全文获取类型
收费全文 | 2074篇 |
免费 | 106篇 |
国内免费 | 16篇 |
学科分类
医药卫生 | 2196篇 |
出版年
2023年 | 10篇 |
2022年 | 13篇 |
2021年 | 34篇 |
2020年 | 15篇 |
2019年 | 33篇 |
2018年 | 53篇 |
2017年 | 37篇 |
2016年 | 29篇 |
2015年 | 31篇 |
2014年 | 44篇 |
2013年 | 85篇 |
2012年 | 142篇 |
2011年 | 129篇 |
2010年 | 81篇 |
2009年 | 74篇 |
2008年 | 118篇 |
2007年 | 108篇 |
2006年 | 117篇 |
2005年 | 106篇 |
2004年 | 92篇 |
2003年 | 96篇 |
2002年 | 83篇 |
2001年 | 85篇 |
2000年 | 82篇 |
1999年 | 79篇 |
1998年 | 14篇 |
1997年 | 12篇 |
1996年 | 11篇 |
1995年 | 15篇 |
1994年 | 11篇 |
1993年 | 10篇 |
1992年 | 32篇 |
1991年 | 33篇 |
1990年 | 23篇 |
1989年 | 25篇 |
1988年 | 32篇 |
1987年 | 27篇 |
1986年 | 21篇 |
1985年 | 22篇 |
1984年 | 14篇 |
1983年 | 19篇 |
1980年 | 5篇 |
1979年 | 13篇 |
1978年 | 8篇 |
1977年 | 6篇 |
1975年 | 8篇 |
1974年 | 10篇 |
1970年 | 8篇 |
1969年 | 8篇 |
1968年 | 7篇 |
排序方式: 共有2196条查询结果,搜索用时 156 毫秒
1.
Raffaele Ferri Lourdes M. DelRosso Alessandro Silvani Filomena I. I. Cosentino Daniel L. Picchietti Paola Mogavero Mauro Manconi Oliviero Bruni 《Journal of sleep research》2020,29(3)
The objective of this observational cohort study was to analyse the age‐related changes of periodic leg movements during sleep using the newest international scoring rules, to expand past analyses, including patients in the paediatric age range, and also to analyse the changes of short‐interval and isolated leg movements during sleep throughout the lifespan. One hundred and sixty‐five patients (84 women) with restless legs syndrome were recruited in the following age groups: 16 preschoolers (≤5 years of age), 29 school‐age children (6–12 years), 19 adolescents (13–17 years), 17 young adults (19–40 years), 47 adults (41–60 years) and 37 seniors (>60 years). Total, periodic, short‐interval and isolated leg movements during sleep and periodicity indexes were obtained by polysomnography. The total index showed (quartic polynomial interpolation) a decrease before 10 years, followed by a steady increase up to 30 years, a relatively stable period until 60 years, and a final increase up to 80 years. This course was almost entirely due to changes in periodic movements. Isolated movements did not change significantly and short‐interval movements showed only an increase in seniors. Our study indicates that, in restless legs syndrome, the total index shows a peculiar and unique course throughout the lifespan, mainly due to periodic movements. These age‐related changes may mirror developmental changes in network complexity known to occur in dopaminergic circuits. These data further confirm the need to better assess the periodicity of leg movements in sleep during the human development period, in order to obtain clinically useful information. 相似文献
2.
3.
Clinical activity of ponatinib in one patient with chronic myeloid leukemia in chronic phase with e19a2 transcript and T315I mutation 下载免费PDF全文
4.
Deitelzweig Steve Luo Xuemei Nguyen Jennifer L. Malhotra Deepa Emir Birol Russ Cristina Li Xiaoyan Lee Theodore C. Ferri Mauricio Wiederkehr Danny Reimbaeva Maya Barnes Geoffrey D. Piazza Gregory 《Journal of thrombosis and thrombolysis》2022,54(4):696-696
Journal of Thrombosis and Thrombolysis - 相似文献
5.
