Hydroxyl Group Separation Distances in Anti-Freeze Compounds and Their Effects on Ice Nucleation

Since the discovery of biological antifreeze glycoproteins (AFGPs), which can inhibit ice nucleation, there has been considerable interest in understanding their mechanisms and mimicking them in synthetic polymers. In this study, we used molecular dynamics simulations of modified polyvinyl alcohol (PVA) compounds to show that the hydroxyl (OH) group distance is a key factor in whether certain compounds promote or inhibit ice nucleation. A hydroxyl distance smaller than ~2.8 Å but greater than ~7.1 Å in modified PVA (MPVA) compounds was associated with the promotion of ice nucleation, while a hydroxyl group separation distance of approximately ~5.0 Å was correlated with a delay in ice nucleation, owing to changes in the energy of the system. Thus, these results may help explain some of the mechanisms of current known anti-freeze compounds and may have implications for designing new anti-freeze compounds in the future.     

Effect of nitrogen on the antibacterial behavior of oxynitride glasses

The main drawback of bioglasses is their restricted use in load bearing applications and the consequent need to develop stronger glassy materials. This has led to the consideration of oxynitride glasses for numerous biomedical applications. This paper investigated two different types of glasses at a constant cationic ratio, with and without nitrogen (a N containing and a N-free glass composition) to better understand the effect of N on the biological properties of glasses. The results revealed that the addition of N increased the glass transition temperature, isoelectric point (IEP) and slightly increased wettability. Moreover, compared to N including glass, N-free glass exhibited better anti-bacterial activity against Escherichia coli (E. coli) and Staphylococcus aureus (S. aureus), two key bacteria that infect implants. In summary, these in vitro results indicated that amine functional groups existing in N containing glasses which are missing in N-free glasses, caused a slight difference in wetting behavior and a more obvious change in isoelectric point and in bacterial response. N-free glasses exhibited better inhibitory results both against E. coli and S. aureus compared to N including glass suggesting that oxygen rich glasses should be further studied for their novel antibacterial properties.     

Evaluation of the FEH Rainfall-Runoff Method for Catchments in the UK

The Flood Estimation Handbook, which was published in 1999, has substantially replaced the Flood Studies Report for design flood estimation in the UK. Although there are substantial differences between the handbook and the report, the philosophy of the rainfall-runoff method has been retained in the handbook. However, there are differences in the equations that have been used to estimate parameters of the rainfall-runoff method.
This paper provides a comprehensive evaluation of the performance of the Flood Estimation Handbook rainfall-runoff method for flood-frequency estimation, using data from eighty-eight catchments in the UK. The performance is evaluated by reference to the flood quantiles obtained from single-site frequency analysis, and comparison is made with the performance of the Flood Studies Report methodology. In general terms, the handbook over-estimates flood quantiles, with respect to (a) those estimated from observed records and (b) the report's quantiles. The paper explores the causes of these over-estimations and seeks linkages with particular catchment characteristics.     

Overheating in care settings: magnitude,causes, preparedness and remedies

ABSTRACT

Research in UK and elsewhere has highlighted that older people are particularly vulnerable to negative health effects of overheating. This paper examines the magnitude, causes, preparedness and remedies for addressing the risk of summertime overheating in four case study residential care and extra-care settings across the UK, spanning different building types, construction and age. An interdisciplinary approach is adopted, drawing from building science and social science methods, including temperature monitoring, building surveys, and interviews with design and management teams. The findings suggest that overheating is a current and prevalent risk in the case study schemes, yet currently little awareness or preparedness exists to implement suitable and long-term adaptation strategies (e.g., external shading). There was a perception from designers to managers, that cold represents a bigger threat to older occupants’ health than excessive heat. A lack of effective heat management was found across the case studies that included unwanted heat gains from the heating system, confusion in terms of responsibilities to manage indoor temperatures, and conflicts between window opening and occupant safety. Given that care settings should provide protection against risks from cold and hot weather, design, management and care practices need to become better focused towards this goal.     

