Synthesis of Self-Healing Bio-Based Tannic Acid-Based Methacrylates By Thermoreversible Diels–Alder Reaction

This investigation reports the effective use of the Diels–Alder (DA) click reaction in the preparation of self-healing bio-based dendritic methacrylates having reactive furfuryl functionality. Bio-based methacrylates were synthesized by modifying tannic acid with glycidyl methacrylate and furfuryl functionality was introduced by atom transfer radical polymerization with varied amount of furfuryl methacrylate monomer. The thermoreversible network was successfully achieved by DA and retro-DA reaction between the furfuryl groups and a bifunctional maleimide crosslinker, bismaleimide. This process was studied by nuclear magnetic resonance spectroscopy, Fourier transform infrared spectroscopy, thermogravimetric analysis, and solvent exposure tests. Differential scanning calorimetry analysis was used to determine the endothermic retro-DA reaction in the DA adduct. The self-healing property of the above crosslinked material was demonstrated by monitoring the repair of a scratch in the polymer film upon heating and cooling. This was analyzed by scanning electron microscopy. POLYM. ENG. SCI., 60:140–150, 2020. © 2019 Society of Plastics Engineers     

Multifunctional mussel-inspired Gelatin and Tannic acid-based hydrogel with pH-controllable release of vitamin B12

Hydrogels have emerged to be an impeccable material for a large variety of applications over the past few decades. In the field of biomedical applications, remarkable progress has been observed in the effort of fabricating numerous hydrogel systems. In this work, gelatin and tannic acid-based stretchable and adhesive hydrogel has been synthesized to study the release behavior of vitamin B₁₂. Successful formation of the synthesized hydrogels was confirmed by Fourier transform infrared and X-ray diffraction analysis. The morphology of the surfaces and the cross section of such hydrogels were studied with Scanning electron microscopy analysis. Swelling behavior of our hydrogel was studied with Design Expert software. The maximum swelling of the hydrogel was found to be around 137 g/g. Adhesive property was demonstrated on various surfaces to observe the adhesiveness of the fabricated hydrogel. Blood compatibility study was also performed. The release behavior of vitamin B₁₂ was performed in two different pH media and it was found to have enhanced value in the fluid mimicking the intestine. This work provides a new prospect for designing hydrogels with stretchable and adhesive properties with pH-controllable drug delivery applications along with other promising applications in various fields of research.     

On-chip thermopneumatic pressure for discrete drop pumping

A class of "lab-on-a-chip" devices use external air pressure for pumping discrete drops in a microchannel network. External air connectors can be cumbersome and are real-estate intensive. We have developed an on-chip technique to generate pressures required for metering and pumping of nanoliter-volume discrete drops. This is achieved by heating of trapped air in a pressure-generating chamber. The pressure-generating chamber is connected to the point of pressure application in the liquid-conveying microchannel through an air-delivery channel. The trapped air volume on the order of 100 nL is heated by resistive metal heaters by tens of degrees celcius to generate air pressures on the order of 7.5 kN/m2. The rate of discrete drop pumping is electronically controlled in the microchannel device by controlling the rate of air heating. Flow rates on the order of 20 nL/s are obtained in the microchannel (300 microns x 30 microns) by heating the air chamber at the rate of approximately 6 degrees C/s. In this paper, we describe the design, fabrication, and operation of this new technique of generating on-chip air pressure, used for metering and pumping nanoliter discrete drops in microchannels.     

Sparse regularization method for the detection and removal of random-valued impulse noise

In this paper, we propose a novel two-stage algorithm for the detection and removal of random-valued impulse noise using sparse representations. The main aim of the paper is to demonstrate the strength of image inpainting technique for the reconstruction of images corrupted by random-valued impulse noise at high noise densities. First, impulse locations are detected by applying the combination of sparse denoising and thresholding, based on sparse and overcomplete representations of the corrupted image. This stage optimally selects threshold values so that the sum of the number of false alarms and missed detections obtained at a particular noise level is the minimum. In the second stage, impulses, detected in the first stage, are considered as the missing pixels or holes and subsequently these holes are filled-up using an image inpainting method. Extensive simulation results on standard gray scale images show that the proposed method successfully removes random-valued impulse noise with better preservation of edges and other details compared to the existing techniques at high noise ratios.     

