Colour Doppler energy (power) mode ultrasound

During the study period, 24,492 pregnant women attended the Harris Birthright Research Centre at 10-14 weeks of gestation, at which time, in addition to the measurements of nuchal translucency thickness and crown-rump length (CRL), data on fetal abnormalities were recorded onto a computer database. Cases of megacystis were identified and the records were reviewed. Additionally, the relationship of the longitudinal bladder diameter with the CRL and the bladder diameter/CRL ratio (expressed as a percentage) were examined with the use of data from 300 normal fetuses at 10-14 weeks. Megacystis was present in 15 of the 24,492 pregnancies (1 in 1,633) and in these cases the minimum longitudinal bladder diameter was 8 mm and the minimum bladder diameter/CRL ratio was 13%. In the 300 control fetuses the bladder was visualized in 278 (92.7%) of the cases and the longitudinal bladder diameter increased with the CRL (bladder diameter = 0.065 x CRL - 0.69; r = 0.47, p < 0.001), none of the measurements was more than 6 mm and the median bladder diameter/CRL ratio was 5.4% (range 0-10.4%) which did not change significantly with gestation (r = 0.1, p = 0.09). The bladder was visible in all cases with a minimum CRL of 67 mm. In three of the 15 cases with megacystis, there were chromosomal abnormalities. In the chromosomally normal group, there were seven cases with spontaneous resolution, whereas in four cases there was progression to severe obstructive uropathy. The bladder diameter was 8-12 mm and the bladder diameter/CRL ratio 13-22% in all cases with resolution and in one case with progressive megacystis; in the other three cases with progressive obstruction, the bladder length was more than 16 mm and the bladder diameter/CRL ratio was more than 28%.     

A randomized, double-blind, placebo-controlled, crossover study to assess the immediate effect of sublingual glyceryl trinitrate on the ankle brachial pressure index, claudication, and maximum walking distance of patients with intermittent claudication

The conventional method of identifying acaricide resistance in a suspect tick population by the United Nations Food and Agriculture Organization packet assay is a laborious and time-consuming process. DNA probes have been demonstrated as rapid and accurate tools for detecting pesticide resistance in insect species. Random-amplified polymorphic DNA (RAPD) has been used by other groups to differentiate species of mosquitoes and populations within a mosquito species. By using different arbitrary oligonucleotides as primers with RAPD, we have demonstrated that various strains of Boophilus microplus (Canestrini) show different patterns of DNA fragments on agarose gel electrophoresis. The unique DNA fragments may be useful for developing probes that can detect acaricide resistance in field pest populations.     

Improving the accuracy and efficiency of junction capacitance characterization: strategies for probing configuration and data set size

In this paper, the on-wafer measurement of junction depletion capacitance is examined. This work provides an in-depth discussion of possible probing configurations which can be used. It outlines a method to consistently measure the junction capacitances accurately. The results from this method compare favorably with those extracted using S-parameter measurements. Additionally, methods are formulated to reduce the number of data points required for parameter extraction while at the same time maintaining a high model accuracy.     

A SPICE compatible subcircuit model for lateral bipolar transistorsin a CMOS process

This paper describes a SPICE compatible subcircuit model of a lateral pnp transistor, which was fabricated in a 0.6 μm CMOS process. The extraction of a dc parameter set for the lateral device is more complicated than for a vertical device because of the presence of two parasitic vertical bipolar transistors which are formed by the emitter/collector, the base and the substrate regions. The SPICE Gummel-Poon model does not predict the substrate current accurately. This paper proposes a method which involves the use of a subcircuit incorporating three SPICE Gummel-Poon models [representing one lateral and two parasitic vertical bipolar junction transistors (BJT's)]. The development of this model, its implementation and the results obtained are outlined and discussed. This circuit model is SPICE compatible and can thus be used in commercial simulators. The model provides good agreement over a wide range of measured dc data including substrate current prediction