Writer identification approach based on bag of words with OBI features

Handwriter identification aims to simplify the task of forensic experts by providing them with semi-automated tools in order to enable them to narrow down the search to determine the final identification of an unknown handwritten sample. An identification algorithm aims to produce a list of predicted writers of the unknown handwritten sample ranked in terms of confidence measure metrics for use by the forensic expert will make the final decision.Most existing handwriter identification systems use either statistical or model-based approaches. To further improve the performances this paper proposes to deploy a combination of both approaches using Oriented Basic Image features and the concept of graphemes codebook. To reduce the resulting high dimensionality of the feature vector a Kernel Principal Component Analysis has been used. To gauge the effectiveness of the proposed method a performance analysis, using IAM dataset for English handwriting and ICFHR 2012 dataset for Arabic handwriting, has been carried out. The results obtained achieved an accuracy of 96% thus demonstrating its superiority when compared against similar techniques.     

Overexpression of Aldose Reductase Render Mouse Hepatocytes More Sensitive to Acetaminophen Induced Oxidative Stress and Cell Death

Acetaminophen (APAP) a commonly used drug for decrease the fever and pain but is capable to induced hepatotoxicity at over dose. This study was carried out to investigate the effect of APAP on the expression of anti-apoptotic and antioxidative defense genes, and whether aldose reductase over-expressing plasmid capable to protect against APAP-induced oxidative stress and cell death. APAP treatment induced oxidative stress and hepatotoxicity, and significantly increased aldose reductase mRNA and protein expression in mouse hepatocyte (AML-12). Unexpectedly, AML-12 cells over-expressing aldose reductase augmented APAP-induced reduction in cell viability, reactive oxygen species (ROS) production, glutathione (GSH) depletion and glutathione S-transferase A2 expression. Moreover, over-expression of aldose reductase potentiated APAP induced reduction on proliferating cell nuclear antigen, B cell lymphoma-extra large (bcl-x_L), catalase, glutathione peroxidase-1 (GPx-1) and abolished APAP-induced B-cell lymphoma 2 (bcl-2) inductions. Further, over-expression of aldose reductase significantly abolished AMP activated protein kinase (AMPK) activity in APAP-treated cells and induced p53 expression. This results demonstrate that APAP induced toxicity in AML-12, increased aldose reductase expression, and over-expression of aldose reductase render this cell more susceptible to APAP induced oxidative stress and cell death, this probably due to inhibition AMPK or bcl-2 activity, or may due to competition between aldose reductase and glutathione reductase for NADPH.     

Integrating design science research and design based research frameworks for developing education support systems

Education and Information Technologies - This paper proposes an integrated research framework that takes advantage of the similarities of design science research (DSR) and Design-based research...     

Family contexts of television

Educational technology research and development -     

Bioconversion of low quality lignocellulosic agricultural waste into edible protein by <Emphasis Type="Italic">Pleurotus sajor-caju</Emphasis> (Fr.) singer

Pleurotus sajor-caju (Fr.) Singer was cultivated on selected agro wastes viz. cotton stalks, groundnut haulms, soybean straw, pigeon pea stalks and leaves and wheat straw, alone or in combinations. Cotton stalks, pigeon pea stalks and wheat straw alone or in combination were found to be more suitable than groundnut haulms and soybean straw for the cultivation. Organic supplements such as groundnut oilseed cake, gram powder and rice bran not only affected growth parameters but also increased yields. Thus bioconversion of lignocellulosic biomass by P. sajor-caju offers a promising way to convert low quality biomass into an improved human food.     

Enterprise Systems: Curriculum design and assessment

We present a curriculum that prepares students for supporting large Enterprise Information Systems (EIS). EIS is best explained through the evolution of Enterprise Resource Planning (ERP). These systems evolved over the last years driven by (1) changing business requirements and (2) new development capabilities provided by technologies evolution and software vendors’ innovation. These developments led to a new discipline—Enterprise Information Systems, which deals with issues whose focus is on creating and sustaining business benefits through the utilization of corporate IT infrastructure assets. Currently, EIS knowledge is essentially acquired on the job after substantial time of experience building and longer career ladder scale. This paper presents an experience of a curriculum implementation that prepares students for the pervasive EIS landscape in meeting today’s corporate needs. Our IT-based educational approach is evaluated as an alternative to prevailing Business-based approaches to EIS instruction. In this IT-rooted approach, the curriculum is divided into four sections: a Core IT block of courses followed by two progressive-levels of advanced EIS-related specialized subjects, and an industry-oriented field-training experience. Initially, a Core IT background provides a foundation for IT innovation in developing EIS components at sophomore-level. A junior-level of specialized instruction introduces integrated modules which form EIS platforms. Finally, supporting technologies of EIS-related processes and workflows are presented at senior-level of specialized EIS instruction. An assessment case study of the proposed Enterprise System programs is carried out through which we discuss the results of the curriculum performance.