Self‐Assembly: I‐Motif Nanospheres: Unusual Self‐Assembly of Long Cytosine Strands (Small 8/2011)

The synthesis and characterization of novel DNA structures based on tetraplex cytosine (C) arrangements, known as i‐motifs or i‐tetraplexes, is reported. Atomic force microscopy (AFM) investigation shows that long C‐strands in mild acidic conditions form compact spherically shaped nanostructures. The DNA nanospheres are characterized by a typical uniform shape and narrow height distribution. Electrostatic force microscopy (EFM) measurements performed on the i‐motif spheres clearly show their electrical polarizability. Further investigations by scanning tunneling microscopy (STM) at ultrahigh vacuum reveals that the structures exhibit an average voltage gap of 1.9 eV, which is narrower than the voltage gap previously measured for poly(dG)–poly(dC) molecules in similar conditions.     

Object features, object locations, and object files: Which does selective attention activate and when?

The representation within which attention operates was investigated in 3 experiments. The task was similar to that of R. Egly, J. Driver, and R. D. Rafal (1994). Participants had to detect the presence of a target at 1 of 4 ends of 2 shapes, differing in color and form. A precue appeared at 1 of the 4 possible corners. The 2 shapes occupied either the same or different locations in the cuing and target displays. The results showed that the cued object location was attended whether or not space was task relevant, whereas the cued object features (color and form) were attended only when these were task relevant. Moreover, when object file continuity was maintained through continuous movement, attention was found to follow the cued object file as it moved while also accruing to the cued location. (PsycINFO Database Record (c) 2010 APA, all rights reserved)     

Inference of monotonicity constraints in Datalog programs

Datalog (i.e., function-free logic) programs with monotonicity constraints on extensional predicates are considered. A monotonicity constraint states that one argument of a predicate or a constant is always less than another argument or a constant, according to some strict partial order. Relations of an extensional database are required to satisfy the monotonicity constraints imposed on their predicates. More specifically, a strict partial order is defined on the domain (i.e., set of constants) of the database, and every tuple of each relation satisfies the monotonicity constraints imposed on its predicate. This paper focuses on the problem of entailment of monotonicity constraints in the intensional database from monotonicity constraints in the extensional database. The entailment problem is proven to be decidable, based on a suggested algorithm for computing sound and complete disjunctions of monotonicity and equality constraints that hold in the intentional database. It is also shown that the entailment of monotonicity constraints in programs is a complete problem for exponential time. For linear programs, this problem is complete for polynomial space. This revised version was published online in June 2006 with corrections to the Cover Date.     

Heat transfer efficiency in a fliuidized bed

The equilibrium stage concept used in staged contacting operations was adopted as a measure of heat transfer efficiency for a fluidized bed. A simple model was developed which postulates that solids flow through the bed can be by perfect mixing, plug flow and short-circuiting. Efficiencies were determined experimentally in a 150 mm diameter fluidized bed with air as the fluidizing medium and sand as the solid. Heat transfer efficiencies greater than 100% were obtained indicating that small diameter, low aspect ratio fluidized beds do not behave as perfect mixers. The results indicate that heat transfer measurements can be used to develop information on solids flow behavior.     

The effect of gender on left ventricular function immediately after the wingate test

The effect of gender on left ventricular systolic function and exercise haemodynamics in healthy young subjects was studied during 30-s all-out sudden strenuous dynamic exercise. A group of 22 men [19.3 (SD 1) years] 20 women [19.1 (SD 1) years] volunteered to participate in this study. Two-dimensional direct M-mode and Doppler echocardiograph studies were performed with the subject in the sitting position. The Doppler examination of flow was located with continuous-wave, interrogating ascending aorta measurements. The subjects completed the study without showing any electrocardiograph abnormalities. An interaction effect with stroke volume (P < 0.05) was characterized by a decrease in the men and an increase of stroke volume in the women. Cardiac output rose significantly (P < 0.05) up to 14.5 (SD 6) 1.min-1) for the men and 12.1 (SD 4) 1.min-1 for the women compared to the rest values [5.8 (SD 0.4) and 4.7 (SD 0.5) 1.min-1, respectively]. Flow velocity integral and acceleration time differed significantly between the two groups at rest (P < 0.05). During exercise these differences showed an interaction effect (P < 0.05). These results would indicate that normal men and women respond to sudden strenuous exercise by reducing their left ventricular systolic function, with a significantly greater decrease in women (P < 0.05). The gender differences in the haemodynamic responses during the present study, may, as suggested by others, be attributable to differences in energy metabolism. In addition, changes in Doppler parameters of aortic flow, haemodynamics and blood pressure responses during sudden strenuous exercise differed markedly from those seen before with endurance exercise.     