Marica Ferri Sonia Dias Alessandra Bo Danilo Ballotta Roland Simon Giuseppe Carrá 《Drugs (Abingdon, England)》2018,25(2):198-204
Background: The EMCDDA, through its network of National Focal Points, collects information on the quality assurance systems for drugs-related interventions across European countries. European National Drug Strategies include recommendations for systems and approaches for the assurance of the quality of interventions.Methods: We searched National Drug Strategies for elements related to quality assurance in drug demand reduction and summarised information through questionnaires administered to the EMCDDA Network of National Focal Points.Results: In total, 15 National Drug Strategies and 60 questionnaires were analysed. Almost all the strategies include quality-related topics. Frequently, the Ministry of Health leads quality assurance although sometimes jointly with the Ministries of Education, Labour, Family and Social Welfare. Accreditation systems are common, but implemented in different ways. Training and education are widely provided, for the vast majority of countries, consisting of short-term training to keep professionals updated. Guidelines and Standards are gathering momentum as the major tools for the implementation of evidence-based recommendations and are usually available across countries.Conclusions: Although the evidence base for interventions in drug demand reduction is becoming available and accepted, attention needs to be given to implementation issues. The European countries are rapidly moving towards paying greater attention to the quality of interventions. 相似文献
6.
Negrini Simone Magnani Ottavia Matucci-Cerinic Marco Carignola Renato Data Valeria Montabone Erika Santaniello Alessandro Adorni Giuditta Murdaca Giuseppe Puppo Francesco Indiveri Francesco Della Rossa Alessandra D’Ascanio Anna Barsotti Simone Giuggioli Dilia Ferri Clodoveo Lumetti Federica Bosello Silvia Laura Canestrari Giovanni Bellando Randone Silvia Bruni Cosimo Guiducci Serena Battaglia Elisabetta De Andres Maria Ilenia Russo Alessandra Azzurra Beretta Lorenzo 《Clinical and experimental medicine》2019,19(3):357-366
Clinical and Experimental Medicine - Vasculopathy is a crucial feature of systemic sclerosis (SSc), and Raynaud’s phenomenon (RP) and digital ulcers (DU) have a deep impact on the quality of... 相似文献
7.
8.
Ruhin B Raoul G Kolb F Casiraghi O Lecomte-Houcke M Ghoul S Auriol M Ferri J 《International journal of oral and maxillofacial surgery》2007,36(9):864-866
A case of a maxillary osteolytic tumour is described in a 9-year-old boy. Histological analysis led to an initial diagnosis of benign squamous odontogenic tumour, although this was not straightforward due to swelling, and cellular pseudo-malignant and non-specific signs. Because of the young age of the patient, a local surgical tumourectomy was first chosen with respect to the mixed dentition. For 10 months, the evolution was satisfactory. Then, a very aggressive tumoural recurrence with lip and palate infiltration led to doubts as to the histologic nature of the tumour. Efficient collaboration between several specialized pathologist teams finally confirmed that this was a squamous odontogenic tumour but in a very aggressive form. Radical surgery was then carried out. 相似文献
9.
Cannizzaro G Felice P Soardi E Ferri V Leone M Esposito M 《European journal of oral implantology》2011,4(3):205-217
10.
Martina Gaia Cogo Stefania Rota Maria Letizia Fusco Cristina Mapelli Francesca Ferri Ildebrando Marco Appollonio 《Journal of clinical and experimental neuropsychology》2014,36(10):1066-1075
Introduction: Impairment of decision making in relapsing remitting multiple sclerosis is still controversial, and its neuropsychological correlates have never been explored thoroughly, especially in patients with minimal physical and cognitive deficits. In the present study we investigated the cognitive underpinnings of decision making under ambiguous and explicit conditions in patients with very mild relapsing remitting multiple sclerosis, using a dice and a card gambling game. Method: The study sample included 60 patients and 35 healthy subjects. In the Game of Dice Task, winning and losing probabilities are obvious to the subject, while in the Iowa Gambling Task they are initially ambiguous and have to be gradually identified. Performance at the two tasks was correlated with scores obtained at tests investigating cognitive processing speed, memory, language and executive functions. Results: Patients’ performance did not differ from that of controls at either gambling task. There was only a trend for them to be significantly slower than healthy subjects in progressively recognizing advantageous decks in the Iowa Gambling Task. While the Game of Dice was unrelated to neuropsychological tests, predictors of performance at the Iowa task were Letter Fluency and the Symbol Digit Modalities Test for the initial, under-ambiguity, trials and the Wisconsin Card Sorting Test for the last, purely under-risk, trials. Conclusions: Our results suggest that high-functioning patients with relapsing remitting multiple sclerosis are substantially capable of making advantageous decisions, even if they may be slower in processing options and shifting strategy when selection criteria are not explicit. 相似文献