Optimum receiver design for OFDM-based broadband transmission .II.A case study

This paper details on the design of OFDM receivers. Special attention is paid to the OFDM-specific receiver functions necessary to demodulate the received signal and deliver soft information to the outer receiver for decoding. In part I of the paper, the effects of nonideal transmission conditions have been thoroughly analyzed. To show the impact of the synchronization algorithms-which are most critical in OFDM-on system performance and complexity we consider the design of a complete receiver consisting of symbol synchronization, carrier/sampling clock synchronization and channel estimation. The performance of the algorithms is analyzed and a qualitative estimate of the resulting complexity is given. This allows one to draw conclusions concerning the achievable system performance under realistic complexity assumptions     

Channel tracking for RAKE receivers in closely spaced multipathenvironments

This paper deals with the problem of channel tracking for RAKE receivers in propagation environments characterized by closely spaced multipath components. After outlining why conventional single-path channel tracking algorithms fail in such scenarios, several new estimation algorithms are developed that are tailored to channels with closely spaced multipaths. This is achieved by removing or minimizing self-interference caused by multipath components. Other interfering users are treated as noise. Both timing tracking and phasor tracking and their interaction are covered in this paper. The derived algorithms are benchmarked against perfect channel knowledge on one hand and conventional tracking algorithms on the other hand, both in a UMTS test scenario. In moderate scenarios, the use of these new algorithms leads to performance improvements of up to 2 dB, in terms of signal-to-noise ratio (SNR) at moderate bit error rates, and even manages to track the channel in conditions where conventional tracking algorithms fail completely     

Metachromatic leukodystrophy and coincidental finding of papillomatosis of the gallbladder. A case report

In this case report we describe the coincidental finding of polyps in the gallbladder by ultrasound investigation in a six-year-old girl, known to have metachromatic leukodystrophy. The investigation was carried out because of suspicion of abdominal trauma after falling down the stairs and finding elevated serum amylase.     

Achievable rate of MIMO channels with data-aided channel estimationand perfect interleaving

The achievable rate of a coherent coded modulation digital communication system with data-aided channel estimation and a discrete equiprobable symbol alphabet is derived under the assumption that the system operates on a flat fading multiple-input/multiple-output channel and uses a perfect interleaver to combat the bursty nature of the channel. It is shown that linear minimum mean square error channel estimation directly follows from the derivation and links average mutual information to the channel dynamics. Based on the assumption that known training symbols are transmitted, the achievable rate of the system is optimized with respect to the amount of training information needed     

An information theoretic foundation of synchronized detection

The constrained capacity of a coherent coded modulation (CM) digital communication system with data-aided channel estimation and a discrete, equiprobable symbol alphabet is derived under the assumption that the system operates on a flat fading channel and uses an interleaver to combat the bursty nature of the channel. It is shown that linear minimum mean square error channel estimation directly follows from the derivation and links average mutual information to the channel dynamics. Based on the assumption that known training symbols are transmitted, the achievable rate of the system is optimized with respect to the amount of training information needed. Furthermore, the results are compared to the additive white Gaussian noise channel, and the case when ideal channel state information is available at the receiver     

Optimum receiver design for wireless broad-band systems using OFDM.I

Orthogonal frequency-division multiplexing (OFDM) is the technique of choice in digital broad-band applications that must cope with highly dispersive transmission media at low receiver implementation cost. In this paper, we focus on the inner OFDM receiver and its functions necessary to demodulate the received signal and deliver soft information to the outer receiver for decoding. The effects of relevant nonideal transmission conditions are thoroughly analyzed: imperfect channel estimation, symbol frame offset, carrier and sampling clock frequency offset, time-selective fading, and critical analog components. Through an appropriate optimization criterion (signal-to-noise ratio loss), minimum requirements on each receiver synchronization function are systematically derived. An equivalent signal model encompassing the effects of all relevant imperfections is then formulated in a generalized framework. The paper concludes with an outline of synchronization strategies     

Roxatidine versus ranitidine in the treatment of duodenal ulcers: a randomized double-blind controlled multicentre study in Singapore

Roxatidine acetate, a new H2 receptor antagonist, was compared with ranitidine in the treatment of duodenal ulcers in a double-blind multicentre study. Eighty-four patients with endoscopically proven duodenal ulcer were randomized to receive 150 mg roxatidine acetate or 300 mg ranitidine at bedtime. Repeat endoscopy was performed after 4 weeks (25-33 days) and if the ulcer had not healed, another endoscopy was performed after a further 4 weeks of treatment. Using per protocol analysis 73.6% of ulcers treated with roxatidine healed at 4 weeks compared to 72.2% of ulcers treated with ranitidine (P = NS). The healing rates at 8 weeks were 92% with roxatidine and 83.3% with ranitidine (P = NS). Using equivalence tests, the healing rate of roxatidine was found to be equivalent to that of ranitidine within a 20% region. Roxatidine users took significantly less antacids than ranitidine users (P < 0.05). There were no significant adverse effects due to roxatidine or ranitidine. Roxatidine is a safe effective drug in the treatment of duodenal ulcers with a healing rate comparable to that of ranitidine.     

Helicobacter pylori infection and gastric emptying of indigestible solids in patients with dysmotility-like dyspepsia

BACKGROUND: The role of Helicobacter pylori and gastric motility in dysmotility-like dyspepsia is unclear. The aim of this study was to determine whether delayed gastric emptying of indigestible solids and H. pylori infection are associated with dysmotility-like dyspepsia. METHODS: Thirty-two healthy volunteers and 72 patients fulfilling the criteria of dysmotility-like dyspepsia received a gastric emptying test using radiopaque markers, and the H. pylori status was determined by histology. RESULTS: Twenty-seven percent of volunteers were H. pylori-positive, compared with 32% in the dyspeptic groups (P = NS). Gastric emptying was significantly slower in dyspeptic patients than controls and in H. pylori-positive patients than H. pylori-negative patients. Subjects with gastroparesis have a higher chance of developing dysmotility-like dyspepsia (odds ratio (OR), 2.5) than subjects with normal gastric emptying. Subjects with H. pylori and gastroparesis have an increased likelihood of developing dysmotility-like dyspepsia (OR, 4.3) than if either factor were present alone. CONCLUSION: Our data suggest that gastroparesis alone and gastroparesis and H. pylori infection are associated with dysmotility-like dyspepsia.