A 16-Mbit/s adapter chip for the IBM token-ring local area network

The authors describe a 9.02×9.02-mm chip built in 1-μm CMOS with two levels of metal and an additional mask level for fabricating capacitors. It contains both analog and digital circuits and has provisions for self-test. The function includes the transmitter, receiver, protocol handler, an microprocessor, as well as interfaces for RAM/ROM storage, IBM PC bus, IBM PS/2 bus, IBM 3174 bus, and Motorola 68000 bus. The physical design terrains are formed by 24K circuits of standard cell gates, a 10K-circuit equivalent hand-honed custom microprocessor, and an analog macro. The chip operates from a single 5-V supply, and the power consumption is 0.8 W nominal at 16 Mb/s. The chip can also be operated at 4 Mb/s     

Beyond the "Self in Self-Efficacy: Spouse Confidence Predicts Patient Survival Following Heart Failure.

Ratings of patient efficacy to manage illness, made by 191 congestive heart failure patients and their spouses, were examined as predictors of patients' survival over the next 4 years. When considered alone, both the patient's self-efficacy and the spouse's confidence ratings predicted survival, but only spouse confidence remained significant when both partners" efficacy ratings were included in the same Cox regression model. The overlapping prognostic significance of spouse confidence and a global, multicomponent measure of marital quality positioned the former as a proxy for the latter, reflecting a fundamentally social protective factor in patient survival. Successful adaptation to heart failure appears to involve more than the patient's personal agency, and psychosocial data from spouses can improve prediction of patient outcomes. (PsycINFO Database Record (c) 2010 APA, all rights reserved)     

Couples coping with congestive heart failure: Role and gender differences in psychological distress.

Psychological distress and marital quality were assessed with male (n=128) and female (n=49) congestive-heart-failure (CHF) patients and their spouses. Hopkins Symptom Check List-25 scores were in the distressed range for 57% of patients and 40% of spouses. This role difference was greater for men than for women, and a gender difference (more distress in women than men) was greater for spouses than for patients. The patient's distress, but not the spouse's, reflected the severity of the patient's illness, and distress for both partners correlated negatively with ratings of marital quality. Female-patient couples reported better relationship quality than male-patient couples, however, and a mediation analysis indicated that the gender difference in spouse distress could be explained by marital quality. Results highlight the contextual nature of CHF distress and suggest that role differences in distress vary by gender. (PsycINFO Database Record (c) 2010 APA, all rights reserved)     

Husbands' and wives' alcohol use disorders and marital interactions as longitudinal predictors of marital adjustment.

In this longitudinal study, the relationships among wives' and husbands' lifetime alcoholism status, marital behaviors, and marital adjustment were tested. Participants were 105 couples from the Michigan Longitudinal Study (MLS), an ongoing multimethod investigation of substance use in a community-based sample of alcoholics, nonalcoholics, and their families. At baseline (T1), husbands and wives completed a series of diagnostic measures, and lifetime diagnosis of alcohol use disorder (AUD, as defined in the Diagnostic and Statistical Manual of Mental Disorders, 4th ed.), was assessed. Couples completed a problem-solving marital interaction task 3 years later at T2, which was coded for the ratio of positive to negative behaviors. Couples also completed a measure of marital adjustment at T4 (9 years after T1 and 6 years after T2). Results showed that husbands' lifetime AUD predicted lower levels of their wife's positive marital behaviors 3 years later but was not related to their own or their wife's marital adjustment 9 years from baseline. By contrast, wives' lifetime AUD had direct negative associations with their own and their husband's marital satisfaction 9 years later, and wives' marital behaviors during the problem-solving task predicted their own and their husband's marital satisfaction 6 years later. Findings indicate that marital adjustment in alcoholic couples may be driven more by the wives' than the husbands' AUD and marital behavior. Implications for intervention with alcoholic couples were discussed. (PsycINFO Database Record (c) 2010 APA, all rights reserved)     

