control group,indicating stronger intensity of the electromagnetic radiation and longer length of the radiation are required to inflict a remarkable functional and structural damage to mitochondrial membrane.Our data demonstrated that electromagnetic radiation with a 935-MHz phone for 4 h conspicuously decreased mitochondrial membrane potential and lowered the calcium ion concentration of endometrial glandular cells.It is suggested that high-intensity electromagnetic radiation is very likely to induce the death of embryonic cells and decrease the chance of their implantati     

绞窄性肠梗阻病理生理特点

急性肠梗阻是外科常见病。绞窄性肠梗阻是肠梗阻中最为危重的一种，本世纪初，肠梗阻的死亡率高达60％以上。半个多世纪来，由于对其病因、病理生理变化有了较多的了解，诊断和治疗水平亦有了明显的提高，其总的死亡率已降到10％以下，但绞窄性肠梗阻的死亡率仍达4．5％～30％。1肠管扩张静止时胸腔内正常压力为0．11～0．22kPa（2～4mmHg），单纯性肠梗阻时，腔内压可增至0．6～1kPa。在梗阻近侧产生反应性肠蠕动亢进性，肠腔内压力可增至2～4kPa，当压力超过2kPa可使淋巴管和毛细血管循环瘀滞；当压力超过4kPa时，肠管静脉回流受阻；若…     

12例急性苯中毒患者的抢救及护理

１２例急性苯中毒患者的抢救及护理刘文惠（附属弋矶山医院急诊科）我科于１９９３年１０月１３日诊治了１２例急性苯中毒病人。经及时抢救和护理，全部痊愈出院。现报告如下。１典型病例男，４３岁，油漆工。长期接触苯。１９９３年１０月１３日上午工作时感到头昏、气急...     

有机磷中毒病人的护理体会

我院自1991年3月～1996年8月共收治有机磷中毒28例，护理体会介绍如下。     

结扎子宫动脉上行支对剖宫产术出血的防治

目的：探讨结扎子宫动脉上行支对剖宫产术出血时的防治意义。方法：回顾性分析1998～2003年70例剖宫产术中出血或术后可能出血患者施行子宫动脉上行支结扎法的适应证，方法及效果等。结果：对55例剖宫产术中出血患者及15例可能术后出血患者施行了该术，其中单侧结扎11例，双侧结扎59例，所有病例止血效果满意，无晚期产后出血，1例并发阔韧带血肿。结论：正确掌握该方法需注意结扎时部位、深度、宽度、单双侧等。该方法止血简单迅速、效果确切。     

鼻窦CT测量在呼吸道上皮腺瘤样错构瘤术前诊断中应用

目的探讨鼻窦CT测量在呼吸道上皮腺瘤样错构瘤(REAH)术前诊断中的应用价值。方法选取自2013年1月至2018年9月在北部战区空军医院耳鼻咽喉科进行手术治疗的REAH患者54例为REAH组;选取同期住院经术后病理诊断鼻息肉的70例患者为NPS组;选取门诊以鼻中隔偏曲症状就诊、查鼻窦CT未见异常的70例成年人为Normal组。测量并比较各组患者的鼻窦冠状位CT的嗅裂前区顶部宽度、嗅裂前区宽度、前鼻腔总横径、中鼻甲间距离、嗅裂后区宽度、后鼻腔总横径,计算嗅裂前区宽度/前鼻腔总横径、嗅裂后区宽度/后鼻腔总横径、嗅裂前区顶部宽度/中鼻甲间距离的比值。结果三组患者的前鼻腔总横径、后鼻腔总横径比较,差异无统计学意义(P>0.05)。NPS组的中鼻甲间距离显著小于REAH组、Normal组,差异有统计学意义(P<0.05);且REAH组与Normal组比较,差异无统计学意义(P>0.05)。REAH组的嗅裂前区宽度、嗅裂后区宽度、嗅裂前区顶部宽度、嗅裂前区宽度/前鼻腔总横径、嗅裂后区宽度/后鼻腔总横径显著高于NPS组和Normal组,差异有统计学意义(P<0.05);且NPS组与Normal组比较,差异无统计学意义(P>0.05)。Normal组的嗅裂前区顶部宽度/中鼻甲间距离显著小于REAH组及NPS组,差异有统计学意义(P<0.05);且REAH组与NPS组比较,差异无统计学意义(P>0.05)。受试者工作特征曲线分析示,嗅裂前区宽度和嗅裂前区宽度/前鼻腔总横径的曲线下面积(AUC)值最大,且这两个指标的AUC比较,差异无统计学意义(P>0.05)。当嗅裂前区宽度取值0.78 cm或嗅裂前区宽度/前鼻腔总横径取值0.30,诊断的灵敏度和特异度均较高。结论鼻窦CT测量为REAH术前诊断提供帮助,嗅裂前区宽度≥0.78 cm或嗅裂前区宽度/前鼻腔总横径≥0.30是鉴别REAH和鼻息肉的参考依据。