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1.
A neural-deterministic simulation model applied for calculating distributions of temperatures and moisture content in a bed of wheat stored in a steel silo without aeration is presented in the article. The model consists of differential equations of heat and moisture transfer, initial and boundary conditions, and three artificial neural networks used during simulated ambient air conditions. Experiments and computer simulations were carried out in order to determine temperature fields in wheat grain stored in a steel silo for two months. The computer simulations were carried using MATLAB and FEMLAB software. The difference between measured and simulated temperature in grain near the silo wall at a height of 2.5 m from the bottom was less than 3.0°C. On the basis of the analysis performed it was concluded that the temperature distributions obtained with the model were consistent with the measured results obtained for grain stored in a steel silo without aeration.  相似文献   
2.
Primary open-angle glaucoma (POAG) constitutes the most common type of glaucoma. Emerging evidence suggests that Endoplasmic Reticulum (ER) stress and the protein kinase RNA-like endoplasmic reticulum kinase (PERK)-mediated Unfolded Protein Response (UPR) signaling pathway play a key role in POAG pathogenesis. Thus, the main aim of the study was to evaluate the effectiveness of the PERK inhibitor LDN-0060609 in cellular model of glaucoma using primary human trabecular meshwork (HTM) cells. To evaluate the level of the ER stress marker proteins, Western blotting and TaqMan gene expression assay were used. The cytotoxicity was measured by XTT, LDH assays and Giemsa staining, whereas genotoxicity via comet assay. Changes in cell morphology were assessed by phase-contrast microscopy. Analysis of apoptosis was performed by caspase-3 assay and flow cytometry (FC), whereas cell cycle progression by FC. The results obtained have demonstrated that LDN-0060609 triggered a significant decrease of ER stress marker proteins within HTM cells with induced ER stress conditions. Moreover, LDN-0060609 effectively increased viability, reduced DNA damage, increased proliferation, restored normal morphology, reduced apoptosis and restored normal cell cycle distribution of HTM cells with induced ER stress conditions. Thereby, PERK inhibitors, such as LDN-0060609, may provide an innovative, ground-breaking treatment strategy against POAG.  相似文献   
3.
The paper is focused on identifying error sources in computational fluid dynamics(CFD) predictions of a spray drying process. Seven groups of drying and atomisation parameters were selected for analysis and 13 simulation trials were performed. The theoretical results were compared with experimental data and sensitivity of the simulation results to the analysed factors was determined. The following parameters affecting the accuracy of CFD spray modelling were found: gas turbulence model, particle dispersion, atomising air, initial parameters of atomisation and heat losses to the environment. A major difference in the errors committed during modelling of spray drying process for fine and coarse sprays was observed.  相似文献   
4.
The thermal cracking and catalytic cracking processes of low-density polyethylene were studied in a closed autoclave. The compositions of gaseous and liquid products were analysed by means of GC/FID and GS/MS chromatographic methods. The fractional composition of liquid products was found by distillation. Increased temperature of PE depolymerisation process increases the production of gaseous products and low-boiling liquid compounds; more aromatic hydrocarbons are formed instead of alkenes. When a lower temperature and longer time are adopted for the process to reach the assumed conversion, more straight chained hydrocarbons are produced. The acidic aluminosilicate catalyst yields more low-boiling liquid fractions, more isoalkanes and more aromatics. The neutral alumina is favourable for the production of alkenes and vacuum gas oil fraction in comparison to a non-catalytic process. The Ni–Mo/Al2O3 catalyst is efficient in hydrogenation of depolymerisation products. The reaction products contain only saturated compounds then and no aromatics are formed.  相似文献   
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ABSTRACT

We report a successful growth of the ZnMgHf F-type icosahedral quasicrystal in the form of faceted single grains. By varying the heat treatment parameters we were able to obtain single crystals with a quality suitable for a single crystal X-ray diffraction which was conducted in a synchrotron facility. Ab initio structure solution by a charge flipping algorithm manifests the existence of two types of Bergman clusters. Clusters are differentiated by the preferential occupation of the high-symmetry positions by hafnium in a rhombic triacontahedron, being the outer shell of the atomic cluster.

This paper is part of a Thematic Issue on The Crystallographic Aspects of Metallic Alloys.  相似文献   
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This paper reports on work aimed at designing a dynamic system-level simulator for wireless telecommunication networks. Presented here are considerations devoted to the development of a software tool, a preliminary condition for the analysis of various technological aspects directed towards the enhancement of WCDMA (Wideband Code Division Multiple Access) technology by implementing SON (Self Organized Networks) functionality. The future broadening of such strategies to include multi-technology networks will be possible with the created methodology and software library. Compared to typical attempts in this research domain, which involve pure software representations of wireless system operations, the methodology offered in this paper creates a tool that has direct practical value, which is primarily based on operations on input data measured in an actual wireless telecommunications system. Thus, both detailed cases concerning wireless communication in a chosen region of the world and general ideas of a conceptual nature can be considered with the support of an IRSON (Integrated Research on SON) system-level simulator.  相似文献   
9.
Liquid natural gas (LNG) delivered by means of sea-ships is compressed and then evaporated before its introduction to the system of pipelines. The possibilities of the utilization of cryogenic exergy of LNG for electricity production without any additional combustion of any its portion, have been analyzed. Three variants of the plant have been investigated. A cascade system with two working fluids has been analyzed in two first of them. The economic optimization proved that the optimum temperature difference in the LNG evaporation is higher than initially assumed. Therefore, a third variant of the plant has been analyzed, with ethane as a single working fluid. Only the third variant has been analyzed in detail.  相似文献   
10.
The goal of the study was to determine the influence of drying shrinkage on the kinetics of convection apple slab drying. The arbitrary Lagrange-Eulerian (ALE) method was used to enter a problem with moving boundaries. It was found that drying shrinkage had a major influence on the both simulated temperature and water content in the material. The lower the moisture content in particles during drying, the more pronounced the effect of shrinkage on simulation of heat and mass transfer. It was found that application of the arbitrary Lagrange-Eulerian method for shrinkage modeling leads to a relatively simple mathematical model of the drying kinetics of shrinkable materials.  相似文献   
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