Superradiant Emission from Coherent Excitons in van Der Waals Heterostructures

Recent advancements in isolation and stacking of layered van der Waals materials have created an unprecedented paradigm for demonstrating varieties of 2D quantum materials. Rationally designed van der Waals heterostructures composed of monolayer transition-metal dichalcogenides (TMDs) and few-layer hBN show several unique optoelectronic features driven by correlations. However, entangled superradiant excitonic species in such systems have not been observed before. In this report, it is demonstrated that strong suppression of phonon population at low temperature results in a formation of a coherent excitonic-dipoles ensemble in the heterostructure, and the collective oscillation of those dipoles stimulates a robust phase synchronized ultra-narrow band superradiant emission even at extremely low pumping intensity. Such emitters are in high demand for a multitude of applications, including fundamental research on many-body correlations and other state-of-the-art technologies. This timely demonstration paves the way for further exploration of ultralow-threshold quantum-emitting devices with unmatched design freedom and spectral tunability.     

Investigation of the changes in physical properties of PES/PVC fabrics after aging

The aim of this work was to investigate the physical and mechanical performance of architectural polyester (PES)–poly(vinyl chloride) (PVC) membranes exposed to different artificial aging conditions. Two commercially available architectural membranes were chosen as research objects. The durability of the PES/PVC fabrics was evaluated by the loss in mechanical performance, scanning electron microscopy, and X-ray diffraction analysis in order to understand the effect of the degradation agents on the surface of the membranes. The mechanical performance of the PES/PVC membranes was unchanged. Scanning electron microscopy images of the tested materials showed initial cracks after aging. The X-ray fluorescence analysis showed that at the time of aging, the amount of Cl and Si decreased slightly, while Ti decreased by half, and Ca by volume increased twice. © 2019 Wiley Periodicals, Inc. J. Appl. Polym. Sci. 2019 , 136, 47523.     

Application of Non-Destructive Testing for Condition Analysis,Repair of Damages and Integrity Assessment of Vital Steel Structures

Russian Journal of Nondestructive Testing - Loads at vital steel structures occur during their production and assembly (residual stresses), during the execution of functional tasks in exploitation...     

Transmittance Measurements in Non-alternating Magnetic Field as Reliable Method for Determining of Heating Properties of Phosphate and Phosphonate Coated Fe3O4 Magnetic Nanoparticles

Different phosphates and phosphonates have shown excellent coating ability toward magnetic nanoparticles, improving their stability and biocompatibility which enables their biomedical application. The magnetic hyperthermia efficiency of phosphates (IDP and IHP) and phosphonates (MDP and HEDP) coated Fe₃O₄ magnetic nanoparticles (MNPs) were evaluated in an alternating magnetic field. For a deeper understanding of hyperthermia, the behavior of investigated MNPs in the non-alternating magnetic field was monitored by measuring the transparency of the sample. To investigate their theranostic potential coated Fe₃O₄-MNPs were radiolabeled with radionuclide ¹⁷⁷Lu. Phosphate coated MNPs were radiolabeled in high radiolabeling yield (>?99%) while phosphonate coated MNPs reached maximum radiolabeling yield of 78%. Regardless lower radiolabeling yield both radiolabeled phosphonate MNPs may be further purified reaching radiochemical purity of more than 95%. In vitro stabile radiolabeled nanoparticles in saline and HSA were obtained. The high heating ability of phosphates and phosphonates coated MNPs as sine qua non for efficient in vivo hyperthermia treatment and satisfactory radiolabeling yield justifies their further research in order to develop new theranostic agents.

     

A Dual Inhibitor of DYRK1A and GSK3β for β-Cell Proliferation: Aminopyrazine Derivative GNF4877

Loss of β-cell mass and function can lead to insufficient insulin levels and ultimately to hyperglycemia and diabetes mellitus. The mainstream treatment approach involves regulation of insulin levels; however, approaches intended to increase β-cell mass are less developed. Promoting β-cell proliferation with low-molecular-weight inhibitors of dual-specificity tyrosine-regulated kinase 1A (DYRK1A) offers the potential to treat diabetes with oral therapies by restoring β-cell mass, insulin content and glycemic control. GNF4877, a potent dual inhibitor of DYRK1A and glycogen synthase kinase 3β (GSK3β) was previously reported to induce primary human β-cell proliferation in vitro and in vivo. Herein, we describe the lead optimization that lead to the identification of GNF4877 from an aminopyrazine hit identified in a phenotypic high-throughput screening campaign measuring β-cell proliferation.     

方腔内耦合传热传质非对称流动数值模拟

对带有质热源的方腔内流体传热传质进行数值研究。针对不同Ra、Nc、Sr和Df，探究对称方腔内流体传热传质的分岔特性。结果表明：存在临界Ra_c使流体流动形态发生转变，当Ra<Ra_c时，流体流线、温度场和浓度场对称分布；当Ra>Ra_c时，流体发生偏斜。增大浮升力，流体更易发生分岔现象。增强Soret和Dufour效应可增强传热对称性并增大流体发生分岔的临界Rayleigh数。     

汽车悬架球头拉杆冷成形技术

为提高生产效率、改变原来通过车削加工汽车悬架球头拉杆的方式,提出了一种球头拉杆的多工位冷镦成形工艺。基于DEFORM-3D软件建立了有限元模型,对球头拉杆的塑性成形过程进行了仿真,研究了预成形凸模入模角α、预成形凹模圆角R1、终成形凹模圆角R2以及终成形凹模入模角β等工艺参数对球头拉杆成形的影响,并进行了正交试验,以模具在球头拉杆成形过程中所受载荷及工件损伤值为优化目标,获得了合理的工艺参数组合。结果表明:在保证工件成形质量及模具寿命的前提下,当预成形凸模入模角α为30°、预成形凹模圆角R1为12 mm、终成形凹模圆角R2为3 mm、终成形凹模入模角β为60°时,模具载荷及工件损伤有显著的降低。采用优化后的参数进行试模生产,工件成形质量较好,验证了模拟结果的可信性,能够有效地指导工艺设计人员的设计工作。