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1.
Ergonomics assessment in the automotive industry has, to date, focused mainly on physical ergonomics, for example, manual handling and posture. However, workload and, in particular, metabolic and cognitive workload, contributes to worker efficiency but has not received sufficient attention to yield practical guidance for industry. Successful workload assessment requires in-depth understanding of the context in which it will be conducted and of the various assessment techniques which will be applied, with consideration given to factors such as feasibility, resources, and skill of the assessor. These requirements are met with challenges within large and complex organizations and are often dealt with in a piecemeal and isolated matter (i.e., reactive workload assessment). The present paper explores these challenges within the automotive manufacturing industry and aims to develop a decision matrix to guide effective selection of workload assessment techniques focused on metabolic and cognitive demands. It also presents the requirements for time, equipment, and knowledge to implement these techniques as part of a participatory ergonomics approach. Early findings suggest that most assessment techniques reviewed require further development, for example, to establish the acceptance criteria for the specific workload scenario. However, five methods (Garg, Borg RPE, IPAQ, SWAT, and NASA-TLX) are ready to use in certain applications. Ultimately, the findings suggest that it is possible to implement a participatory workload evaluation program within large and complex manufacturing plants.  相似文献   
2.
Branched polyethyleneimine (bPEI) was used to modify the surface of Fe3O4 nanoparticles coated with silica layer, and then, it was treated with ethyl iodide to prepare Fe3O4@SiO2@Ethylated‐bPEI. In the next step, the yolk–shell structure was gained by selectively etching the SiO2 middle layer. Finally, copper(I) was introduced to the yolk–shell Fe3O4@Ethylated‐bPEI and the activity of the catalyst was evaluated for atom transfer radical polymerization (ATRP) of styrene, led to obtain the well‐defined polymer with relatively low polydispersity. The toxicity of the residual copper in the polymer product was a limiting issue for applicability of ATRP reactions especially for biological purposes. In this report, the copper content in the polymer was reduced to the excellent value of 1.1 ppm. Moreover, the magnetic isolation, recyclability, and remove the need for an external ligand were other advantages of the synthesized catalyst which makes it suitable for employing in ATRP reactions. © 2015 Wiley Periodicals, Inc. J. Appl. Polym. Sci. 2015 , 132, 42337.  相似文献   
3.
Controlled degradation and transiency of materials is of significant importance in the design and fabrication of degradable and transient biomedical and electronic devices and platforms. Here, the synthesis of programmable biodegradable and transient insulating polymer films is reported, which have sufficient physical and chemical properties to be used as substrates for the construction of transient electronics. The composite structure can be used as a means to control the dissolution and transiency rate of the polymer composite film. Experimental and computational studies demonstrate that the addition of gelatin or sucrose to a PVA polymer matrix can be used as a means to program and either slow or enhance the transiency of the composite. The dissolution of the polymer composites are fitted with inverse exponential functions of different time constants; the lower time constants are an indication of faster transiency of the polymer composite. The addition of gelatin results in larger time constants, whereas the addition of sucrose generally results in smaller time constants.  相似文献   
4.
Ketoconazole is an important drug with low water solubility. Its low aqueous solubility could be increased using various methods such as by the addition of a pharmaceutical cosolvent. The solubility of ketoconazole in ethanol + water mixtures at 293.2, 298.2, 303.2, and 308.2 K were determined, and the results showed that the addition of ethanol increased the solubility and the maximum value was obtained at 80% of ethanol. The generated data were mathematically represented using the Jouyban–Acree model within an acceptable accuracy.  相似文献   
5.
Wound care has been a challenging subject for medical teams and researchers. Bacterial infections are one of the most serious complications in injured skins that often affect healing process. Antibacterial wound dressings can be used to facilitate wound healing process. The purpose of this study is to fabricate chitosan (Chito)/polyethylene glycol (PEG) antibacterial wound dressing doped with minocycline, and to evaluate the influence of composition ratio on the blending properties of the films. To improve the mechanical properties of these films, we examined various amounts of glycerol as a plasticizer. Moreover, we investigated morphological and mechanical aspects, water uptake, degradation, water vapor transmission and wettability properties of the films prepared with various ratios of Chito/PEG/Gly. Assessment of mechanical properties revealed that film containing 80:20 ratio Chito/PEG with 40 PHR Gly content exhibits the highest ultimate tensile strength and elongation at break (9.74 MPa and 45.73% respectively). Furthermore, results demonstrated that upon increasing PEG and Gly contents, degradability and hydrophilicity of the films increased whereas water uptake decreased. Water vapor transmission rate of the films was close to the range of 530–1200 g/m2d, indicating that the as formed films are possible candidates for dressing low exudate wounds or burns. Minocycline loaded films exhibited a biphasic drug release profile and it was more effective on gram-positive bacteria than on gram-negative bacteria. The polymeric film with the highest amount of loaded drug (2%) exhibited insignificant cytotoxicity (88%) against normal fibroblast cell line.  相似文献   
6.
