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Mountain ridges are valued by the Korean people as major and critical sources of natural resources and environment. Despite their recognised values, continuous exploitation and infrastructure development in forestlands have been causing large-scale degradation in mountains throughout the country. In response to this problem, our study supports recent efforts by the government to designate protection areas across the country. We build on the traditional classification of mountain ridges and apply a terrain-based spatial model to derive mountain ridge area boundaries. Based on the well-known mountain ridge system of the Korean peninsula, established in 1769, our approach was to select mountain ridgelines and boundaries using a terrain-based spatial model. The selected areas are generally located at high elevations with undulating terrain. They include a relatively large portion of ecologically important areas. A large portion of non-nationally owned forest is also found in the selected areas. Ecological importance and property rights would likely cause significant debate and conflicts among different social groups regarding designation of legally binding protection areas. Our model provides an explicit, scientific basis for the rigorous evaluation and area prioritisation as part of the protection area designation process. Application of our model can facilitate conversation on the country’s mountain ridge asset and public participation in the decision-making process.  相似文献   
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Journal of Mechanical Science and Technology - Recently, many researchers have studied to overcome some disadvantages of conventional sensing mechanisms. And the flexoelectric effect draw great...  相似文献   
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Sialidosis, caused by a genetic deficiency of the lysosomal sialidase gene (NEU1), is a systemic disease involving various tissues and organs, including the nervous system. Understanding the neurological dysfunction and pathology associated with sialidosis remains a challenge, partially due to the lack of a human model system. In this study, we have generated two types of induced pluripotent stem cells (iPSCs) with sialidosis-specific NEU1G227R and NEU1V275A/R347Q mutations (sialidosis-iPSCs), and further differentiated them into neural precursor cells (iNPCs). Characterization of NEU1G227R- and NEU1V275A/R347Q- mutated iNPCs derived from sialidosis-iPSCs (sialidosis-iNPCs) validated that sialidosis-iNPCs faithfully recapitulate key disease-specific phenotypes, including reduced NEU1 activity and impaired lysosomal and autophagic function. In particular, these cells showed defective differentiation into oligodendrocytes and astrocytes, while their neuronal differentiation was not notably affected. Importantly, we found that the phenotypic defects of sialidosis-iNPCs, such as impaired differentiation capacity, could be effectively rescued by the induction of autophagy with rapamycin. Our results demonstrate the first use of a sialidosis-iNPC model with NEU1G227R- and NEU1V275A/R347Q- mutation(s) to study the neurological defects of sialidosis, particularly those related to a defective autophagy–lysosome pathway, and may help accelerate the development of new drugs and therapeutics to combat sialidosis and other LSDs.  相似文献   
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We present recent developments in the field of austenitic steels with up to 18% reduced mass density. The alloys are based on the Fe-Mn-Al-C system. Here, two steel types are addressed. The first one is a class of low-density twinning-induced plasticity or single phase austenitic TWIP (SIMPLEX) steels with 25–30 wt.% Mn and <4–5 wt.% Al or even <8 wt.% Al when naturally aged. The second one is a class of κ-carbide strengthened austenitic steels with even higher Al content. Here, κ-carbides form either at 500–600°C or even during quenching for >10 wt.% Al. Three topics are addressed in more detail, namely, the combinatorial bulk high-throughput design of a wide range of corresponding alloy variants, the development of microstructure–property relations for such steels, and their susceptibility to hydrogen embrittlement.  相似文献   
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In this study, organic field-effect transistors (OFETs) with extended gate structure were fabricated for selective pH sensing applications. Indium tin oxide (ITO) was used as extended gate electrode as well as an active layer for H+ sensing. The threshold voltage of the fabricated ion-selective OFET was varied by the changes in the electrochemical potential at the ITO electrode surface upon its exposure to buffer solutions with variable pH values. The sensor showed excellent linearity and a high sensitivity of 57–59 mV/pH in the pH range of 2–12. The selectivity of the ITO sensing layer to H+ ions was also investigated by measuring the interfering effect of Ca2+ and K+ ions in the buffer pH solutions. The results showed that the Ca2+ and K+ ions weakly interfere with the selective pH sensing of the ITO-extended gate OFET sensor device.  相似文献   
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We study the structure and chemical composition of the κ-carbide formed as a result of isothermal transformation in an Fe–3.0Mn–5.5Al–0.3C alloy using transmission electron microscopy and atom probe tomography. Both methods reveal the evolution of κ-particle morphology as well as the partitioning of solutes. We propose that the κ-phase is formed by a eutectoid reaction associated with nucleation growth. The nucleation of κ-carbide is controlled by both the ordering of Al partitioned to austenite and the carbon diffusion at elevated temperatures.  相似文献   
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In this study, the authors compared the behavioral development of 4- to 8-year-old South Korean children placed in institutional care (n = 230) or adopted internationally (n = 382), with age of entry, parental status, reason for institutionalization, and postinstitutionalization parental contact as risk factors for institutionalized children. There was a placement effect of adoption and support for age of entry and parental status as risk factors. Relinquished children institutionalized before age 2 fared the poorest across groups. Children institutionalized after age 2 with deceased/unknown parents fared best among institutionalized children. Institutionalization due to family disruption was a risk for relinquished children only, whereas parental contact did not increase the risk for behavioral problems. The unique sample population and other limitations are discussed. (PsycINFO Database Record (c) 2010 APA, all rights reserved)  相似文献   
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An accelerated testing method for barium titanate (BaTiO3) dielectrics was proposed to elucidate deterioration behavior of dielectric constant based on the life-temperature relation. The accelerated degradation test (ADT) which was designed using various temperature ranges below and above Curie temperature (Tc) was focused on the optimized composition of dysprosium (Dy) and thulium (Tm) co-doped BaTiO3. The statistical analysis of the failure time data was performed to determine the optimum distribution as a goodness-of-fitness test. A scale parameter (η) and activation energy (Eα) were calculated in order to predict the life time of the co-doped BaTiO3, and there was difference between the expected life times according to the acceleration temperature rating of the ADT. The difference of deterioration mechanism around Tc could be deduced from the change of lattice parameter and polarization behavior. The drastic decrease of tetragonality and ferroelectric property caused by the phase transition of the co-doped BaTiO3 was verified in the temperature above Tc. Accordingly, the acceleration factor over Tc should be considered as reliability study of the BaTiO3 dielectrics for multilayer ceramic capacitors (MLCCs).  相似文献   
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