Gardening cyberspace—social media and hybrid spaces in the creation of food citizenship in the Bristol city-region,UK

Abstract

This paper conducts a detailed analysis of urban food and online networks in Bristol, UK. In particular, it examines social media postings of grass-roots food networks. Qualitative research identifies and analyses five core themes, from which two dominant discourses emerge. Analysis reinforces the multifunctional nature of city food but moves beyond dominant scholarly pre-occupations with nutrition and physical resources. Instead, the paper positions social and symbolic aspects as equal components within the convening power of food. To date, social media has been neglected in urban food research, although this is a space as well-tended and structured as the physical spaces it augments. The paper finds a relationship of limited collaboration between the grass-roots networks and the city council. While the former are dynamic and networked, the council adheres to a linear policy process that limits the scope of citizenship. The relationships examined here indicate implications for urban planning processes.     

This land can sustain us: cooperative land use planning on the Oneida Reservation

Land use planning in indigenous communities often takes place within state-based planning initiatives, leaving indigenous governments to serve as token participants. Through these initiatives, state-based governments have the ability to wield their power and control the planning process to the detriment of indigenous governments. This study sets forth an alternative option involving cooperative land use planning practices where neither government controls the planning process. Drawing upon a case study of the Oneida Reservation in Wisconsin, USA, this study explores ways to increase cooperative land use planning relationships between indigenous and state-based governments. As one of the few empirical studies to apply critical planning theory to advocate for increased cooperative land use planning, this paper proposes a series of recommendations that can help indigenous and state-based governments avoid conflicts and work toward cooperative relationships.     

Evaluation of the effects of sodium chloride,potassium sorbate,nisin and lysozyme on the probability of growth of Clostridium sporogenes

The aim of this study was to evaluate the combined effect of salt (sodium chloride, 0–8% w/v), sorbate (potassium sorbate, 0–4.5% w/v), nisin (0–500 ppm) and lysozyme (0–500 ppm) on the survival of Clostridium sporogenes as a non‐toxigenic surrogate of Clostridium botulinum in terms of the probability of growth by using a central composite rotatable design. The results indicated that salt and sorbate were the most effective factors in preventing the growth of Cl. sporogenes in high‐moisture (>95%) and low‐acid conditions. The probability of growth of Cl. sporogenes in broth was reduced by combinations of salt and sorbate. Nisin and lysozyme had insignificant effects on the probability of growth of Cl. sporogenes (P > 0.05). Lysozyme individually and in combination with nisin had no inhibitory effect on Cl. sporogenes. Overall, the addition of sorbate and lysozyme may allow the salt concentration to be reduced while preventing growth.     

An APP roximate F-statistic

This note presents the properties of the numerator and denominator of an approximate F-statistic from an analysis of variance of the means in a two-way layout for random effects, with interaction, and unequal number of readings (n_ij ) per cell. As suspected an F-statistic results only if the n _ij are all equal, however the approximation should be good if the n _ij do not differ greatly or if n ^?1 _ij times the error variance is small relative to the variance of the interaction variable.     

Role of Bose enhancement in photoassociation

Abstract

We discuss the role of Bose enhancement of the dipole matrix element in photoassociation, using stimulated Raman adiabatic passage as an example. In a non-degenerate gas the time scale for coherent optical transients tends to infinity in the thermodynamic limit, whereas Bose enhancement keeps this time scale finite in a condensate. Coherent transients are therefore absent in photoassociation of a thermal non-degenerate gas, but are feasible if the gas is a condensate.     

Performative technologies for heritage site regeneration

Heritage sites are an important part of understanding our role in history. They have the potential to teach us important lessons, such as where we came from and subsequently, the people it has made us today. As members of a large, heritage-led, regeneration project, we are working with the Hafod–Morfa Copperworks, a heritage site in the Lower Swansea Valley where there is not much to see or hear. The few ruins at the site make it difficult to imagine what the site would have been like back in its heyday. Our goal at the site is to draw people together, not to view a finished piece of curated heritage, but rather, to start conversations about their memories and the significance of the site to them and to discover what they would like to see at the site in the future. The technology we are producing is about engaging with the local community and stakeholders as groups to provoke discussion. This contrasts with previous uses of mobile guides which only attempt to be tourist aids. In this article, we report on two prototype technologies we have developed to help accomplish this task. Throughout the article, we discuss how and why designing performative technologies could help encourage people to visit, socialise and communicate within the area. Our early results suggest that expressive performative technologies are good at gaining spectators’ attention and encouraging an active engagement between performer and spectator.