Development of self-healing star metallopolymers by metal–ligand crosslinking

The development of artificial materials with reversible and efficient self-healing property is an emerging and challenging task in intelligent materials science. In this article, we have developed a six-arm star copolymer system consisting of terpyridine moieties as end-chain functionality for the formation of self-healing metallopolymer networks. The star was synthesized using the atom transfer radical polymerization technique and subsequent crosslinking by the addition of iron (II) salts with three different counterions. The resulting materials exhibit promising self-healing performance as compared with a linear polymer system within time intervals of 6–8 h at moderate temperatures of 80–120 °C. © 2019 Wiley Periodicals, Inc. J. Appl. Polym. Sci. 2020 , 137, 48527.     

Microencapsulated self-healing polymers via controlled,surface initiated atom transfer radical polymerization from the surface of graphene oxide

Polymers were grown directly on the surface of graphene oxide (GO). The method involved the covalent attachment of an atom transfer radical polymerization (ATRP) initiator on the surface of GO followed by the polymerization of methylmethacrylate, styrene or t-butyl acrylate using it as the macroinitiator. The surface initiated poly(methylmethacrylate) (PMMA-IGO) was embedded with microcapsules containing glycidyl methacrylate (GMA) to introduce self-healing property. The polymeric chains grown on the surface of the GO exhibited self-healing behaviour on rupture of the microcapsules. These polymer chains on the surface of GO preserved living characteristics and was able to resume copolymerization with released GMA on rupture of the microcapsules and get infiltrated into the cracks. As a result, the cracked planes were covalently re-bonded, offering almost 92% recovery of strength.     

Biting behaviour and biting rhythm of potential Japanese encephalitis vectors in Assam

Studies on biting behaviour and biting cycles of medically important mosquitoes were carried out in Madhupur village and Tarajan tea estate of upper Assam. Collections were made off human baits outdoors and indoors and off cattle bait outdoors from August 1991 to July 1992. Human bait collections were performed using the 'stationary direct bait' technique. A total of 9,072 adult host seeking female mosquitoes representing 26 species and 5 genera were collected off baits of which 36.9% were collected off human baits and the rest from cattle. All mosquitoes were primarily zoophilic, although significant numbers were collected biting man outdoors. Biting preferences of important Japanese encephalitis (JE) vectors for man and cattle were studied using outdoor man:outdoor cattle ratio (attraction ratio = AR). Culex quinquefasciatus was attracted towards human baits the most (AR = 8.1:1), followed by Cx. bitaeniorhynchus (AR = 1.6:1) and Mansonia annulifera (AR = 1.3.1). The hourly biting activity of important JE vectors throughout the night on two bait types was also studied using three point moving averages. Hierarchical agglomerative cluster analysis was used to compare and classify mosquitoes on the basis of their similarity in biting rhythms.     

Nanoliter liquid metering in microchannels using hydrophobic patterns

Nanoliter-sized liquid drops can be accurately metered inside hydrophilic microchannels using a combination of hydrophobic surface treatment and air pressure. The technique involves spontaneously filling the microchannels up to a hydrophobic region and splitting a liquid drop by injecting air through a hydrophobic side channel. The hydrophobic regions are fabricated by using a patterned metal mask on a substrate. The patterned substrate is immersed in an isooctane solution containing 1H,1H,2H,2H-per-fluorodecyltrichlorosilane to form hydrophobic patches on the exposed surface. Stripping the metal mask leaves the hydrophobic patches and restores the hydrophilic substrate surface. Precise and accurate liquid volumes, ranging from 0.5 to 125 nanoliters, have been metered using this technique. Theoretical predictions of the pressure needed to meter drops compare well with the experimental values.     

Numerical study of mist film cooling on a flat plate with various numbers of deposition

Journal of Mechanical Science and Technology - An Eulerian-Eulerian multiphase solver of the open-source CFD software Open-Foam was used to numerically compute the film cooling investigation on a...