Computing access relevance for path-method generation in OODB and IM-OODB

A path-method (PM) is a mechanism to retrieve or to update information relevant to one class, in an object-oriented database (OODB), that is not stored with that class but with some other class. The PM traverses a chain of classes and connections that ends at the class where the required information is stored. However, it is a difficult task for a user to write PMs. This is because it might require comprehensive knowledge of many classes of the conceptual schema. But a typical user has often incomplete or even inconsistent knowledge of the schema. Currently we are developing a system, called Path-Method Generator (PMG), which generates PMs automatically according to a naive user's requests. One algorithm of PMG uses numerical access relevance between pairs of classes as a guide for the traversal of an OODB schema. In this paper we define the notion of access relevance to measure the significance of the (indirect) connection between any two classes in an OODB and present efficient algorithms to compute access relevance. The manual PM generation in an interoperable multi object-oriented database (IM-OODB) is even more difficult than for one OODB since a user has to be familiar with several OODBs. We use a hierarchical approach for developing efficient online algorithms for the computation of access relevances in an IM-OODB, based on precomputed access relevances for each autonomous OODB. In an IM-OODB the access relevances are used as a guide in generating PMs between the classes of different OODBs.     

The TSIMMIS Approach to Mediation: Data Models and Languages

TSIMMIS—The Stanford-IBM Manager of Multiple InformationSources—is a system for integrating information. It offers a datamodel and a common query language that are designed to support thecombining of information from many different sources. It also offerstools for generating automatically the components that are needed tobuild systems for integrating information. In this paper we shalldiscuss the principal architectural features and their rationale.     

Location dominance in attending to color and shape.

Investigated in 4 experiments whether Ss direct attention to stimulus location when attempting to attend to its color or shape. In the 1st 2 experiments, a given property (location, color, or shape) of a letter cue instructed Ss whether to report any letters from a subsequent display. Regardless of which property was relevant, Ss reported letters adjacent to the cue and not those similar to its color or shape. In the last 2 experiments, the varied location of a cue was irrelevant to the task, whereas its varied color instructed Ss to report a letter in a given location or of a given shape. Targets adjacent to the cue were reported faster than those remote from the cue. The results suggest that attempting to attend to any aspect of a stimulus entails directing attention to location. (PsycINFO Database Record (c) 2010 APA, all rights reserved)     

The attentional white bear phenomenon: The mandatory allocation of attention to expected distractor locations.

The authors devised a prestimulus-probe method to assess the allocation of attention as a function of participants' top-down expectancies concerning distractor and target locations. Participants performed the flanker task, and distractor locations remained fixed. On some trials, instead of the flanker display, either 2 simultaneous dots or a horizontal line appeared. The dot in the expected distractor location was perceived to occur before the dot in the expected empty location, and the line appeared to extend from the expected distractor location to the expected empty location, suggesting that attention is allocated to expected distractor locations prior to stimulus onset. The authors propose that a process-all mechanism guides attention to expected locations of all stimuli regardless of task demands and that this constitutes a major cause for failures of selective attention. (PsycINFO Database Record (c) 2010 APA, all rights reserved)     

Transient charge accumulation in a capacitive self-assembled monolayer

Charge accumulation in an organosilane monolayer self-assembled on silicon is studied using electron-spectroscopy-based chemically resolved electrical measurements (CREM). By resolving the net electrical response of the organic layer, a significant capability of holding extra charge is indicated. Quantum size effects at a molecularly thin layer and the role of competing discharge mechanisms, including defect-assisted leakage currents, are discussed.