Effect of the functional group of polyethylene glycol on the characteristics of copper pillars obtained by electroplating

Journal of Materials Science: Materials in Electronics - Five polyethylene glycol (PEG)-based compounds with varying terminal functional groups were investigated as suppressors to investigate the...     

Caffeic Acid Phenethyl Ester Suppresses Proliferation and Survival of TW2.6 Human Oral Cancer Cells via Inhibition of Akt Signaling

Caffeic acid phenethyl ester (CAPE) is a bioactive component extracted from honeybee hive propolis. Our observations indicated that CAPE treatment suppressed cell proliferation and colony formation of TW2.6 human oral squamous cell carcinoma (OSCC) cells dose-dependently. CAPE treatment decreased G1 phase cell population, increased G2/M phase cell population, and induced apoptosis in TW2.6 cells. Treatment with CAPE decreased protein abundance of Akt, Akt1, Akt2, Akt3, phospho-Akt Ser473, phospho-Akt Thr 308, GSK3β, FOXO1, FOXO3a, phospho-FOXO1 Thr24, phospho-FoxO3a Thr32, NF-κB, phospho-NF-κB Ser536, Rb, phospho-Rb Ser807/811, Skp2, and cyclin D1, but increased cell cycle inhibitor p27^Kip. Overexpression of Akt1 or Akt2 in TW2.6 cells rescued growth inhibition caused by CAPE treatment. Co-treating TW2.6 cells with CAPE and 5-fluorouracil, a commonly used chemotherapeutic drug for oral cancers, exhibited additive cell proliferation inhibition. Our study suggested that administration of CAPE is a potential adjuvant therapy for patients with OSCC oral cancer.     

Heuristic and integrated approach for technical document authority and authentication sequence determination

Currently, the information and Internet technologies are widely used in modern organizations. Under the trend toward e-manufacturing, most technical knowledge, documents and information are transformed from paper-based into electronic formats. In order to improve the efficiency of document security and authentication process management, this paper proposes a heuristic two-phase model for authority and authentication sequence determination for technical documents. In Phase 1 (i.e. authority determination), the keyword extraction and document categorization rules are incorporated into the authority reasoning algorithm to emphasize the importance of technical document contents. In Phase 2, according to the authority reasoning result, six content- and reviewer-oriented indices are proposed for authentication sequence determination. Based on the reasoning models, an integrated prototype system is developed and a demonstration case is also provided to validate the effectiveness of the methodologies. The model and technique explored in this research can be used as the kernel for technical document management and exchange under the computer-integrated manufacturing environment.     

An efficient reversible data hiding method for AMBTC compressed images

Multimedia Tools and Applications - Analyzing multimedia data in mobile devices is often constrained by limited computing capacity and power storage. Therefore, more and more studies are trying to...