Lithium fluoride powder (LiF) is a white powder with a density of 2.64 gr/cm3 and a melting point of 848°C. This powder has several applications such as flux, glaze, soldering, and aluminum melting process, but one of the most important uses of this powder is its application in dosimetry. The commercial powders currently used for this purpose have average sizes of 5 to 10 micrometers; the objective of this research is to produce LiF powder with nano-metric particle size. In this study, the reaction of LiOH + HF → LiF + H2O has been selected from among several reactions that were able to produce LiF powder, and some precipitation parameters such as temperature, time, agitation type, and supersaturation degree have been controlled. The morphology, phase analysis, and particle size distribution of the resulting powders were analyzed by SEM, XRD, and LPSA. Finally, lithium fluoride nano-powder was synthesized at a temperature of 25°C, pH about 2-3, reaction time less than 1 s, and agitation by ultrasonic bath.  相似文献   
7.
Advanced forms of hydrogels have many inherently desirable properties and can be designed with different structures and functions. In particular, bioresponsive multifunctional hydrogels can carry out sophisticated biological functions. These include in situ single-cell approaches, capturing, analysis, and release of living cells, biomimetics of cell, tissue, and tumor-specific niches. They can allow in vivo cell manipulation and act as novel drug delivery systems, allowing diagnostic, therapeutic, vaccination, and immunotherapy methods. In the present review of multitasking hydrogels, new approaches and devices classified into point-of-care testing (POCT), microarrays, single-cell/rare cell approaches, artificial membranes, biomimetic modeling systems, nanodoctors, and microneedle patches are summarized. The potentials and application of each format are critically discussed, and some limitations are highlighted. Finally, how hydrogels can enable an “all-in-one platform” to play a key role in cancer therapy, regenerative medicine, and the treatment of inflammatory, degenerative, genetic, and metabolic diseases is being looked forward to.  相似文献   
8.
This paper investigates the problem of decentralized model reference adaptive control (MRAC) for a class of large scale interconnected systems with both state and input delays. The upper bounds of the interconnection terms are considered to be unknown. Time varying delays in the nonlinear interconnection terms are bounded and nonnegative continuous functions and their derivatives are not necessarily less than one. For exact prediction, a decentralized adaptive state observer is designed and a nested predictor based approach is established to predict the future states of the input delay compensation. It is shown that the solutions of uncertain large‐scale time‐delay interconnected systems converge uniformly exponentially to a desired small ball. The effectiveness of the proposed approaches is illustrated by two examples.  相似文献   
9.
ABSTRACT

The physical properties of a snowpack strongly influence the emissions from the substratum, making snow property retrievals feasible by means of the surface brightness temperature observed by passive microwave sensors. Depending on the spatial resolution observed, time series records of daily snow coverage and critical snowpack properties such as snow depth (SD) and snow water equivalent (SWE) could be helpful in applications ranging from modelling snow variations for water resources management in a catchment to global climatologic studies. However, the challenge of including spaceborne SWE products in operational hydrological and hydroclimate modelling applications is very demanding with limited uptake by these systems, mostly attributed to insufficient SWE estimation accuracy. The root causes of this challenge include the coarse spatial resolution of passive microwave (PM) observations that observe highly aggregated snowpack properties at the spaceborne scale, and inadequacies during the retrieval process caused by uncertainties with the forward emission modelling of snow and challenges to find robust parameterizations of the models. While the spatial resolution problem is largely in the realm of engineering design and constrained by physical restrictions, a better understanding of developed and adopted retrieval methodologies can provide the clarity needed to enhance our knowledge in this field. In this paper, we review snow depth and SWE retrieval methods using PM observations, taking only dry snow retrieval processes into consideration. Snow properties using PM observations can be modelled by purely empirical relations based on underlying physical processes, and SD and SWE can be estimated by regression-based approaches. Snow property retrievals have been refined gradually throughout four decades use of PM observations in tandem with better understanding of physical processes, inclusion of better snowpack parameterizations, improved uncertainty analysis frameworks, and applying better inversion algorithms. Studying available methods, we conclude that snowpack parameterization is key to accurate retrieval. By improving retrieval algorithm architectures to better capture dynamic snowpack evolution processes, SWE estimates are likely to improve. We conclude that this challenge can be addressed by coupling emission models and land surface models or integrating weather-driven snowpack evolution into emission models and performing inversion in a Bayesian framework.  相似文献   
10.
One of the recurring questions in designing dynamic control environments is whether providing more information leads to better operational decisions. The idea of having every piece of information is increasingly tempting (and in safety critical domains often mandatory) but has become a potential obstacle for designers and operators. The present research study examined this challenge of appropriate information design and usability within a railway control setting. A laboratory study was conducted to investigate the presentation of different levels of information (taken from data processing framework, Dadashi et al. in Ergonomics 57(3):387–402, 2014) and the association with, and potential prediction of, the performance of a human operator when completing a cognitively demanding problem-solving scenario within railways. Results indicated that presenting users only with information corresponding to their cognitive task, and in the absence of other, non task-relevant information, improves the performance of their problem-solving/alarm handling. Knowing the key features of interest to various agents (machine or human) and using the data processing framework to guide the optimal level of information required by each of these agents could potentially lead to safer and more usable designs.  相似文献   
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