“Isocyanide-less” Ugi/Intramolecular Diels-Alder reaction of 5-hydroxymethylfurfural

The one-pot, three-step, four-component Ugi-IMDAF reaction with 5-hydroxymethylfurfural provides simple access to hydroxymethyl-substituted epoxyisoindolones in a diastereoselective and stereospecific manner. The protocol avoids the transfer or isolation of isocyanides, and the broad scope was illustrated by the synthesis of 22 different compounds bearing various substituents on the heterocyclic core.     

Motion of a circular cylinder in a rectangular channel

When bodies move in fluids, the parameters of their motion depend strongly on the interaction of the bodies with the surrounding fluid [1, 2]. The present paper is devoted to determination of the hydrodynamic forces that act on a cylinder moving in an infinite rectangular channel in an ideal incompressible fluid that is at rest.     

低能质子束在氢等离子体中的能损研究

实验测量了100 keV的质子束穿过部分电离氢等离子体靶后的能量损失. 等离子体靶由气体放电方式产生, 其自由电子密度在10¹⁶ cm^-3量级, 电子温度约1–2 eV, 维持时间在微秒量级. 研究结果表明: 质子束在等离子体靶中的能量损失与自由电子密度密切相关且明显大于在同密度条件下中性气体靶中的能量损失; 在自由电子密度达到峰值处, 通过实验结果计算得到此时的自由电子库仑对数约为10.8, 与理论计算结果符合较好, 该值比Bethe公式给出的中性气体靶中束缚电子库仑对数高4.3倍,相应的能损增强因子为2.9.     

Data Acquisition and Diagnostic System for Prototype of PANDA Pellet Target

Physics of Atomic Nuclei - In the PANDA experiment of the FAIR project, it is proposed to use internal targets based on the hydrogen isotopes that provide a monodisperse regime of flow generation...     

On the possibility of in vitro estimation of physiological activities of pharmaceutical drugs containing the same active ingredient

We studied whether the physiological activities of several pharmaceutical products containing the same active ingredient (pantoprazole) can be estimated by the ealier proposed method, which is based on the study of drug effect on the structures of cell membranes (red blood cells, lymphocytes, and platelets) using ESR spectroscopy and spin probes. The properties of one innovator drug and four corresponding generics were compared. There are possible cases when the innovator drug has a higher effect on the structures of blood cell membranes than generics and when the pharmaceutical products have no any effect thereon. In the latter case, the number of side effects is assumed to be minimized.

     

Development of Ni–Mo Sorption-Catalytic Materials for Removing Arsenic Compounds from Middle Distillates

Possibility of using mesoporous materials for obtaining Ni–Mo sorption-catalytic materials for purification of medium-distillate fractions to remove arsenic-containing compounds was examined. It was shown that, in the course of hydropurification, the acidity of the mesoporous material does not directly affect the extent to which the amount of arsenic in hydrocarbons is diminished. It was found that mesoporous supports of the SBA-15, TUD, and MCF types reduce the content of arsenic to less than 0.5 ppm at 360°C and 50 atm of H₂.     

Formation of a quasi-hollow beam of high-energy heavy ions using a multicell resonance RF deflector

The generation of matter in an extreme state with precisely measurable parameters is of great interest for contemporary physics. One way of obtaining such a state is to irradiate the end of a hollow cylindrical shell at the center of which a test material is kept at a temperature of several Kelvin by an annular beam of high-energy heavy ions. Under the action of the beam, the shell starts explosively expanding both outwards and inwards, compressing the material to an extremely high pressure without subjecting it to direct heating. A method of producing a hollow cylindrical beam of high-energy heavy ions using a resonance rf deflector is described. The deflection of the beam in two transverse directions by means of an rf electric field allows it to rotate about the longitudinal axis and irradiate an annular domain on the end face of the target.