Shaky foundations of hierarchical biological materials

It is popular stance that successful growth – be it structural, economic or biological – requires a stable foundation. The hierarchical structure of native biological materials and tissues introduces variations in form and function across a multitude of scales. Yet, many synthetic scaffolds and substrates in which such materials are assembled, the foundation, are designed at a single scale. The result is an uncertain or shaky foundation for material assembly and tissue growth, where changes in the scaffold properties and architecture result in unpredictable behaviors in tissue development, and proven, reliable scaffolds for one tissue type may be completely unsuitable for another. This is in contrast to the behavior of foundations for civil engineering structures, which provide a decoupling of the foundation from the building design since different foundations can support equivalent functional structures. Current advancements in the design of biologically active foundations shed light on proven scaffolds and substrates, but cannot be used to design and predict success from the bottom-up. This is because while the phenomenological coupling between materials and substrates has been well investigated and has yielded methodologies for biomaterial synthesis, the underlying mechanisms of self-assembly and growth are not fully understood. A potential solution lies in the utilization of hierarchical material foundations, with molecular, fibrillar and other interactions designed across all length- and time-scales with engineered, predictive, and repeatable outcomes. The potential to realize such hierarchical multiscale scaffolds can be found in the exploitation of responsive, or mutable, polymer systems that exhibit precise control and variegated chemical functionalities for applications in diverse areas such as regenerative medicine, cancer treatment or drug delivery.     

Effects of contralateral speech competition on auditory event-related potentials recorded from elderly listeners: brain map study

Topographic brain mapping was used to investigate the ability of young and elderly female listeners to attend to tones at one ear in the presence of speech competition at the opposite ear. An oddball stimulus presentation paradigm was used to record the N1, P2, and P300 components of the late auditory evoked potential from 19 scalp locations. With speech competition, elderly listeners exhibited significantly larger reductions in N1 amplitude than did young listeners. This suggests that N1 may provide an electrophysiologic index of age-related breakdowns in processing sounds in the presence of background competition. An unexpected difference was also found between young and elderly listeners in P300 scalp topography. While the young listeners' P300 response was centered at midline for both left and right ear stimulation, the elderly participants had P300 maxima centered in the parietal area of the hemisphere located contralateral to the test ear. This suggests that some of the functional properties (e.g., timing, strength, orientation) of the P300 neural generators may change with age or, alternatively, that different generators may be operative in elderly listeners.     

Auditory masking-level differences in the cat.

Trained 4 cats to avoid shock by responding to the intermittent occurrence of 1-kHz tone pulses at one ear, while a continual train of noise pulses was simultaneously presented either to the signal ear alone or to both ears. Using the masked threshold levels determined with monaural noise as a reference, the amount of unmasking produced by the addition of noise to the nonsignal ear was measured. Significantly lower tonal detection thresholds were observed when noise equal in intensity to that at the signal ear was added to the nonsignal ear. Additional unmasking occurred when the intensity of the noise at the latter ear was raised to a level 10 db higher than that at the signal ear. (PsycINFO Database Record (c) 2010 APA, all rights reserved)     

Compliant threads maximize spider silk connection strength and toughness

Millions of years of evolution have adapted spider webs to achieve a range of functionalities, including the well-known capture of prey, with efficient use of material. One feature that has escaped extensive investigation is the silk-on-silk connection joints within spider webs, particularly from a structural mechanics perspective. We report a joint theoretical and computational analysis of an idealized silk-on-silk fibre junction. By modifying the theory of multiple peeling, we quantitatively compare the performance of the system while systematically increasing the rigidity of the anchor thread, by both scaling the stress–strain response and the introduction of an applied pre-strain. The results of our study indicate that compliance is a virtue—the more extensible the anchorage, the tougher and stronger the connection becomes. In consideration of the theoretical model, in comparison with rigid substrates, a compliant anchorage enormously increases the effective adhesion strength (work required to detach), independent of the adhered thread itself, attributed to a nonlinear alignment between thread and anchor (contact peeling angle). The results can direct novel engineering design principles to achieve possible load transfer from compliant fibre-to-fibre anchorages, be they silk-on-silk or another, as-yet undeveloped, system.     

Lagrangian finite element treatment of transient vibration/acoustics of biosolids immersed in fluids

Superposition principle is used to separate the incident acoustic wave from the scattered and radiated waves in a displacement‐based finite element model. An absorbing boundary condition is applied to the perturbation part of the displacement. Linear constitutive equation allows for inhomogeneous, anisotropic materials, both fluids and solids. Displacement‐based finite elements are used for all materials in the computational volume. Robust performance for materials with limited compressibility is achieved using assumed‐strain nodally integrated simplex elements or incompatible‐mode brick elements. A centered‐difference time‐stepping algorithm is formulated to handle general damping accurately and efficiently. Verification problems (response of empty steel cylinder immersed in water to a step plane wave, and scattering of harmonic plane waves from an elastic sphere) are discussed for assumed‐strain simplex and for voxel‐based brick finite element models. A voxel‐based modeling scheme for complex biological geometries is described, and two illustrative results are presented from the bioacoustics application domain: reception of sound by the human ear and simulation of biosonar in beaked whales. Copyright © 2007 John Wiley & Sons, Ltd.