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ABSTRACTIn the last decade Australian academic libraries have increasingly aligned their research support services with assessment criteria used in the national research evaluation exercise (Excellence for Research in Australia). The same period has seen growing interest in research impact outside of traditional measures, such as bibliometrics. Social media has provided opportunities for research dissemination and new tools, altmetrics, to measure these activities have emerged. This article reports on research into the extent and nature of research support services at Australian academic libraries, how the services are managed, and the factors that influence their development and delivery. Quantitative and qualitative research methods were used to compare the findings with an earlier study and to provide a deeper understanding of research support in Australia. Three key themes, services, staff and resourcing, and relationships, are discussed in relation to the management and challenges faced in providing research support. 相似文献
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Osteoporosis becomes a serious health threat for older postmenopausal women by predisposing them to an increased risk of fracture.
Osteoporosis and associated fractures are an important cause of morbidity and mortality. Special attention is being paid to
early detection, management, and treatment of postmenopausal osteoporosis in women. Biochemical markers can enable dynamic
and rapid measurement of total body skeletal metabolism and will be clinically useful in the management of postmenopausal
osteoporosis women (PMO) and also for assessing the effects of antiresorptive therapy. With this view, we planned to assess
osteoclastic activity by determining urinary hydroxyproline in osteoporotic women. The aim of this study is to measure urinary
hydroxyproline (expressed as mg of hydroxyproline/g of creatinine) and serum ascorbic acid in postmenopausal women with osteoporosis
and without osteoporosis. These biochemical parameters were determined 3 months post antiresorptive therapy (alendronate + calcium + vitamin
D) in postmenopausal osteoporosis patients. 60 postmenopausal women with osteoporosis in the age group 45–60 years and 60
healthy postmenopausal women (normal bone mineral density) in the same age group were included in the study. Urinary hydroxyproline
levels were significantly increased (P < 0.001) in PMO at baseline level as compared to control group. These levels were decreased significantly (P < 0.001) post therapy in PMO patients. Serum vitamin C levels were significantly decreased (P < 0.001) in PMO patients at baseline level as compared to controls. No significant change occurred of serum vitamin C level
post therapy. Raised excretion of hydroxyproline at the baseline level might be due to increased degradation of collagen type
I from the bone matrix in osteoporosis. Breakdown of collagen seems to be lowered as reflected by lowering of hydroxyproline
excretion post antiresorptive therapy. Alteration in the concentration of this marker can be very well utilized to monitor
the effectiveness of therapy. Thus simple, direct urinary assay to measure bone resorption is very useful in monitoring the
therapy in PMO and may become an integral part of the management of osteoporosis. 相似文献
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